A5100343812- Genetics, Bioinformatics, and Biomedical Research
- Bioactive Natural Diterpenoids Research
- Metabolomics and Mass Spectrometry Studies
- Plant-based Medicinal Research
- Mycobacterium research and diagnosis
- Pharmacological Effects of Natural Compounds
- Inflammatory Bowel Disease
- Bacteriophages and microbial interactions
- Ecology and Conservation Studies
- Protein Degradation and Inhibitors
- Antimicrobial Peptides and Activities
- Essential Oils and Antimicrobial Activity
- Circular RNAs in diseases
- Advancements in Transdermal Drug Delivery
- CAR-T cell therapy research
- Antibiotic Resistance in Bacteria
- Phytochemistry and Biological Activities
- Escherichia coli research studies
- MicroRNA in disease regulation
- Signaling Pathways in Disease
- Water Quality Monitoring and Analysis
- Alkaloids: synthesis and pharmacology
- Medicinal Plants and Bioactive Compounds
- Heat shock proteins research
- Plant-derived Lignans Synthesis and Bioactivity
Shanghai University of Traditional Chinese Medicine
2000-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Southwest Petroleum University
2024
Zhejiang Wanli University
2023
Ocean University of China
2023
State Forestry and Grassland Administration
2022
Xinjiang Medical University
2022
State Key Laboratory of Chemobiosensing and Chemometrics
2022
Background: Curcumin has been proved to have promising prospects in the fields of anti-inflammation, antibacterial, anti-oxidation, and neuroprotection. However, its poor water solubility stability strong acid, as well fast metabolism, lead low bioavailability, making it difficult develop further. This study aimed improve bioavailability curcumin by using microfluidic preparation technology. Methods: Using a self-built system, polyvinylpyrrolidone K30 sodium dodecyl sulfate were used...
Rhodojaponin III (RJ-III) is a bioactive diterpenoid, which mainly found in Rhododendron molle G. Don (Ericaceae), potent analgesia traditional Chinese medicine with several years of clinical applications the country. However, its use limited by acute toxicity and poor pharmacokinetic profiles. To reduce such limitations, current study incorporated RJ-III into colloidal drug delivery system hydroxypropyl trimethyl ammonium chloride chitosan (HACC)-modified solid lipid nanoparticles (SLNs) to...
Abstract Acne caused by inflammation of hair follicles and sebaceous glands is a common chronic skin disease. Arctigenin (ATG) an extract Arctium lappa L., which has significant anti‐inflammatory effects. However, the effect mechanism ATG in cutaneous mediated Cutibacterium acnes ( C . ) not been fully evaluated. The purpose this study was to explore potential treatment acne through network pharmacology experimental confirmation. An model established injected live C. into living mice treated...
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that presents significant treatment challenges due to its complexity, especially in terms of the various side effects traditional medications may bring during course disease. Traditional Chinese medicine (TCM) has emerged as promising complementary therapy for UC. Based on latest research, our editorial explored current issues and potential essential research directions TCM treating We anticipate future high-quality will pave...
Background: Rhodojaponin III (RJ-III), a characteristic diterpene of Rhododendron molle G. Don, has wide range pharmacological activities including anti-inflammatory, antihypertensive, and analgesic effects. However, further research development have been limited because its intense acute toxicity poor pharmacokinetic profile. Objective: In this study, we propose the construction folic acid–conjugated mesoporous silica nanoparticles (FA-MSNs) as carriers to deliver RJ-III in an attempt...
Aims:The habitat selection of animals is a scale-dependent ecological process, affected by environmental factors across spatial scales.Studying key which influence both and temporal scales tantamount to comprehensive understanding species' resource requirements effective protection.Chinese monal (Lophophorus lhuysii), an alpine-obligate Galliformes species native China, has received first-class National Protected Wildlife status with high priority for global conservation.To our knowledge, no...
Objective. The objective is to explore the action and mechanism of circ_0109046 on malignant phenotypes ovarian cancer cells. Methods. Circ_0109046 miR-338-3p expression were detected by quantitative real-time polymerase chain reaction (qRT-PCR). In vitro assays conducted investigate cell growth metastasis. Western blotting was utilized contents apoptosis-related markers. binding between validated using dual-luciferase reporter assay. Results. increased, while content decreased in tissues....
Abstract How miRNAs play a role in collateral formation of chronic total occlusion (CTO) patients and predicting myocardial perfusion has not been investigated. In this study, we screened circulating CTO stable coronary artery disease using high-throughput sequencing found 42 differential expressed miRNAs, including miR-329, miR-494 miR-495, which belong to 14q32 gene cluster. The down regulation miR-495 was confirmed an independently larger cohort. Then vitro vivo demonstrated that...