A5008877702- Microbial Fuel Cells and Bioremediation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer-related molecular mechanisms research
- Thyroid Cancer Diagnosis and Treatment
- Circular RNAs in diseases
- VLSI and Analog Circuit Testing
- Glutathione Transferases and Polymorphisms
- Anaerobic Digestion and Biogas Production
- Genomics, phytochemicals, and oxidative stress
- Liver Disease Diagnosis and Treatment
- MicroRNA in disease regulation
- Cardiovascular Health and Disease Prevention
- Diabetes Treatment and Management
- Low-power high-performance VLSI design
- Folate and B Vitamins Research
- Blood Pressure and Hypertension Studies
- VLSI and FPGA Design Techniques
- Gout, Hyperuricemia, Uric Acid
- Membrane-based Ion Separation Techniques
- Supercapacitor Materials and Fabrication
- RNA modifications and cancer
- Integrated Circuits and Semiconductor Failure Analysis
- Electrochemical sensors and biosensors
- Peer-to-Peer Network Technologies
- Mitochondrial Function and Pathology
Ningbo First Hospital
2022-2025
Changzhi Medical College
2020-2025
Yunnan Normal University
2021-2024
Aerospace Center Hospital
2023-2024
Wuhan University
2013-2024
Zhongnan Hospital of Wuhan University
2013-2024
First Affiliated Hospital of Chengdu Medical College
2022-2024
Chinese PLA General Hospital
2018-2023
Shanghai Jiao Tong University
2022
ShanghaiTech University
2021-2022
Breast cancer is the most common type in female. As microRNAs play vital role breast cancer, this study aimed to explore molecular mechanism and clinical value of miR-21 cancer. qRT-PCR was performed detect levels plasma 127 healthy controls, 82 benign tumor, 252 patients, as well cell lines. Transwell wound healing assay were used analyze metastasis response inhibitor. Colony formation eFluor™ 670 based flow cytometric analysis test proliferation following inhibitor treatment. Leucine...
A simple and readily available biomarker can provide an effective approach for the surveillance of type 2 diabetes mellitus (T2DM) in elderly. In this research, we aim to evaluate role triglyceride high-density lipoprotein cholesterol (TG/HDL-C) ratio as indicator new-onset T2DM elderly Chinese population aged over 75 years.This longitudinal retrospective cohort study was conducted using a free database from health check screening project China. Participants with baseline TG HDL measurements...
While publish-subscribe systems have attracted much research interest since the last decade, few established benchmarks emerged, and there has been little characterization of how are used in practice. This paper examines RSS, a newly emerging, widely system for Web micronews. Based on trace study spanning 45 days at medium-size academic department periodic polling approximately 100,000 RSS feeds, we extract characteristics content usage. We find that workload resembles size popularity; feeds...
To investigate the relationship among 18 heavy metals, microsatellite instability (MSI) status, ERCC1, XRCC1 (rs25487), BRAF V600E and 5 tumor markers their role in development of colorectal cancer (CRC).A total 101 CRC patients 60 healthy controls were recruited present study. The levels metals measured by ICP-MS. MSI status genetic polymorphism determined PCR (FP205-02, Tiangen Biochemical Technology Co., Ltd., Beijing, China) Sanger sequencing. Spearman's rank correlation was used to...
The introduction of simulation-based analog synthesis tools creates a new challenge for modeling. These routinely visit 103 to 105 fully simulated circuit solution candidates. What might we do with all this data? We show how adapt recent ideas from large-scale data mining build models that capture significant regions visited performance space, parameterized by variables manipulated synthesis, trained the points during synthesis. Experimental results can automatically useful nonlinear...
In this paper, we describe the design and implementation of a distributed operating system for ad hoc networks. Our simplifies programming networks extends total lifetime by making entire network appear as single virtual machine. It automatically transparently partitions applications into components dynamically finds them placement on nodes within to reduce energy consumption increase longevity. This paper describes our model, outlines examines efficiency approach through extensive...
