A5100385873- Osteoarthritis Treatment and Mechanisms
- Periodontal Regeneration and Treatments
- Colorectal Cancer Surgical Treatments
- Mesenchymal stem cell research
- Maternal and fetal healthcare
- Prenatal Screening and Diagnostics
- Heterotopic Ossification and Related Conditions
- Ectopic Pregnancy Diagnosis and Management
- Bone fractures and treatments
- Bone Tumor Diagnosis and Treatments
- Long-Term Effects of COVID-19
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Appendicitis Diagnosis and Management
- Dermatological and Skeletal Disorders
- COVID-19 Clinical Research Studies
- Tendon Structure and Treatment
- Liver Disease Diagnosis and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Uterine Myomas and Treatments
- Colorectal and Anal Carcinomas
- Medical Imaging and Pathology Studies
- Sarcoma Diagnosis and Treatment
- Innovations in Aquaponics and Hydroponics Systems
- Cardiovascular Issues in Pregnancy
National Defense Medical Center
2016-2025
Tri-Service General Hospital
2016-2025
Air Force Medical University
2021-2025
Fu Jen Catholic University
2025
Henan University of Science and Technology
2024
Gilead Sciences (United States)
2020-2024
Shandong First Medical University
2024
Shandong Provincial Hospital
2024
First Hospital of Jilin University
2021-2023
Jilin University
2021-2023
Abstract Ideal cartilage tissue engineering requires scaffolds featuring good biocompatibility, large pore structure, high mechanical strength, as well minimal invasion procedure. Although significant progress has been made in the development of polymer scaffolds, construction smart systems with all desired properties is still emerging a challenge. The thermogels stereocomplex 4‐arm poly(ethylene glycol)–polylactide (PEG–PLA) (scPLA gel ) and cholesterol‐modified PEG–PLA (scPLA–Chol from...
Abstract Brain-derived extracellular vesicles participate in interorgan communication after traumatic brain injury by transporting pathogens to initiate secondary injury. Inflammasome-related proteins encapsulated brain-derived can cross the blood‒brain barrier reach distal tissues. These inflammatory dysfunction, such as neurogenic heterotopic ossification. This recurrent condition is highly debilitating patients because of its relatively unknown pathogenesis and lack effective prophylactic...
Abstract Heterotopic ossification (HO) comprises the abnormal formation of ectopic bone in extraskeletal soft tissue. The factors that initiate HO remain elusive. Herein, we found calcified apoptotic vesicles (apoVs) led to increased calcification and stiffness tendon extracellular matrix (ECM), which initiated M2 macrophage polarization progression. Specifically, single‐cell transcriptome analyses different stages revealed apoVs were primarily secreted by a PROCR + fibroblast population. In...
Objective: To investigate the bone augmentation effects of domestic decellularized porcine small intestinal submucosa (PSIS) absorbable biomembrane and bovine pericardium tissue (BPT) in guided regeneration (GBR) for single-tooth implantation diabetic patients. Methods: A prospective case-control study was conducted with 48 patients who received implant restoration at Department Prosthodontics, School Stomatology. The Fourth Military Medical University, between January 2023 2024. Patients...
Insulin resistance (IR) is the core for type 2 diabetes and metabolic syndrome. The homeostasis assessment model a straightforward practical tool quantifying insulin (HOMA-IR). Multiple adaptive regression spline (MARS) machine learning method used in many research fields but has yet to be applied estimating HOMA-IR. This study uses MARS build an equation estimate HOMA-IR pre-menopausal Chinese women based on sample of 4,071 healthy aged 20-50 with no major diseases medication use blood...
BACKGROUND:We explored the application of 3-dimensional (3D) printing technology in treating giant cell tumors (GCT) proximal tibia. A tibia block was designed and produced through 3D technology. We expected that this 3D-printed would fill bone defect after en-bloc resection. Importantly, block, combined with a standard knee joint prosthesis, provided attachments for collateral ligaments knee, which can maintain stability. MATERIAL AND METHODS:A computed tomography (CT) scan taken both...
This study aimed to report our experience of emergent bilateral hypogastric (internal iliac) artery ligation (HAL) in the management intractable postpartum hemorrhage (PPH) a tertiary care center. Patients with severe that could not be controlled conservative were retrospectively reviewed from January 2013 December 2017. Data retrieved patients' hospital records. Two cases involving both transcatheter uterine embolization (TAE) and HAL excluded. A total 40 patients included analysis during...
