Xiaoyan Guo

ORCID: 0000-0001-6372-950X
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About
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Research Areas
  • Parkinson's Disease Mechanisms and Treatments
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Restless Legs Syndrome Research
  • Neurological disorders and treatments
  • Acute Ischemic Stroke Management
  • Balance, Gait, and Falls Prevention
  • Prenatal Screening and Diagnostics
  • Genetic Neurodegenerative Diseases
  • Botulinum Toxin and Related Neurological Disorders
  • Alcohol Consumption and Health Effects
  • Neurological diseases and metabolism
  • Structural Engineering and Vibration Analysis
  • Pregnancy and preeclampsia studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Nutrition and Health in Aging
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cerebrovascular and Carotid Artery Diseases
  • Inflammatory Biomarkers in Disease Prognosis
  • Iron Metabolism and Disorders
  • Nutritional Studies and Diet
  • Chronic Myeloid Leukemia Treatments
  • Birth, Development, and Health

Jiaxing University
2025

Nanjing University of Chinese Medicine
2025

Lishui Central Hospital
2025

Wenzhou Medical University
2025

Affiliated Hospital of Southwest Medical University
2018-2024

Beijing Friendship Hospital
2024

Capital Medical University
2010-2024

Second Affiliated Hospital of Xi'an Jiaotong University
2007-2024

Beijing Institute of Petrochemical Technology
2024

Anhui Agricultural University
2024

Hypertension is a significant global public health challenge. Low-grade inflammation known to facilitate the development of essential hypertension and target-organ hypertensive damage. Neutrophil lymphocyte ratio (NLR) simple reliable indicator that may also be useful in prediction hypertension.Participants were recruited from Tianjin Medical University's General Hospital-Health Management Centre. A total 28,850 initially hypertension-free subjects followed 2007 2013. Adjusted Cox...

10.1093/ajh/hpv034 article EN American Journal of Hypertension 2015-03-30

Prokineticin-2 is confirmed to be involved in the inflammatory process. Inflammation plays an important role pathogenesis of metabolic syndrome (MS). However, whether prokineticin-2 associated with MS or not remains unknown. Thus, we present this study explore association between and a Chinese population. This included 162 middle-aged elderly patients cardiovascular risk factors. The relationship serum levels various cardiometabolic factors, were evaluated. participants >6.32 ng/ml had...

10.1186/s12944-015-0172-5 article EN cc-by Lipids in Health and Disease 2016-01-05

Mitochondrial dysfunction in tissue-specific mesenchymal stem cells (MSCs) plays a critical role cell fate and the morbidity of chronic inflammation-associated bone diseases, such as periodontitis osteoarthritis. However, there is still no effective method to cure diseases by physiologically restoring function mitochondria MSCs. Herein, it first found that inflammation leads excess Ca

10.1002/advs.202103839 article EN Advanced Science 2021-12-11

Affective disorders, especially depressive symptoms, bring such a burden to mortality and morbidity that they are associated with physical psychological health quality of life. Nuts, foodstuff rich in multiple micronutrients, macronutrients, other useful components, were considered be protector against symptoms. Here, we conducted an analysis examine the relationship between nut consumption symptoms.The study performed cross-sectional whether is related symptoms among 13,626 inhabitants...

10.1002/da.22516 article EN Depression and Anxiety 2016-04-20

Aim It is widely known that inflammation related to type 2 diabetes (T2D), but few studies have shown a direct relationship between the immune system and T2D using reliable biomarker. Neutrophil:lymphocyte ratio (NLR) an easy-to-analyze biomarker, assessed NLR T2D. In order evaluate how T2D, we designed large-scale cross-sectional prospective cohort study in adult population. Subjects methods Participants were recruited from Tianjin Medical University General Hospital-Health Management...

10.1530/eje-15-0176 article EN European Journal of Endocrinology 2015-05-08

Objectives To explore the differences in features and impact on quality of life (QOL) non-motor symptoms (NMS) tremor dominant (TD) postural instability gait disorder (PIGD) phenotypes early Parkinson's disease (PD), as well determinants poor QOL for TD PIGD phenotypes. Methods This cross-sectional study recruited 301 patients with PD 101 healthy controls. Specific assessments used NMS included scale (NMSS), Hamilton Rating Scale Depression (HRSD-24), Anxiety (HAMA), Mini-Mental state...

10.1111/ane.12461 article EN Acta Neurologica Scandinavica 2015-07-20

Background: The association between the fasting levels of serum lipids and Parkinson's disease (PD) in Chinese populations remains largely unknown. Methods: This study enrolled 555 sporadic PD patients age-, gender- body mass index (BMI)-matched controls. lipid concentrations all subjects, including total cholesterol, low-density lipoprotein (LDL-C), high-density (HDL-C) triglycerides (TG), were measured. Results: Total LDL-C, HDL-C TG significantly lower than prevalence is subjects with...

10.3109/00207454.2014.979288 article EN International Journal of Neuroscience 2014-10-23

Abstract Enhanced muscle strength is often related to improved insulin sensitivity and secretion, control of lipid metabolism, increased secretion myokines. These factors have emerged as important mechanisms involved in the development progression nonalcoholic fatty liver disease (NAFLD), implying that may be a useful predictor for NAFLD. We aimed assess relationship between grip (GS) NAFLD large-scale adult population. GS was assessed using an electronic hand-grip dynamometer, diagnosed by...

10.1038/srep33255 article EN cc-by Scientific Reports 2016-09-12

Activation of the innate immune system plays a key role in development fatty liver disease (FLD). The complement is major humoral component response and C3 central role, implying that may be powerful predictor or therapeutic target for FLD. However, few studies have assessed association between FLD large population. Here we use cross-sectional study to investigate link serum levels Participants were recruited from Tianjin Medical University's General Hospital-Health Management Centre. Serum...

10.1371/journal.pone.0122026 article EN cc-by PLoS ONE 2015-04-09

BACKGROUND Stroke is a leading cause of mortality worldwide and often results in complex sequelae. Peripheral circulation disorders paralyzed limbs are particularly challenging, presenting as persistent cold sensations cold-induced pain that severely impair patients' quality life. This report presents an innovative approach to managing refractory post-stroke limb coldness using computed tomography (CT)-guided sympathetic nerve radiofrequency ablation. CASE REPORT We present the case...

10.12659/ajcr.946352 article EN cc-by-nc-nd American Journal of Case Reports 2025-01-05

Due to the high volatility of financial markets and prevalence fraud, real-time stock market forecasting for listed companies remains a challenging task. To address these challenges, this study proposes TCNAttention-RAG, hybrid deep learning framework integrating Temporal Convolutional Network (TCN), Multi-Layer Perceptron (MLP), Attention Mechanism, Retrieval-Augmented Generation (RAG) enhanced price forecasting. The model leverages TCN temporal feature extraction, MLP nonlinear...

10.20944/preprints202504.1921.v1 preprint EN 2025-04-23
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