A5101484582- Colorectal Cancer Surgical Treatments
- Speech Recognition and Synthesis
- Colorectal and Anal Carcinomas
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Colorectal Cancer Screening and Detection
- Cardiovascular Function and Risk Factors
- Gastric Cancer Management and Outcomes
- Cancer-related molecular mechanisms research
- Natural Language Processing Techniques
- Speech and Audio Processing
- Cardiac Fibrosis and Remodeling
- Liver Disease Diagnosis and Treatment
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Treatments and Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Music and Audio Processing
- Congenital heart defects research
- Adipose Tissue and Metabolism
- Pancreatic and Hepatic Oncology Research
- Phytochemical and Pharmacological Studies
- Endoplasmic Reticulum Stress and Disease
- Connective tissue disorders research
- Hepatocellular Carcinoma Treatment and Prognosis
- Protein Tyrosine Phosphatases
Lanzhou University
2024-2025
Gansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research
2025
First Hospital of Lanzhou University
2025
Kangwon National University
2025
Huazhong University of Science and Technology
2024
First Affiliated Hospital of Zhengzhou University
2016-2024
Aerospace Information Research Institute
2024
Chinese Academy of Sciences
2024
Gansu Provincial Hospital
2009-2024
Zhengzhou Children's Hospital
2023
ZnO/ZnS/CdS/CuInS2 core-shell nanowire arrays with enhanced photoelectrochemical activity under visible light were successfully prepared via ion exchange and hydrothermal methods. The samples characterized by X-ray diffraction, scanning electron microscopy, transmission UV-vis absorption, photoemission spectroscopy, response. As a p-n junction photoanode, heterostructure shows much higher photoelectrocatalytic toward water splitting than ZnO/ZnS/CdS ZnO/ZnS films. film optimal constitution...
Background/Aims: Vascular smooth muscle cell (VSMC) hyperplasia plays important roles in the pathogenesis of many vascular diseases, such as atherosclerosis and restenosis.Many microRNAs (miRs) have recently been reported to regulate proliferation migration VSMC.In current study, we aimed explore function miR-93 VSMCs its molecular mechanism.Methods: First, qRT-PCR immunofluorescence assays were performed determine expression rat following carotid artery injury vivo platelet-derived growth...
Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic worldwide. Due to growing economic burden NAFLD on public health, it an emergent target for clinical intervention. DUSP12 is a member dual specificity phosphatase (DUSP) family, which plays important roles in brown adipocyte differentiation, microbial infection, and cardiac hypertrophy. However, role yet be clarified. Here, we reveal that protects against hepatic steatosis inflammation L02 cells after...
With regards to colon cancer, resistance 5‑fluorouracil (5‑FU)‑based chemotherapy and cancer stem cells (CSCs) are considered important factors underlying therapy failure. Metastasis‑associated 1 (MACC1) has been associated with poor prognosis the promotion of metastasis within several types cancer. However, biological behavior MACC1 in chemoresistance CSC‑like properties remains unclear. In present study, various methods including gene knockdown, overexpression, western blotting,...
The 19th century was an important period in Western music history, yet the contributions of female composers during this time have often been overlooked. This paper aims to explore historical background, social perceptions, and status influence world century. study finds that societal cultural constraints, as well a lack resources education, significantly impacted creative opportunities for composers. However, despite these challenges, such Clara Schumann Marie Camille Saint-Saëns...
Bel Canto vocal performance, as an important form of musical expression, plays irreplaceable role in music education. Its historical roots can be traced back to the 18th century. After multiple stages development, it formed a unique artistic style and teaching philosophy. This paper aims explore application education, including its principles, enhancement students' literacy, curriculum design practice. The research shows that not only promotes improvement techniques expressiveness, but also...
