A5088253968- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Cellular and Composite Structures
- Spinal Fractures and Fixation Techniques
- Shoulder Injury and Treatment
- Titanium Alloys Microstructure and Properties
- Anatomy and Medical Technology
- Orthopedic Surgery and Rehabilitation
- Sarcoma Diagnosis and Treatment
- Spaceflight effects on biology
- Advanced X-ray and CT Imaging
- Additive Manufacturing and 3D Printing Technologies
- Electrospun Nanofibers in Biomedical Applications
- Tendon Structure and Treatment
- 3D Printing in Biomedical Research
- Lower Extremity Biomechanics and Pathologies
- Reconstructive Surgery and Microvascular Techniques
- Medical Imaging Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
Northeastern University
2025
Second Affiliated Hospital of Jilin University
2015-2024
Universidad del Noreste
2023
Jilin University
2015-2021
Henan Institute of Science and Technology
2016
Chinese Academy of Sciences
1998-2015
Changchun Institute of Applied Chemistry
2015
Dana (United States)
2000
Institute of Biophysics
1998
Titanium alloy prostheses have been widely used for the treatment of orthopedic diseases, in which interconnected porosity and appropriate pore size are crucial osseointegration capacity. Three-dimensional (3D) printing technology provides an efficient method to construct prosthesis scaffolds with controllable internal surface structure, but high-porosity (>60%) diameters below 300 μm as implants structures has not yet studied. In this work, four types titanium more than 70% were...
Solid titanium alloys are extensively employed in orthopedic applications due to their reliable mechanical strength, but the stress shielding phenomenon caused by its high elastic modulus and disadvantage of lack bone integration may lead clinical complications. The design porous structure is a feasible approach reduce promote vascular ingrowth. This paper reviewed application current challenges solid implants orthopedics. To address drawbacks explore that can effectively integrate with...
In orthopedic implant development, incorporating a porous structure into implants can reduce the elastic modulus to prevent stress shielding but may compromise yield strength, risking prosthesis fracture. Bamboo's natural structure, with its exceptional strength-to-weight ratio, serves as inspiration. This study explores biomimicry using bamboo-inspired scaffolds (BISs) resembling cortical bone, assessing their mechanical properties and fluid characteristics. The BIS consists of two 2D units...
Abstract The development of cellular materials with adjustable mechanical properties, total porosity (Tp), and elastic modulus (E) similar to those natural bone are eternal pursuits in the field implants. Designing manufacturing an implant that fulfills all these requirements is a challenging task. In this study, inspired by trabecular structure developed biomimetic structural material. Laser powder bed fusion (L‐PBF) utilized create Comprehensive valuations both material conducted using...
Clear cell renal carcinoma (ccRCC) is the predominant human cancer with surging incidence and fatality lately. Hyperactivation of hypoxia-inducible factor (HIF) mammalian target rapamycin (mTOR) signaling are common signatures in ccRCC. Herein, we employed spontaneous ccRCC model to demonstrate indispensability an underappreciated Ser/Thr kinase, CDKL3, initiation progression Ablation CDKL3 does not affect normal kidney, but abrogates Akt-mTOR hyperactivity thoroughly prevents formation...
BACKGROUND:We explored the application of 3-dimensional (3D) printing technology in treating giant cell tumors (GCT) proximal tibia. A tibia block was designed and produced through 3D technology. We expected that this 3D-printed would fill bone defect after en-bloc resection. Importantly, block, combined with a standard knee joint prosthesis, provided attachments for collateral ligaments knee, which can maintain stability. MATERIAL AND METHODS:A computed tomography (CT) scan taken both...
Background and objective: The osteoporotic vertebral compression fracture (OVCF) has an incidence of 7.8/1000 person-years at 55-65 years. At 75 years or older, the increases to 19.6/1000 in females 5.2-9.3/1000 males. To solve this problem, percutaneous vertebroplasty (PVP) was developed recent been widely used clinical practice treat OVCF. Are effects unilateral (UPVP) bilateral (BPVP) same? purpose study compare biomechanical differences between UPVP BPVP using finite element analysis....
In anterior cervical discectomy and fusion (ACDF), an interbody device is essential implant. An unsuitable can cause postoperative complications, including subsidence nonunion. We designed a customized intervertebral to reduce complications validated it by finite element analysis. Herein, we built non-homogeneous model of the C3-7 spine. Three implant models (customized cage, commercial bone graft cage) were constructed placed in C45 segment after ACDF surgery. The simulated range motion...
Abstract Rationale: This paper describes the application of individual customized 3-dimensional (3D) printed macro-porous Ti6Al4 V shoulder prosthesis in revision total arthroplasty (TSA) for patient with severe bone defects. Patient concerns: A 47-year-old male had been under proximal humeral resection and TSA due to chondrosarcoma 6 years ago, but a second surgery insert new was then performed because became loose 2 months ago leaving defects which conventional not suitable TSA. American...
Recently, clinical application of 3D printed model was increasing. However, there no systemic study for confirming the precision and reliability model. Some senior doctors mistrusted its in application. The purpose this to evaluate stereolithography appearance (SLA) related parameters were selected research SLA computed tomography (CT) data bone/prosthesis collected reconstructed. anatomical measured statistical analysis performed; intraclass correlation coefficient (ICC) used similarity...
Abstract The purpose of this study was to investigate metal artifact reduction effect orthopedics (O-Mar) algorithm in computer tomography (CT) image patients who have undergone total hip arthroplasty (THA) or knee (TKA). 35 cases underwent TKA THA been recruited study. CT joint obtained with Philips 256-row scanner. Tube voltages 120 and 140 kilovolt peak (KVP) were set. Afterwards, reconstructed by O-Mar reduce artifact. Grade quality severity would be taken into qualitative evaluation....
Background and objectiveObesity is one of the risk factors for osteoarthritis. The end-stage treatment osteoarthritis total knee arthroplasty (TKA). However, it remains controversial whether a high body mass index (BMI) affects initial stability femoral prosthesis after TKA. Finite element analysis (FEA) was used to investigate this question in study.MethodsFour femur models that assembled with TKA components were reconstructed divided into BMI group normal group. three-dimensional femurs...
Introduction: Anterior cervical discectomy and fusion (ACDF) is a standard procedure for treating symptomatic degenerative disease. The cage plate constructs (CPCs) are widely employed in ACDF to maintain spinal stability provide immediate support. However, several instrument-related complications such as dysphagia, subsidence, adjacent segment degeneration have been reported the previous literature. This study aimed design novel individualized zero-profile (NIZP) evaluate its potential...