A5112529051- Geological and Geochemical Analysis
- Geochemistry and Geologic Mapping
- earthquake and tectonic studies
- High-pressure geophysics and materials
- Geochemistry and Elemental Analysis
- Health disparities and outcomes
- Hydrocarbon exploration and reservoir analysis
- Cervical Cancer and HPV Research
- Brucella: diagnosis, epidemiology, treatment
- Nutritional Studies and Diet
- Geochemistry and Geochronology of Asian Mineral Deposits
- Mental Health Treatment and Access
- Adenosine and Purinergic Signaling
- Molecular Biology Techniques and Applications
- Immune cells in cancer
- Healthcare Systems and Reforms
- Burkholderia infections and melioidosis
- Immunotherapy and Immune Responses
- Nanoplatforms for cancer theranostics
- Health, psychology, and well-being
- Hepatitis B Virus Studies
- Animal Diversity and Health Studies
- Atherosclerosis and Cardiovascular Diseases
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
Institute of Geology and Geophysics
2014-2024
Chinese Academy of Sciences
2014-2024
University of Chinese Academy of Sciences
2016-2024
Wuhan University of Science and Technology
2024
Shandong University
2020-2024
National Health and Family Planning Commission
2022-2024
Guizhou Provincial People's Hospital
2021-2024
Jiangsu University
2022-2024
Xuzhou Cancer Hospital
2022-2024
Northwestern Polytechnical University
2022-2024
Glioblastoma (GBM), the most common subtype of malignant gliomas, is characterized by aggressive infiltration, high malignancy, and poor prognosis. The frustrating anti-GBM outcome conventional therapeutics due to immunosuppressive milieu, in addition formidable obstacle blood-brain barrier (BBB). Combination therapy with an immune checkpoint blockade (ICB) has emerged as a critical component treatment GBM. Here, we report engineered macrophage-membrane-coated nanoplatform enhanced...
Background There is a growing acknowledgment of the potential influence antioxidative effects resulting from dietary decisions on occurrence stroke. The objective this study was to elucidate correlation between composite antioxidant index (CDAI) and incidence stroke in general population United States. Methods We gathered cross-sectional data encompassing 40,320 participants National Health Nutrition Examination Survey (NHANES) spanning years 1999 2018. Employing weighted multivariate...
Bayan Obo ore deposit is the largest rare-earth element (REE) resource, and second niobium (Nb) resource in world. Due to complicated element/mineral compositions involving several geological events, REE enrichment mechanism genesis of this giant still remains intense debated. The hosted massive dolomite, nearly one hundred carbonatite dykes occur vicinity deposit. can be divided into three types from early late: co-existing dolomite-calcite calcite type, corresponding different evolutionary...
Indoleamine 2,3-dioxygenase (IDO-1) is emerging as an important new therapeutic target for the treatment of cancer, neurological disorders, and other diseases that are characterized by pathological tryptophan metabolism. However, only a few structural classes known to be IDO-1 inhibitors. In this study, natural compound tryptanthrin was discovered novel potent inhibitor screening indole-based structures. Three series 13 derivatives were synthesized, structure–activity analysis undertaken....
Microplastics (< 5 mm diameter) are one of most important environmental pollutants and contaminants worldwide. However, how microplastics affect liver immune microenvironment in not well understood. (0.5 µm) were administered orally to C57BL/6J mice for 4 consecutive weeks at the rate 0.5 mg/day. Non-parenchymal cells isolated from through fractionation fresh hepatic tissues. The landscape four cell populations B cells, T NK macrophages tissues was then evaluated using flow cytometry....
Abstract Background There is a dearth of research combining geographical big data on medical resource allocation and growth with various statistical data. Given the recent achievements China in economic development healthcare, this study takes as an example to investigate dynamic distribution patterns resources, utilizing healthcare resources from 290 cities China, well population-related The aims examine correlation between spatial ultimate goal providing evidence for promoting global...
Gold ores of the Qiyugou deposit in eastern part Xiong'ershan region are hosted breccia pipes within a Mesozoic granitic porphyry. Three stages hydrothermal alteration activity recognized breccias. The first stage metasomatism produced extensive K-feldspar alteration. second is associated with deposition gold and base metal sulphides. third defined by fine quartz–calcite ± pyrite veinlets containing minor gold. Four types fluid inclusions present quartz calcite matrix veins. Type I...
Abstract The S anshandao gold deposit, located at northwestern edge of the J iaodong P eninsula, eastern N orth C hina raton, is one largest deposits in province. In disseminated‐ and stockwork‐style ores are hosted M esozoic granitoids. Mineralization alteration largely controlled by regional anshandao– angshang fault. Sericite separated from rocks mineralized zone yields an Rb–Sr isochron age 117.6 ± 3.0 Ma. ore‐forming fluids deposit contain CO 2 ‐H O‐NaCl±CH 4 with low to intermediate...
The rate of brucellosis, a zoonotic disease, has rapidly increased in humans brucellosis(HB) recent years. In 1950-2018, total 684,380 HB cases (median 2274/year (interquartile range (IQR) 966-8325)) were reported to the National Infectious Disease Surveillance System mainland China. incidence peaked 2014 (4.32/100,000), and then showed downward trend; we predict that it will maintain steady trend 2019-2020. Since 2015, shown opposite trends north south China; rates have fallen increased....
Concerns about vaccine safety are an important reason for hesitancy, however, limited information is available on whether common adverse reactions following vaccination affect the immune response. Data from three clinical trials of recombinant vaccines were used in this post hoc analysis to assess correlation between inflammation-related solicited (ISARs, including local pain, redness, swelling or induration and systematic fever) responses after vaccination. In phase III trial bivalent...