A5002968243- Pancreatitis Pathology and Treatment
- Biological and pharmacological studies of plants
- Pancreatic and Hepatic Oncology Research
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and disorders
- Genetic and rare skin diseases.
- Retinal Diseases and Treatments
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Immunotherapy and Immune Responses
- Renal function and acid-base balance
- Advanced X-ray and CT Imaging
- Cancer and Skin Lesions
- Pelvic floor disorders treatments
- Inflammasome and immune disorders
- Bone health and treatments
- Neonatal and Maternal Infections
- Bone Metabolism and Diseases
- Tumors and Oncological Cases
- Pneumocystis jirovecii pneumonia detection and treatment
- Phytochemistry and Bioactive Compounds
- Bone and Joint Diseases
- Biosensors and Analytical Detection
- Cardiac Imaging and Diagnostics
- Neuroendocrine Tumor Research Advances
Shanghai Ninth People's Hospital
2024-2025
Shanghai Jiao Tong University
2024-2025
Shanghai Changzheng Hospital
2024
Yunnan University of Traditional Chinese Medicine
2024
Shanghai Tenth People's Hospital
2020-2024
Tongji University
2020-2024
Anhui University of Traditional Chinese Medicine
2020-2024
Jianghan University
2024
First Affiliated Hospital of Xinjiang Medical University
2022
Xinjiang Medical University
2022
Free fatty acid derived from hyperlipidemia contributes to the development of inflammation in pancreas. Here we explore molecular mechanisms acid-induced pancreatitis through cellular experiments and construction a mouse model hyperlipidemic pancreatitis. We found that palmitic stimulation leads M1 polarization macrophage, which secretes cathepsin S via exosomes pancreatic acinar cells activation caspase1-mediated classical pyrolysis pathway, resulting tissue damage. In vivo have also...
Abstract Purpose To examine the association between tear glucose (TG) and presence severity of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods A cross-sectional study. TG was examined by rapid qualitative test strip 160 patients. The DR graded as mild severe DR. were compared positive negative TG. estimated multivariable regression analysis spearman’s rank correlation test, respectively. performance to detect evaluated receiver operating characteristic...
Postpartum hemorrhage can lead to a variety of maternal complications. Tao Hong Si Wu Decoction (THSWD) is traditional Chinese medicine used for treating gynecological diseases. However, the active ingredients THSWD and its pharmacological mechanism treatment postpartum blood stasis still remained unclear. In this study, 201 components were identified in ethanol extract using ultra‐performance liquid chromatography coupled with quadrupole‐time‐of‐flight mass spectrometry, including 59...
Abstract Hypertriglyceridemia-induced acute pancreatitis (HTGP) is characterized by the and excessive release of FFA produced pancreatic lipases. However, underlying mechanisms this disease remain poorly understood. In study, we describe involvement RNA binding protein hnRNPA2B1 in development HTGP. We used palmitic acid (PA) AR42J cells to create a model HTGP vitro. RT-PCR western blot analyses revealed decrease level but not mRNA expression PA-treated cells. Further that was regulated at...
Abstract Background Facial infiltrating lipomatosis (FIL) is a rare condition characterized by congenital facial enlargement. Beyond its impact on physical appearance, FIL can also impair essential functions such as swallowing, chewing, vision, and breathing, imposing substantial physiological psychological burden. Currently, fewer than 80 cases of have been reported, the characteristics management strategies for remain unclear. Methods We reviewed clinical, surgical, radiological records 39...
Abstract Purpose The aim of this study was to explore the improved image quality portal vein using contrast-enhancement boost (CE-boost) technique for visibility abdominal-enhanced computed tomography (CT) scans in clinical practice. Methods This retrospective included 50 patients Group A who underwent routine CT and B abdominal angiography (CTA) with matched body mass index, age, sex. Images were postprocessed CE-boost further enhanced vein. Both subjective objective assessments different...
Simultaneous detection of C-reactive protein (CRP) and procalcitonin (PCT) at the point care is crucial for management infections in patients with inflammation critical settings. The challenge detecting high concentrations CRP alongside low PCT plasma from inflammatory has limited clinical application multiplexed immunoassays. Herein, we developed a lateral flow immunoassay (LFIA) that employs quantum dot nanobeads (QDNBs) varying sizes colors to enable simultaneous quantification human...
Objective. We retrospectively investigated the effect of admission serum calcium levels on length stay (LOS) in patients hospitalized with acute pancreatitis (AP). Methods. Clinical data for 3156 diagnosed AP were obtained from Multiparametric Intelligent Monitoring Intensive Care III (MIMIC-III) database. Restricted cubic spline curve (RCS) functions dose-response analysis curves and logistic regression used to analyze relationship between LOS. Results. All divided into 2 groups (<8.5...
BACKGROUND Functional constipation can occur in children and adults consists of difficult or infrequent bowel movements, painful defecation, the sensation incomplete movement, it be idiopathic. This study aimed to compare findings from high-resolution anorectal manometry (HRAM) balloon expulsion test (BET) 360 patients with functional 73 healthy volunteers. MATERIAL AND METHODS In total, volunteers underwent HRAM BET our hospital January 2017 December 2023. We collected general data all...