A5032129878- Action Observation and Synchronization
- Psychosomatic Disorders and Their Treatments
- Obsessive-Compulsive Spectrum Disorders
- Schizophrenia research and treatment
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Biofield Effects and Biophysics
- Neural and Behavioral Psychology Studies
- Virtual Reality Applications and Impacts
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Hearing Impairment and Communication
- Spatial Cognition and Navigation
- Motor Control and Adaptation
- Categorization, perception, and language
- Photovoltaic Systems and Sustainability
- Visual perception and processing mechanisms
- Suicide and Self-Harm Studies
- Diabetes Management and Education
- Botulinum Toxin and Related Neurological Disorders
- Neuroscience and Music Perception
- Augmented Reality Applications
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Hemispheric Asymmetry in Neuroscience
- Transcranial Magnetic Stimulation Studies
University of Bern
2020-2025
University College London
2023
Ministry of Health
2023
Max Planck Institute for Biological Cybernetics
2018-2022
University Hospital of Bern
2021
University of the Aegean
2020
Translational Research Institute
2020
Aix-Marseille Université
2017-2019
Centre National de la Recherche Scientifique
2017-2019
Max Planck Society
2018
Up to 50% of patients with schizophrenia are suffering from motor abnormalities, which may contribute decreased quality life, impaired work capacity, and a reduced life expectancy by 10-20 years. However, the effect abnormalities on social global functioning, as well as, functional capacity is not clear. We hypothesized, that presence associated poorer outcomes in schizophrenia.We collected data 5 different 156 spectrum disorders: parkinsonism, catatonia, dyskinesia, neurological soft signs...
Abstract Background and Hypothesis Formal thought disorder (FTD) is a core symptom of psychosis, but its neural correlates remain poorly understood. This study tested whether four FTD dimensions differ in their association with brain perfusion structure. Study Design cross-sectional investigated 110 patients schizophrenia spectrum disorders using 3T magnetic resonance imaging (MRI). The Thought Language Disorder scale (TALD) was utilized, which comprises subscales: Objective Positive (OP),...
Motor abnormalities are highly prevalent among patients with schizophrenia spectrum disorders. Very likely, motor control processes, such as dexterity and grip force (GF), impaired in schizophrenia. We aimed to explore associations between various processes investigate whether specific predict the performance of fine movements GF. Our analyses included 198 applied well-established standardized rating scales assess five different abnormalities: psychomotor slowing (PS), neurological soft...
Abstract Neuronal oscillations refer to periodic changes of neuronal activity. A prominent oscillation, especially in sensorimotor areas, is the beta-frequency-band (∼ 13–29 Hz). Sensorimotor beta are predominantly linked motor-related functions such as preparation and/or execution movements. In addition, have been suggested play a role long-range communication between multiple brain areas. this review, we assess different studies that show additionally involved visual perception and imagery...
Individuals with depression exhibit numerous interpersonal deficits. As effective use of gestures is critical for social communication, it possible that depressed individuals' deficits may be due to in gesture performance. The present study thus compared performance patients and controls examined whether these relate cognitive other domains dysfunction.Gesture was evaluated 30 using the Test Upper Limb Apraxia (TULIA). Clinical rating scales were assessed determine if associated motor, or...
The cortical network for action observation includes areas of the visual cortex and non-visual areas, including motoric system. Parts this are known their contralateral organization during motion execution, i.e., they predominantly control respond to movements body side. We were interested whether lateralized was also present observation. Human participants viewed point-light displays human actors, where actor facing moving either right or left, while participants' neuromagnetic activity...
Movement abnormalities are prevalent across all stages of schizophrenia contributing to poor social functioning and reduced quality life. To date, treatments scarce, often involving pharmacological agents, but none have been shown improve movement effectively. Virtual reality (VR) is a tool used simulate virtual environments where behavioral performance can be quantified safely different tasks while exerting control over stimulus delivery, feedback measurement in real time. Sensory...
Several studies have shown activation of the mirror neuron system (MNS), comprising temporal, posterior parietal, and sensorimotor areas when observing plausible actions, but far less is known on how these cortical interact during recognition a action. Here, we recorded neural activity with magnetoencephalography while subjects viewed point‐light displays biologically scrambled versions actions. We were interested in modulations oscillatory and, specifically, coupling between visual motor...
