David Dexter

ORCID: 0000-0003-1366-3906
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About
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Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Central Venous Catheters and Hemodialysis
  • Vascular Procedures and Complications
  • Aortic aneurysm repair treatments
  • Peripheral Artery Disease Management
  • Diagnosis and Treatment of Venous Diseases
  • Aortic Disease and Treatment Approaches
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Infectious Aortic and Vascular Conditions
  • Coronary Interventions and Diagnostics
  • Intracranial Aneurysms: Treatment and Complications
  • Head and Neck Cancer Studies
  • Patient Satisfaction in Healthcare
  • Vascular anomalies and interventions
  • Dermatologic Treatments and Research
  • Dialysis and Renal Disease Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Peripheral Nerve Disorders
  • Atrial Fibrillation Management and Outcomes
  • Bariatric Surgery and Outcomes
  • Cardiovascular Health and Disease Prevention

Sentara Norfolk General Hospital
2020-2024

Eastern Virginia Medical School
2015-2024

Philips (United States)
2024

University of California, Los Angeles
2024

Old Dominion University
2024

Antalya IVF
2022

Jacksonville University
2022

Sentara Heart Hospital
2022

Urology of Virginia
2020

NYU Langone Health
2012-2013

Background: There is a lack of randomized controlled trial (RCT) data comparing outcomes different catheter-based interventions for intermediate-risk pulmonary embolism (PE). Methods: PEERLESS prospective, multicenter, RCT that enrolled 550 PE patients with right ventricular dilatation and additional clinical risk factors 1:1 to treatment large-bore mechanical thrombectomy (LBMT) or catheter-directed thrombolysis (CDT). The primary endpoint was hierarchal win ratio (WR) composite the...

10.1161/circulationaha.124.072364 article EN Circulation 2024-10-29

Background: Iliofemoral venous obstruction is recognized with increasing frequency as the underlying cause of lower extremity symptoms including edema, pain, skin changes, and, in advanced cases, ulceration. This study sought to evaluate safety and effectiveness Abre self-expanding stent system for treatment symptomatic iliofemoral outflow obstruction. Methods: The ABRE Study (A Multi-Center, Non-Randomized Evaluate Safety Effectiveness Venous Self-Expanding Stent System Patients With...

10.1161/circinterventions.121.010960 article EN cc-by-nc-nd Circulation Cardiovascular Interventions 2022-02-01

<h2>Abstract</h2><h3>Objectives</h3> The multicenter, prospective, single arm CLOUT registry assesses the safety and effectiveness of ClotTriever System (Inari Medical, Irvine, CA) for treatment acute nonacute lower extremity deep vein thrombosis (DVT) in all-comer patients. Reported here are outcomes first 250 <h3>Methods</h3> All-comer patients with DVT were enrolled, including those bilateral DVT, previously failed treatment, regardless symptom duration. primary end point is complete or...

10.1016/j.jvsv.2022.02.013 article EN publisher-specific-oa Journal of Vascular Surgery Venous and Lymphatic Disorders 2022-02-24

To report the first interim analysis of STRIKE-PE study, evaluating safety and effectiveness computer assisted vaccum thrombectomy (CAVT) for treatment acute pulmonary embolism (PE). This prospective, international, multicenter study will enroll 600 adult patients with PE ≤14 days a right ventricle (RV)-to-left (LV) ratio ≥0.9 who receive first-line endovascular CAVT using Indigo Aspiration System (Penumbra, Alameda, California). Primary endpoints are change in RV/LV incidence composite...

10.1016/j.jvir.2024.04.028 article EN cc-by-nc-nd Journal of Vascular and Interventional Radiology 2024-05-09

Purpose To report 36-month outcomes and subgroup analysis of the ABRE Study evaluating safety effectiveness Abre venous self-expanding stent system for treatment symptomatic iliofemoral outflow obstruction disease. Methods The was a prospective, multicenter, non-randomized study that enrolled implanted stents in 200 participants (mean age 51.5±15.9 years 66.5% women) with at 24 global sites. Outcomes assessed through 36 months included patency, major adverse events, migration, fracture,...

10.1016/j.jvir.2024.01.030 article EN cc-by Journal of Vascular and Interventional Radiology 2024-02-08

BackgroundWe report in-hospital outcomes from the multicenter, prospective, single-arm ClotTriever Outcomes (CLOUT) registry, which enrolled up to 500 patients with proximal lower extremity deep vein thrombosis (DVT) treated percutaneous mechanical thrombectomy using System (Inari Medical).MethodsThe CLOUT registry all-comer DVT, irrespective of symptom duration, thrombus age, prior treatment current or bilateral thrombus. The primary effectiveness end point was defined as complete near...