The growth plate is a cartilaginous tissue with three distinct zones. Resident chondrocytes are highly organized in columnar structure, which critical for the longitudinal of immature long bones. Once injured, may potentially be replaced by bony bar formation and, consequently, cause limb abnormalities children. It well-known that essential step repair remolding structure chondrocytes. To achieve this, we prepared an anatomy-inspired bionic Poly(ε-caprolactone) (PCL) scaffold stratified...
Background Primary aldosteronism (PA) is associated with higher atrial fibrillation prevalence and other cardiovascular complications. However, the effect of target treatment to prevent new-onset (NOAF) remains unclear. This study investigated incidence NOAF under different strategies in patients PA. Methods Results We analyzed longitudinal data for PA without history from 1997 2009 within National Health Insurance Research Database Taiwan. Patients essential hypertension matched by...
Recently, therapy with bone marrow mesenchymal stem cells (BMMSCs) has been attempted to relieve rheumatoid arthritis (RA) and reconstruct cartilage injury. However, treatment unsuccessful in complete prevention of persistent destruction resulted inferior outcomes regeneration. Scaffolds are an important construct the field tissue engineering, but their role not yet fully examined. Here, we transplanted two types scaffold-assisted BMMSCs: fibrin gel-...
Incarcerated gravid uterus is a rare complication of pregnancy and can become critical condition during delivery. For extremely uncommon cases that persist to the third trimester, correct diagnosis before delivery appropriate management associated complications are important. This was first case full-term with incarcerated uterus, reported at medical center. The not diagnosed pregnancy, which led serious cesarean delivery; however, prognosis favorable because timely management. Based on...
This case-control study compared the short-term clinical efficacy of natural orifice specimen extraction surgery (NOSES) using a prolapsing technique and conventional laparoscopic-assisted approach for low rectal cancer.To further explore application value transanal placement anvil to evaluate NOSES resecting specimens cancer, as well provide theoretical basis its extensive application.From June 2015 2018, 108 consecutive cancer resections were performed at our center. Among them, 26...
Background: In women after menopause, the incidence of diabetes mellitus increases. Increased insulin resistance (IR), decreased glucose effectiveness (GE), and first second phases secretion (FPIS SPIS), are four most important factors that trigger intolerance (diabetogenic factor [DF]). cross-sectional study, we enrolled nondiabetic between ages 45 60 years to observe changes in DFs during perimenopausal period elucidate underlying mechanisms menopausal women. Methods: We randomly 4194 who...
Objective Congenital dislocation of the radial head (CRHD) is a rare condition, with bilateral anterior cases being even less common worldwide. Only few had residual pain after adulthood, when left untreated. Herein, we describe an adult case CRHD significant and snapping during motion. The aim this study was to report physical radiological findings, treatment methods, short-term outcomes our review in literature. Patient A 21-year-old male patient presented hospital chief complaints...
The purpose of this study was to evaluate the clinical results and safety arthroscopic microfracture with ankle suspended on a shoulder-holding traction frame for simultaneous anterior posterior arthroscopy in prone position.Between May 2010 January 2016, 31 patients osteochondral lesions talus (OLTs) were treated position patient prone. Ankle distraction achieved by suspending affected frame. 100 mm visual analog scale (VAS) Foot Function Index (FFI) checked preoperatively at final...
The discharge of water effluents from aquaculture systems pollutes the waters ambient environment and is a major concern in development sustainable aquaculture.In this study, we examined effects fish stocking density on quality biomass yields recirculating aquaponicmembrane filtration system used for co-culturing tilapia (Oreochromis niloticus) spinach (Ipomoea aquatica).The was composed tank, sludge tank with membrane, hydroponic tank.Tilapia (average initial weight, 1.8 g) at three...
The combination of ledipasvir and sofosbuvir (LDV/SOF) has been approved for the treatment various hepatitis C virus (HCV) genotypes across many countries. This article presents an integrated analysis three prospective phase II/III trials in Asia-Pacific region to evaluate efficacy safety 12 weeks LDV/SOF HCV genotype 2 patients without cirrhosis or with compensated cirrhosis.A total 200 were included analysis. primary end-point was rate sustained virologic response after end therapy...