Human epidermal growth factor receptor 2 (HER2) is an anti-cancer drug target for colon cancer. Among patients with colorectal malignancy (colorectal cancer, CRC), those HER2 mutations have a poor overall prognosis and significantly increased resistance. In recent years, anti-HER2 therapeutic drugs developed rapidly. According to several clinical studies case reports, therapy, as emerging approach, plays crucial role in the treatment of HER2-positive CRC patients. Here, we present descending...
The role of hepatic resection in hepatocellular carcinoma (HCC) with accompanying portal vein tumor thrombus (PVTT) remains controversial. This study aimed to evaluate the surgical outcomes compared those transarterial chemoembolization (TACE) HCC patients. A retrospective was conducted using medical records 230 patients invasion who underwent (96 patients) or TACE (134 patients). baseline characteristics, clinicopathological parameters, and overall survival rates were between 2 groups....
Microfibril-associated protein 2 (MFAP2) is an extracellular matrix that interacts with fibrillin to modulate the function of microfibrils. MFAP2 has been reported play a significant role in obesity, diabetes, and osteopenia, shown be upregulated head neck squamous cell carcinoma. However, molecular prognostic value have never gastric cancer (GC) or any other tumors.The current study investigated expression patterns, significance, functional role, possible mechanisms GC.We demonstrated was...
Abstract miR‐222 participates in many cardiovascular diseases, but its effect on cardiac remodeling induced by diabetes is unclear. This study evaluated the functional role of fibrosis diabetic mice. Streptozotocin (STZ) was used to establish a type 1 mouse model. After 10 weeks STZ injection, mice were intravenously injected with Ad‐miR‐222 induce overexpression miR‐222. reduced and improved function Mechanistically, inhibited endothelium mesenchymal transition (EndMT) hearts. Mouse heart...
NAFLD is considered as the hepatic manifestation of metabolic syndrome, which includes insulin resistance, obesity and hyperlipidemia. NASH a progressive stage with severe steatosis, hepatocyte death, inflammation, fibrosis. Currently, no pharmacological interventions specifically tailored for are approved. Ovarian tumor domain, ubiquitin aldehyde binding 1 (OTUB1), founding member deubiquitinases, regulates many metabolism-associated signaling pathways. However, role OTUB1 in unclarified.
Abstract Objective We assessed the predictive capacity of computed tomography (CT)-enhanced radiomics models in determining microvascular invasion (MVI) for isolated hepatocellular carcinoma (HCC) ≤ 5 cm within peritumoral margins and 10 mm. Methods Radiomics software was used feature extraction. least absolute shrinkage selection operator (LASSO) algorithm to establish an effective model predict patients’ preoperative MVI status. Results The area under curve (AUC) values validation sets 5-...
Abstract Mammalian target of rapamycin complex 1 (mTORC1) is evolutionally conserved and frequently activated in various tumors, including colorectal cancer (CRC). It has been reported that the ribosome assembly factor Urb1 acts downstream mTORC1/raptor signaling contributes to digestive organ development zebrafish. Previously, we highlighted URB1 was overexpressed CRC. Here, assessed mTORC1/regulatory associated protein with mTOR (RAPTOR)‐URB1 axis CRC tumorigenesis. We found RAPTOR tissues...
Aim. The robotic technique has been established as an alternative approach to laparoscopy in colorectal surgery. aim of this study was compare short-term outcomes robot-assisted and laparoscopic surgery cancer. Methods. cases or resection were collected retrospectively between July 2015 October 2017. We evaluated patient demographics, perioperative characteristics, pathologic examination. A multivariable linear regression model used assess Short-term included time passage flatus...
Introduction Lateral lymph node (LLN) metastasis in rectal cancer significantly affects patient treatment and prognosis. This study aimed to comprehensively compare the performance of various predictive models predicting LLN metastasis. Methods In this retrospective study, data from 152 patients who underwent lateral dissection were collected. The cohort was divided into a training set (n=86) Tianjin Union Medical Center (TUMC), two testing cohorts: (TUMC) (n=37) Gansu Provincial Hospital...