A5103088000- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Immune cells in cancer
- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Chemokine receptors and signaling
- Cancer, Hypoxia, and Metabolism
- Osteoarthritis Treatment and Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Inflammatory mediators and NSAID effects
- Diagnosis and treatment of tuberculosis
- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
Third Hospital of Hebei Medical University
2024
Union Hospital
2024
Hebei Medical University
2024
Huazhong University of Science and Technology
2024
Affiliated Hospital of Nantong University
2020-2023
Nantong University
2020-2023
Second Hospital of Yichang
2023
China Three Gorges University
2023
Harbin Medical University
2022
Wuhan University
2021
The balance between antioxidants and reactive oxygen species (ROS) critically regulates tumor initiation progression. However, whether how the tumor-favoring redox status is controlled by cytokine networks remain poorly defined. Here, it shown that IL-36γ IL-36Ra reciprocally regulate progression of non-small cell lung cancer (NSCLC) modulating glutathione metabolism ROS resolution. Knockout, inhibition, or neutralization significantly inhibits NSCLC prolongs survival Kras
Stratification of tumors is necessary to achieve better clinical outcomes. Hepatocellular carcinoma (HCC) commonly associated with mutation the TP53 gene and heterogeneity in immune cell content. However, mutation-associated immunotype HCC has not been reported yet. This study aimed identify HCC.The annotation format (MAF) document, mRNA expression data, data patients were downloaded from publicly available The Cancer Genome Atlas (TCGA) portal. Data 332 analyzed this study. Infiltrating...
Immune dysfunction and pro-oncogenic inflammation play critical roles in malignant progression non-response to immunotherapy for hepatocellular carcinoma (HCC). In particular, PD-1/PD-L1 blockade therapy could induce durable tumor remissions improve the prognosis of patients a certain extent. However, PD-L1, as promising biomarker, has limited knowledge about its relevance microenvironment (TME) characterization endogenous inflammatory immune responses. this study, we systematically...
Abstract Background. Coronin 2A (CORO2A) is a member of the coronin family and reportedly functions as an oncogene in certain malignancies, although its correlation with prognosis immune infiltration different cancers remains unclear. Methods. Data were collected from University California Santa Cruz (UCSC), Human Protein Atlas (HPA), Tumor Immune Estimation Resource (TIMER), Tumor-Immune System Interactions (TISIDB) Gene Set Enrichment Analysis (GSEA) databases. The differential expression...