A5001320420- Hematopoietic Stem Cell Transplantation
- Pharmaceutical Practices and Patient Outcomes
- Innovations in Medical Education
- Acute Lymphoblastic Leukemia research
- Multiple Myeloma Research and Treatments
- Renal Transplantation Outcomes and Treatments
- Polyomavirus and related diseases
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Health Sciences Research and Education
- Medication Adherence and Compliance
- Neutropenia and Cancer Infections
- Pharmacological Effects and Toxicity Studies
- Parvovirus B19 Infection Studies
- Medical Education and Admissions
- Cancer Treatment and Pharmacology
- Diabetes Treatment and Management
- Global Health Workforce Issues
- HIV/AIDS drug development and treatment
- Healthcare professionals’ stress and burnout
- Eosinophilic Disorders and Syndromes
- Health and Medical Research Impacts
- Diabetes Management and Research
- Problem and Project Based Learning
University of North Carolina Hospitals
2007-2024
University of North Carolina at Chapel Hill
2011-2023
University of North Carolina Health Care
2011-2019
UNC Lineberger Comprehensive Cancer Center
2015-2016
Indiana University School of Medicine
2012-2016
University School
2012
Indiana University
2012
American Society of Clinical Oncology
2011
Lahey Hospital and Medical Center
2011
Memorial Sloan Kettering Cancer Center
2011
<h3>Objective.</h3> —To determine whether optimized glycemic control in type I diabetic recipients of renal allografts will prevent or delay lesions the allograft. <h3>Design.</h3> —Prospective, controlled, and randomized trial an inception cohort allograft recipients. The experimental group underwent maximized control, standard was treated same way as other patients transplant clinic. Patients baseline (before transplant) 5-year posttransplant biopsies. <h3>Setting.</h3> —University...
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The novel coronavirus identified in 2019 (COVID-19) pandemic has impacted pharmacy graduate and postgraduate education. This crisis resulted a cosmic shift the administration of these programs to ensure core values are sustained. Adjustments may be needed at minimum that trainees complete program requirements while maintaining safety. Moving forward, additional issues arise will need addressed such as admissions onboarding, acclimating students new training environments, managing inadequate...
PURPOSE To test the hypothesis that progression of androgen sensitive prostate cancer is dependent on growth factors, such as platelet derived factor (PDGF), and inhibition PDGF receptor (PDGF-R) with imatinib will induce anti-tumor activity. PATIENTS AND METHODS This phase II study evaluated in patients specific antigen (PSA) after local therapy. Patients received 400 mg orally twice a day for 24 weeks (six cycles). were monitored every 4 an effect PSA toxicity. Immunohistochemistry (IHC)...
The optimal mobilization strategy prior to autologous stem cell transplantation for patients with multiple myeloma remains unclear. Mobilization cytokines alone appears yield suboptimal results in older as well who have received lenalidomide. To avoid the marked cytopenias and risks of hemorrhagic cystitis associated administration cyclophosphamide, we investigated efficacy safety chemomobilization an intermediate dose etoposide (VP-16; 375 mg/m(2) on days +1 +2) granulocyte-colony...
The outcomes of a patient-centered layered learning practice model (LLPM) in which the clinical specialist acted as attending pharmacist and managed pharmacy team to provide direct patient care were evaluated.Two 30-day evaluations conducted on acute malignant hematology medical oncology services University North Carolina Medical Center 2011. primary objective this study was design an LLPM that used expand offered. outcome frequency encounters at discharge (medication reconciliation...
Purpose: The American Society of Health-System Pharmacists (ASHP) requires that accredited residency programs provide pharmacy residents the opportunity to perform a practice-based project. objective this study was evaluate impact research training on residents’ actual versus perceived ability solve practice-related problems in their professional careers. Methods: This cross-sectional surveyed postgraduate year 1 (PGY1) practice who completed at large academic medical center between 2007 and...
Tacrolimus exhibits high inter-patient pharmacokinetics (PK) variability, as well a narrow therapeutic index, and therefore requires drug monitoring. Germline mutations in cytochrome P450 isoforms 4 5 genes (CYP3A4/5) the ATP-binding cassette B1 gene (ABCB1) may contribute to interindividual tacrolimus PK which impact clinical outcomes among allogeneic hematopoietic stem cell transplantation (HSCT) patients. In this study, 252 adult patients who received for acute graft versus host disease...
The movement to deliver cancer care in resource-limited settings is gaining momentum, with particular emphasis on the creation of cost-effective, rational algorithms utilizing affordable chemotherapeutics treat curable disease. delivery resource-replete a concerted effort by team multidisciplinary providers. oncology pharmacy, which now considered integral resourced medical practice, developed over last several decades an limit healthcare provider exposure workplace hazards and risk...
Abstract Purpose The attainment of fundamental research skills to create and disseminate new knowledge is imperative for the advancement pharmacy practice. Research training an important component postgraduate residency training; however, traditional model performing has several limitations that have hindered ability residents complete high-quality projects. Therefore, our institution developed implemented flipped with 2013–2014 practice class. Summary modifies timeline better align...
This study seeks to evaluate the impact of pharmacists' involvement in care patients undergoing bone marrow transplantation (BMT).This was a three-phase study. In phase 1, inpatient and outpatient pharmacist encounters were totaled services provided translated revenue generated from prescription billing charges. 2, activities interventions associated with time savings estimated by providers. 3, providers surveyed assess their expectations, experiences, value perceptions pharmacists.A...
Rao, K. V.; Sutherland, D.; Kjellstrand, C. M.; Najarian, J. S.; Shapiro, F. L. Author Information
Abstract Introduction Hospital departments of pharmacy are experiencing significant challenges in the recruitment and retention trained hematology‐oncology pharmacists. The reasons for these varied, but one consistent challenge is growing attrition clinically‐trained pharmacists from patient care environment. Methods An electronic 21‐item survey was distributed to oncology across United States. assessed work environment, board certification, clinical commitment, other factors. How those...
Autologous stem cell transplantation remains a mainstay of therapy for diseases such as multiple myeloma and relapsed lymphoma. The use plerixafor has been shown to augment the ability collect adequate cells, but optimal this agent when used with chemotherapy is not yet clear. We utilized an algorithm-based approach addition 54 patients undergoing chemomobilization reduced-dose etoposide who had less than preapheresis CD34+ count. precount 20 cells/μL threshold initiate apheresis....
Abstract Introduction Hematology/oncology pharmacists work in various roles healthcare systems and represent a highly skilled valuable resource. There remains significant challenge the recruitment retention of these well‐trained pharmacists. We sought to identify key factors propose solutions impact ability recruit, promote, retain Methods An initial survey 2021 assessed status oncology pharmacist workforce with regard job satisfaction attrition risk. Based on top 5 identified Initial...