A5103250915- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Hip disorders and treatments
- Cellular and Composite Structures
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular and Diving-Related Complications
- Titanium Alloys Microstructure and Properties
- Dental Implant Techniques and Outcomes
- Genetic Syndromes and Imprinting
- Esophageal and GI Pathology
- Nanoplatforms for cancer theranostics
- Collagen: Extraction and Characterization
- biodegradable polymer synthesis and properties
- 3D Printing in Biomedical Research
- Bone Metabolism and Diseases
- Osteoarthritis Treatment and Mechanisms
- Magnesium Alloys: Properties and Applications
- Pericarditis and Cardiac Tamponade
- Cardiovascular Syncope and Autonomic Disorders
- Lung Cancer Diagnosis and Treatment
- Elasticity and Material Modeling
- Cardiovascular Health and Disease Prevention
Second Affiliated Hospital of Jilin University
2015-2025
George Washington University
2023
Capital Medical University
2009
In orthopedic implant development, incorporating a porous structure into implants can reduce the elastic modulus to prevent stress shielding but may compromise yield strength, risking prosthesis fracture. Bamboo's natural structure, with its exceptional strength-to-weight ratio, serves as inspiration. This study explores biomimicry using bamboo-inspired scaffolds (BISs) resembling cortical bone, assessing their mechanical properties and fluid characteristics. The BIS consists of two 2D units...
Abstract Background Changes in vascular function are closely associated with the development of cardiovascular disease (CVD). Pulse wave velocity (PWV) is a potential indicator dysfunction; it allows noninvasive assessment arterial stiffness. Currently, evidence for effects different classes antidiabetic drugs on stiffness remains limited. In this study, network meta‐analysis (NMA) was performed to explore associations between changes and first‐line by evaluating PWV patients metabolic...
Mineralized collagen (MC) is the fundamental unit of natural bone tissue and can induce regeneration. Unmodified MC has poor mechanical properties a single component, making it unable to cope with complex physiological environment. In this study, we introduced sodium alginate (SA) vascular endothelial growth factor (VEGF) into material construct functionalized mineralized (FMC) good strength ability continuously release factors. The FMC filled pores 3D printed titanium alloy scaffold form...
Background and objectiveObesity is one of the risk factors for osteoarthritis. The end-stage treatment osteoarthritis total knee arthroplasty (TKA). However, it remains controversial whether a high body mass index (BMI) affects initial stability femoral prosthesis after TKA. Finite element analysis (FEA) was used to investigate this question in study.MethodsFour femur models that assembled with TKA components were reconstructed divided into BMI group normal group. three-dimensional femurs...
The femoral anterior bow is an important factor in matching a implant to femur. However, its morphology the Chinese population has rarely been reported. In this study, three-dimensional measurement approach was adopted provide accurate data. aim supply reference for designing long-stemmed prosthesis that more suitable people.Computed tomography data were collected from both lower limbs of 96 normal volunteers and reconstructed into model using Mimics software. parameters measured medical...
Abstract Improper osteotomy during total knee arthroplasty (TKA) can lead to anterior femoral notching, which increases the risk of periprosthetic fractures due stress concentration. One potential solution is addition an intramedullary stem component. However, optimal length remains unclear. In this study, we aimed determine using finite element models. Finite models femurs were developed with unstemmed prostheses and lengths 50, 75, 100 mm. Under squat loading conditions, von Mises at notch...
This study aimed to investigate the optimal sagittal positioning of uncemented femoral component in total knee arthroplasty minimize risk aseptic loosening and periprosthetic fracture.
Bilateral VCA of 50 DDH patients and 56 normal volunteers were measured by Mimics software in the 3D method X-ray 2D. Two (the upper lower VCA) both two methods. Every was observer A B for twice separately. The statistical analyses differences calculated among measurements VCA.The mean value 4.95° ± 0.76° group 5.56° 0.62° with significant difference (t = -6.457, p < 0.01). larger than 2D, VCA. indicated statistically significant. 0.60° smaller volunteers. 0.58° patients.Compared to X-ray,...
Objective EndotheUn levels in the plasma were shown to increase as cardiac function became deteriorated.We investigate association of endothelin pericardial fluid with patients rheumatic heart disease (RHD).Methods The study involved 51 patients,24 male and 27 female,who underwent elective valvuloplasty or valve replacement for diseases.Doppler echocardiography was performed within 24 hours after admission all by 2 experienced attending doctors.Endothelin concentrations measured...