- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Diabetic Foot Ulcer Assessment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Central Venous Catheters and Hemodialysis
- Advanced MRI Techniques and Applications
- Infective Endocarditis Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Cardiovascular Health and Disease Prevention
- Orthopaedic implants and arthroplasty
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Vascular anomalies and interventions
- Cardiovascular Disease and Adiposity
- Pain Mechanisms and Treatments
- Abdominal vascular conditions and treatments
- Hemodynamic Monitoring and Therapy
- Cancer, Lipids, and Metabolism
Heinrich Heine University Düsseldorf
2015-2024
Düsseldorf University Hospital
2018-2023
Cardiovascular Institute Hospital
2018
Background: There is a lack of randomized controlled trial (RCT) data comparing outcomes different catheter-based interventions for intermediate-risk pulmonary embolism (PE). Methods: PEERLESS prospective, multicenter, RCT that enrolled 550 PE patients with right ventricular dilatation and additional clinical risk factors 1:1 to treatment large-bore mechanical thrombectomy (LBMT) or catheter-directed thrombolysis (CDT). The primary endpoint was hierarchal win ratio (WR) composite the...
Background: Bifemoral arterial access is common in patients undergoing transcatheter aortic valve implantation (TAVI), with a primary treatment (TAVI access) and secondary non-TAVI access. Pseudoaneurysm (PSA) an important complication of femoral puncture. Major vascular complications after TAVI are well described, but little known about PSA. Patients methods: A total 2063 underwent transfemoral between January 2014 2020. Vascular ultrasound the artery was assessed before TAVI. We compared...
Objective: High on-treatment platelet reactivity (HTPR) to dual antiplatelet therapy (DAPT) predicts adverse events in coronary artery disease patients. In peripheral (PAD) patients, data concerning the clinical impact of HTPR are limited. Therefore, we evaluated incidence (i) DAPT and (ii) its on 6 months outcome after angioplasty.Methods results: this prospective single center analysis, investigated 102 consecutive patients with PAD from 2016 2017. All underwent endovascular treatment due...
BACKGROUND: Recent research indicates that there is a high prevalence of heart failure with preserved ejection fraction in patients peripheral artery disease. We hypothesized endovascular treatment (EVT) flow-limiting stenosis improves left ventricular (LV) diastolic function. METHODS: Thirty symptomatic disease and according to Heart Failure Association−preserved score who were scheduled for EVT or angiography investigated at baseline, the day after (n=25) (control, n=5), 4 months...
Macrophages play a pivotal role in vascular inflammation and predict cardiovascular complications. Fluorine-19 magnetic resonance imaging (19F MRI) with intravenously applied perfluorocarbon allows background-free direct quantification of macrophage abundance experimental disease models mice. Recently, perfluorooctyl bromide-nanoemulsion (PFOB-NE) was to effectively image infiltration pig model myocardial infarction using clinical MRI scanners. In the present proof-of-concept approach, we...
Vascular access site-related complications are frequent in the context of transfemoral transcatheter aortic valve replacement (TAVR). The implantation a covered stent graft is an effective treatment option for bleeding control. However, external iliac and common femoral arteries exposed to flexion hip joint. Therefore, compression stent/strut fractures may occur, facilitating occlusion.In all 389 patients who received TAVR from 2013-2015 at Düsseldorf Heart Centre, we monitored management...
Was ist neu? Epidemiologie, Risikofaktoren, Screening und Sekundärprävention Die europäischen Fachgesellschaften der Kardiologen, Angiologen Gefäßchirurgen haben erstmals eine gemeinsame Leitlinie für die Diagnostik Therapie peripheren arteriellen Erkrankungen erarbeitet. Kooperation medizinischen Fachgruppen mündet in Empfehlung, multidisziplinäre „Vascular Teams“ zur Behandlung einzurichten, analog zu den „Heart Kardiologie Kardiochirurgie. Antithrombozytäre Erstmals wurde ein Kapitel...
Purpose . To report the effectiveness of left renal artery (LRA) occlusion using Amplatzer Vascular Plug (AVP) II as treatment for a high-flow arteriovenous fistula (RAVF) with multiple vein aneurysms (RVA) to prevent aneurysm rupture and cardiac decompensation. Case Report A 59-year-old female suffering from post-traumatic RAVF presented tachycardia increased output (CO). Doppler ultrasonography computed tomography (CT) scan revealed RVAs unilateral critically reduced kidney function....
Background Arterial hypertension affects cardiovascular outcome in patients with peripheral artery disease (PAD). We hypothesized that angioplasty of arterial stenoses decreases aortic (aBP) and brachial blood pressure (bBP). Methods Results In an index cohort (n=30), we simultaneously measured aBP, bBP, augmentation (AIx), pulse wave velocity (PWV) before after the iliac femoropopliteal arteries; diagnostic angiography served as a control. all-comer registry (n=381), prospectively bBP...
Femoral pseudoaneurysm (PSA) is a severe complication after endovascular procedures. Ultrasound-guided manual compression (MC) and percutaneous thrombin injection (TI) are frequently used treatments. MC less effective, TI may cause thromboembolic events.Up to date, there no data regarding impairment of microvascular tissue perfusion PSA treatment.In this single-center, prospective study 22 patients with were included. We compared macro- microcirculatory in the treated untreated leg at...
Data on the effect of transcatheter aortic valve implantation (TAVI) peripheral microcirculation are limited.
Managing chronic limb-threatening ischemia (CLTI) is challenging due to difficulties in assessing tissue oxygen saturation ulcers. Near-infrared spectroscopy (NIRS) a non-invasive method for measuring (StO
Background: The gold standard treatment for peripheral arterial disease (PAD) of the common femoral artery (CFA) is open endarterectomy (CFAE). Interest in less invasive endovascular (EVT) growing due to PAD patients’ frequent co-morbidities. Aims: We aimed evaluate three-year EVT outcomes multimorbid patients with severe calcified CFA lesions. Methods: Using prospectively maintained “all-comers” Duesseldorf PTA Registry, we analysed 150 CFA. Between January 2017 and October 2023, 66...
Background: The safety and efficacy of electrophysiological (EP) procedures using ultrasound (US) guidance are being increasingly studied. We investigated if a systematic workflow with (the US4ABL), comprising four steps (transesophageal echocardiography (TEE) for left atrial thrombus exclusion, US the groin vessels to guide femoral access, TEE-aided transseptal puncture, transthoracic (TTE) exclusion pericardial tamponade after procedure), reduces number complications fluoroscopy duration...
Abstract This case highlights the ECG interpretation in acute coronary syndrome absence from ST – elevation myocardial infarction. A patient with chest pain and biphasic T waves or deep inverted T‐ V2–V3 is at risk for Timely cardiological assessment angiography required.
Abstract Vascular complications (VCs) remain an important source of morbidity and mortality following percutaneous arterial catheterization. closure devices are popular frequently used, but sometimes cause vessel occlusions that may require vascular surgery or complex endovascular procedures. In this case report, we describe the retrieval embolized Angio‐Seal device causing acute limb ischemia in a severely diseased 75‐year‐old female patient. This highlights technique using snare catheter...