10.1016/j.jscai.2023.100585 article EN cc-by Journal of the Society for Cardiovascular Angiography & Interventions 2023-02-22

Abstract Purpose Mechanical thrombectomy for the treatment of deep vein thrombosis (DVT) is being increasingly utilized to reduce symptoms and prevent postthrombotic syndrome (PTS), but more data on clinical outcomes are needed. was studied in ClotTriever Outcomes (CLOUT) registry with 6-month full analysis reported herein. Materials Methods The CLOUT a prospective, all-comer study that enrolled 500 lower extremity DVT patients across 43 US sites treated mechanical using System. Core-lab...

10.1007/s00270-023-03509-8 article EN cc-by CardioVascular and Interventional Radiology 2023-08-14

ObjectiveTo compare the comparative effects of treatment with contemporary mechanical thrombectomy or anticoagulation on Villalta scores and post thrombotic syndrome incidence through 12 months in iliofemoral deep vein thrombosis.MethodsPatients thrombosis Acute Venous Thrombosis: Thrombus Removal Adjunctive Catheter-Directed Thrombolysis (ATTRACT) randomized trial ClotTriever Outcomes (CLOUT) registry were included this analysis. Both studies evaluated thrombus removal syndrome. Patients...

10.1016/j.jvsv.2024.101825 article EN cc-by-nc-nd Journal of Vascular Surgery Venous and Lymphatic Disorders 2024-01-24

The all-comer ClotTriever Outcomes registry assessed indicators of thrombus chronicity in patients with acute, subacute, and chronic lower extremity deep vein thrombosis (DVT). effectiveness the System (Inari Medical, Irvine, CA) by subgroup was also reported here this subanalysis.All-comer DVT were enrolled, no limitation based on patients' symptom duration. Chronicity three times compared: before procedure duration, during available pre-thrombectomy imaging, visual inspection extracted...

10.1016/j.jvsv.2022.04.015 article EN publisher-specific-oa Journal of Vascular Surgery Venous and Lymphatic Disorders 2022-06-14

Mechanical thrombectomy is a promising treatment option for deep vein thrombosis; however, long-term data are lacking. Here, we report the first time 1-year clinical outcomes from completely enrolled ClotTriever Outcomes (CLOUT) registry evaluating mechanical with System (Inari Medical).

10.1016/j.jscai.2024.101307 article EN cc-by-nc-nd Journal of the Society for Cardiovascular Angiography & Interventions 2024-02-15

Objective Compare thrombus removal and residual venous symptoms signs of disease following interventional treatment iliofemoral deep vein thrombosis (DVT) with mechanical thrombectomy (MT) pharmacomechanical catheter directed thrombolysis (PCDT). Methods Retrospective cohort analysis propensity score matched subgroups from the multicentre prospective MT ClotTriever Outcomes registry PCDT arm randomised Acute Venous Thrombosis: Thrombus Removal Adjunctive Catheter-Directed Thrombolysis trial....

10.1016/j.ejvs.2023.11.017 article EN cc-by-nc-nd European Journal of Vascular and Endovascular Surgery 2023-11-21

Abstract Background Right heart strain is assessed by using right ventricular (RV)/left (LV) ratio as a surrogate performance measure. Other echocardiographic measures of function are available, although they more commonly used prognostically. Altogether, these can be to indicate alleviation and effectiveness pulmonary embolism (PE) treatment. Purpose This subgroup interim analysis from the first 300 patients in STRIKE-PE study reports periprocedural clinical results after treatment PE with...

10.1093/ehjacc/zuaf044.209 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Objective Acute limb ischemia is associated with high rates of amputation and consequent morbidity mortality. The objective this study to report on the safety efficacy aspiration thrombectomy using Indigo® Aspiration System in patients lower extremity acute (LE-ALI). Methods STRIDE was an international, multicenter, prospective, that enrolled 119 participants presenting LE-ALI. Patients were treated firstline mechanical System, prior stenting or angioplasty, other therapies as determined by...

10.1016/j.jvs.2023.10.062 article EN cc-by-nc-nd Journal of Vascular Surgery 2023-11-04

To compare thrombus removal and residual venous symptoms signs of disease following interventional treatment iliofemoral deep vein thrombosis (DVT) with mechanical thrombectomy (MT) pharmacomechanical catheter directed thrombolysis (PCDT).

10.1016/j.jvs.2024.04.013 article EN other-oa Journal of Vascular Surgery 2024-05-20

Background Postthrombotic syndrome is a common complication of deep vein thrombosis, with limited treatment options. Methods and Results ACCESS PTS (Accelerated Thrombolysis for Post-Thrombotic Syndrome Using the Acoustic Pulse Ekosonic Endovascular System) multicenter, single-arm, prospective study evaluating patients chronic thrombosis postthrombotic (Villalta score ≥8) who received minimum 3 months anticoagulation. Patients underwent percutaneous transluminal venoplasty...

10.1161/jaha.119.013398 article EN cc-by-nc-nd Journal of the American Heart Association 2020-01-25
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