A5018086416- Neuroendocrine Tumor Research Advances
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal disorders and treatments
- Eosinophilic Esophagitis
- Liver Diseases and Immunity
- Immunodeficiency and Autoimmune Disorders
- Ovarian cancer diagnosis and treatment
- Bone and Joint Diseases
- CAR-T cell therapy research
- Endoplasmic Reticulum Stress and Disease
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Spectroscopy Techniques in Biomedical and Chemical Research
- Gynecological conditions and treatments
- Cancer-related molecular mechanisms research
- Organ Transplantation Techniques and Outcomes
- IgG4-Related and Inflammatory Diseases
- Liver Disease Diagnosis and Treatment
- Transgenic Plants and Applications
- Tuberous Sclerosis Complex Research
- Genetic factors in colorectal cancer
- Chronic Myeloid Leukemia Treatments
- Uterine Myomas and Treatments
- Parasitic Infections and Diagnostics
- Syphilis Diagnosis and Treatment
University of Miami
2020-2025
Jackson Memorial Hospital
2020-2021
University of Louisville
2019-2021
University of California, San Diego
2020
University of Illinois Chicago
2014-2017
Rush University
2011
Rush University Medical Center
2011
Abstract Hepatic segmental atrophy is an underrecognized pseudotumor that can cause diagnostic challenges. These lesions be mass-forming and demonstrate a range of pathologic features lead to errors on both imaging studies, frozen section, in biopsy material. The aim this study was better understand the clinicopathologic condition as well its association with cardiovascular disease. A retrospective computerized search files two institutions conducted spanning 2012 2024. All surgical slides...
Cholera toxin B subunit (CTB) exhibits broad-spectrum biologic activity upon mucosal administration. Here, we found that a recombinant CTB containing an endoplasmic reticulum (ER) retention motif (CTB-KDEL) induces colon epithelial wound healing in colitis via the activation of unfolded protein response (UPR) cells. In Caco2 cell model, CTB-KDEL, but not or CTB-KDE, facilitated migration interaction with KDEL receptor, localization ER, UPR activation, and subsequent TGF-β signaling....
Although the oral anticoagulant warfarin has undoubtedly saved lives and reduced number of strokes in patients with atrial fibrillation, it is a cumbersome medication to manage take. Novel anticoagulants, such as dabigatran, offer therapeutic anticoagulation without requisite blood testing or dietary restrictions. We conducted survey attitudes enrolled clinic toward switching novel anticoagulant. From September December 2010, written was offered 180 Warfarin Clinic Rush University Medical...
BACKGROUND: Colon cancer survival is dependent on metastatic potential and treatment. Large RNA-sequencing data sets may assist in identifying colon cancer-specific biomarkers to improve patient outcomes. OBJECTIVE: This study aimed identify a highly specific biomarker for overall adenocarcinoma by using an set. DESIGN: Raw clinical patients with (n = 271) were downloaded from The Cancer Genome Atlas. A binomial regression model was used calculate differential RNA expression between paired...
EoE in children presents with four main symptoms. Most common symptoms exhibited by our clinic population are dysphagia (D) and abdominal pain (AP). Despite similar treatments, we found an earlier study that the outcomes between these two groups were different. Therefore, investigated if there exist any histological differences could further knowledge of EoE. Aim . To compare esophageal histology detail, apart from eosinophil count, EoE-D EoE-AP. Method Biopsies patients EoE-AP reevaluated...
Hepatocellular carcinoma (HCC) is the most common form of primary hepatic carcinoma. HCC ranks fourth prevalent malignant tumor and third leading cause cancer related death in world. develops context chronic liver disease its evolution characterized by progression through intermediate stages to advanced possibly even death. The sequence hepatocarcinogenesis includes development cirrhosis, followed dysplasia, hepatocellular carcinoma.1 We addressed utility Fourier Transform Infrared (FT-IR)...
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Ortiz Requena, Domenika MD; Poveda, Julio McDonald, Oliver G. MD, PhD; Ronquillo, Nemencio Garcia-Buitrago, Monica Montgomery, Elizabeth A. MD Author Information
Lymphangiomyomatosis is a member of the PEComa family, and usually involves pulmonary parenchyma middle-aged females. Infrequently, it may involve abdominal retroperitoneal lymph nodes, rarely has been described to be associated with fallopian tube-type ciliated epithelium co-existing in one neoplasm. To increase our understanding this unusual tumor, we describe morphology genetics case review literature. We present 50-year-old female found have 12.5 7.7 cm cystic masses, its unique...
Introduction: Immune-mediated hepatitis (IMH) is common and occurs in up to 16% of patients treated with checkpoint inhibitors (ICI). Early diagnosis intervention key prevent hepatic decompensation. Severity hepatotoxicity graded according Common Terminology Criteria for Adverse Events version 4.03 ranges from Grades 1-5. We present a case steroid-refractory Grade 4 IMH that required an additional immunomodulator resolution. Case Description/Methods: A 77-year-old woman ocular melanoma liver...
Introduction: Common Variable Immunodeficiency (CVID), a disorder which results in impaired differentiation of B cells and defective immunoglobulin production, most commonly presents with recurrent infections. Dysregulation the immune system leads to autoimmunity, inflammatory disorders, and/or malignant disease. The liver is less frequently involved CVID differential diagnosis broad patients who present elevated enzymes. We case severe transaminitis young patient longstanding CVID. Case...
Introduction: Syphilitic hepatitis (SH) is a rare manifestation of secondary syphilis presenting with cholestatic liver injury that can be confused other disease. We present case ocular and SH positive anti-mitochondrial antibody (AMA) anti-smooth muscle (ASMA) which proved to immunologic epiphenomena. Case Description/Methods: A 64-year-old male hypertension, chronic kidney disease Hepatitis C infection treated ledipasvir sofosbuvir in 2013 achieving SVR12 was admitted for orthostatic...