Arterial Spin Labeling is a valuable functional imaging tool for both clinical and research purposes. However, little known about the test-retest reliability of cerebral blood flow measurements over longer periods. In this study, we investigated pulsed in assessing 3 (n=28) vs 8 (n=19) weeks interscan interval 47 healthy participants. As measure reliability, calculated voxel-wise, whole-brain, regions interest intraclass correlation coefficients. The whole-brain mean resting-state showed...
Renewable energy technologies like photovoltaics may be considered an indispensable component of a low-carbon electricity mix, but social acceptance should not taken for granted. For instance, in Greece there are still claims, especially rural areas, regarding the land use and competition against more traditional economic activities such as grazing. An argument favor confining to roof-mounted photovoltaic installations is additional infrastructure requirements ground-mounted larger-scale...
Gestures are an important part of communication. Patients with schizophrenia present gesture deficits that tend to deteriorate in the course disease and hamper functional outcome. This deficit has been associated motor abnormalities, cognitive impairment, psychotic symptoms. Unaffected, first-degree relatives patients share some subclinical abnormalities. We aimed investigate, whether performance changes symptomatic improvement patients, test longitudinal unaffected, relatives. In this...
Nonverbal social perception is the ability to interpret intentions and dispositions of others by evaluating cues such as facial expressions, body movements, emotional prosody. plays a key role in cognition fundamental for successful interactions. Patients with schizophrenia have severe impairments nonverbal leading isolation withdrawal. Collectively, these aforementioned deficits affect patients' quality life. Here, we compare patients controls examine how relates daily functioning.
An important component of nonverbal communication is gesture performance, which strongly impaired in 2/3 patients with schizophrenia. Gesture deficits schizophrenia are linked to poor social functioning and reduced quality life. Therefore, interventions that can help alleviate these crucial. Here, we describe an ongoing randomized, double-blind 3-arm, sham-controlled trial combines two reduce patients. The combined continuous theta burst stimulation (cTBS) cognitive remediation therapy...
Gesture deficits are ubiquitous in schizophrenia patients contributing to poor social communication and functional outcome. Given the dynamic nature of communications, current study aimed explore underlying socio-cognitive processes associated with point-light-displays (PLDs) communicative gestures absence any other confounding visual characteristics, compare them well-established stimuli such as pictures by examining their association symptom severity motor-cognitive modalities.We included...
Data was collected using standard communication equipment and invoices provided by an established civil construction renewable energy development operation company. referring to the construction, costings, environmental impacts of a photovoltaic farm were recorded into four distinct Excel files namely: i) Project Management Data, ii) Life Cycle Inventory (LCI), iii) Electricity Generation iv) Operational Cost Data. For project management, given quantities resources used in each activity...
Gesture performance deficits are prevalent in schizophrenia patients and strongly associated with poor social communication skills community functioning, affecting their overall quality of life. Currently, video-recording technology is widely used clinical settings to assess gesture production patients. Nevertheless, the subjective evaluation video-recordings can encumber task assessment. The present study will aim use virtual reality examine its potential as an alternative tool objectively...
Virtual Reality supports collaboration among partners across departments and fields, independent of physical boundaries. reality applications can solve the time cost consuming logistic problem that companies encounter when sending experts to remote locations. However, it is not yet clear how effective collaborate in In one experiment, we examined whether who are physically same room interact with each other before they start collaborating affects performance compared collaborators meet only...
Disorders of mental health are major risk factors for suicidal behavior and require adequate treatment. However, the effect psychotropic medication on is unclear. The 120 participants in a randomized clinical trial brief therapy suicide attempters (Attempted Suicide Short Intervention Program, ASSIP) reported repeated attempts, ideation, depression, treatment as usual (TAU), at baseline, 6, 12, 18, 24 months follow-up. RCT had no influence prescribed. Drugs prescribed were categorized any...
We investigated whether gravitational constraints influence the interaction of visual, proprioceptive and vestibular cues for Biological Motion Perception (BMP). Participants were asked to distinguish between plausible random point-light movements, while passively placed in either an upright or a tilted body orientation. Manipulating orientation with respect gravity leads different signals transmitted by proprioceptive, systems. overall faster distinguishing movements than movements....
Abstract Background and Hypothesis Abnormal psychomotor behavior is a core schizophrenia symptom. However, assessment of motor abnormalities with expert rating scales challenging. The Positive Negative Syndrome Scale (PANSS) includes 3 items broadly related to hypokinetic behavior. Here, we tested whether sum score the PANSS mannerisms posturing (G5), retardation (G7), disturbance volition (G13) corresponds ratings, potentially qualifying as proxy-marker abnormalities. Study Design Combining...