Long intergenic non-coding RNA 00152 (LINC00152) is aberrantly expressed in various human malignancies and plays an important role the pathogenesis. Here, we found that LINC00152 upregulated hepatocellular carcinoma (HCC) tissues as compared to adjacent non-neoplastic tissues; gain-and-loss-of-function analyses vitro showed facilitates HCC cell cycle progression through regulating expression of CCND1. knockdown inhibits tumorigenesis vivo. MS2-RIP analysis indicated binds directly...
The hemoglobin glycation index (HGI) was developed to quantify glucose metabolism and individual differences proved be a robust measure of glycosylated (HbA1c) bias. Here, we aimed explore the relationship between different HGIs risk 5-year major adverse cardiovascular events (MACEs) by performing large multicenter cohort study in China.A total 9791 subjects from Risk Evaluation Cancers Chinese Diabetic Individuals: Longitudinal Study (the REACTION study) were divided into five subgroups...
While publish-subscribe systems have attracted much research interest since the last decade, few established benchmarks emerged, and there has been little characterization of how are used in practice.This paper examines RSS, a newly emerging, widely system for Web micronews.Based on trace study spanning 45 days at medium-size academic department periodic polling approximately 100,000 RSS feeds, we extract characteristics content usage.We find that workload resembles size popularity; feeds...
Accurately estimating the rare failure rates for nanoscale circuit blocks (e.g., static random-access memory, D flip-flop, etc.) is a challenging task, especially when variation space high-dimensional. In this paper, we propose novel scaled-sigma sampling (SSS) method to address technical challenge. The key idea of SSS generate random samples from distorted distribution which standard deviation (i.e., sigma) scaled up. Next, rate accurately estimated these by using an analytical model...
Abstract Background Changes in vascular function are closely associated with the development of cardiovascular disease (CVD). Pulse wave velocity (PWV) is a potential indicator dysfunction; it allows noninvasive assessment arterial stiffness. Currently, evidence for effects different classes antidiabetic drugs on stiffness remains limited. In this study, network meta‐analysis (NMA) was performed to explore associations between changes and first‐line by evaluating PWV patients metabolic...
Inadequate sleep duration is associated with a higher risk of type 2 diabetes and the relationship nonlinear. We aim to assess curve between night incidence in China.A cohort 11,539 participants from REACTION study without at baseline (2011) were followed until 2014 for development diabetes. The average number hours per was grouped. Incidence rates odds ratios (ORs) calculated each category.Compared people who 7 8 h/night, longer (≥9 h/night) had greater (OR: 1.27; 95% CI: 1.01-1.61), while...
Background The association between the triglyceride–glucose (TyG) index and type 2 diabetes mellitus (T2DM) in older adults has not been fully understood. This research aims to explore TyG incidence of T2DM an Chinese population aged over 75 years. Methods longitudinal analysis study was performed based on a database from health check screening program China. participants were stratified quintile ranges (Q1 Q5 groups). defined as fasting plasma glucose (FPG) ≥ 7.00 mmol/L and/or...
Background Serum lipids were found to be correlated with chronic kidney disease and cardiovascular disease. Here, we aimed research the potential causal associations between five serum lipid parameters risk of diabetic nephropathy using several Mendelian Randomization methods. Methods Genetic data was obtained from UK Biobank datasets. Causal effects estimated multiple MR Heterogeneity pleiotropy tests performed. Results analysis revealed that HDL-C TG exhibited ( P <0.05). Similar...
For the patients who are suffering from type 2 diabetes, blood glucose level could be affected by multiple factors. An accurate estimation of trajectory is crucial in clinical decision making. Frequent measurement serves as a good source data to train machine learning models for prediction purposes. This study aimed at using methods predict diabetic patients. We investigated various parameters influencing glucose, well determined most effective algorithm predicting glucose.273 were recruited...
The continuous technology scaling brings about high-dimensional performance variations that cannot be easily captured by the traditional response surface modeling. In this paper we propose a new statistical regression (STAR) technique applies novel strategy to address high dimensionality issue. Unlike most modeling techniques solve model coefficients from over-determined linear equations, STAR determines all unknown moment matching. As such, large number of (e.g., 103~105) can extracted...
Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed investigate effects and mechanisms of supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model provide experimental evidence for resistance improvement by supplementation.Rat was developed high-fat diet along low dose streptozotocin (STZ) treatment. Magnesium supplement given orally mixing diet. Serum level, sensitivity,...