A5044346824- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Dental Health and Care Utilization
- Diet, Metabolism, and Disease
- Oral microbiology and periodontitis research
- Hepatitis B Virus Studies
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 Clinical Research Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Esophageal and GI Pathology
- Hepatitis C virus research
- Oral Health Pathology and Treatment
- Birth, Development, and Health
- Gastroesophageal reflux and treatments
- COVID-19 diagnosis using AI
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Inflammatory mediators and NSAID effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Inflammatory Biomarkers in Disease Prognosis
- HIV/AIDS oral health manifestations
Shanghai Jiao Tong University
2012-2025
Shanghai Children's Hospital
2018-2025
Sichuan University
2021-2025
Third People's Hospital of Huzhou
2025
Huzhou University
2025
Zhongnan Hospital of Wuhan University
2025
Wuhan University
2025
Taiyuan University of Science and Technology
2024
Ningbo University
2024
Zhejiang University
2022-2024
To evaluate periodontal conditions in adults mainland China based on data from the 4th National Oral Health Survey.Data of adult subjects (35- to 44-year-old group [N = 4409], 55- 64-year-old 4622], and 65- 74-year-old 4428]) were analysed. Demographic, socio-economic, personal habit, dental history, health attitude obtained using a questionnaire. Periodontal condition was assessed standardized case definitions 2018 classification scheme. A multivariate analysis performed investigate...
What is the current burden of polycystic ovary syndrome (PCOS) at global, regional, and country-specific levels in 194 countries territories according to age socio-demographic index (SDI)?Slight increases age-standardized incidence PCOS associated disability-adjusted life-years (DALYs) were evidenced among women reproductive (15-49 years) from 2007 2017 global level, most regions countries.No detailed quantitative estimates DALYs by SDI these have been published previously.An age-...
Natural killer (NK) cells have a vital role in killing hepatocellular carcinoma (HCC) cells; however, the mechanism underlying tumor-infiltrating NK (TINK)-cell dysfunction remains poorly understood. Using flow cytometry staining, we precisely characterized frequency, phenotype and function of subsets distinguished by CD27 CD11b 30 patients with HCC comparison to healthy controls. Interestingly, found substantial proportion liver-infiltrating CD11b−CD27− (DN) tumor tissue from patients....
Abstract Chemoresistance to cisplatin is a principal cause of treatment failure and mortality advanced bladder cancer (BC). The underlying mechanisms remain unclear, which hinders the development preventive strategies. Recent data indicate that pyruvate kinase M2 (PKM2), glycolytic enzyme for Warburg effect, strongly upregulated in BC. This study explores role PKM2 chemoresistance whether inhibiting augments chemosensitivity reduces BC growth progression. We found Shikonin binds inhibits...
Berberine (BBR) has been explored as a potential anti-liver fibrosis agent, but the underlying mechanisms are unknown. In current study, we aimed to investigate molecular effect of BBR against liver fibrogenesis in thioacetamide (TAA) and carbon tetrachloride (CCl4) induced mouse fibrosis. addition i.p. injection with TAA or CCl4, mice treatment group received intragastrically. Concurrently, combined treatment, inhibitor were injected ferrostatin-1 (Fer-1). Hepatic stellate cells (HSCs) also...
This study aimed to explore the demographic and distributive features of acute hemorrhagic conjunctivitis (AHC). We constructed seasonal autoregressive integrated moving average (SARIMA) exponential smoothing (ETS) models predict its trend in incidence mainland China provided evidence for government formulate policies regarding AHC prevention.Data distribution characteristics from 2011-2016 were retrieved Public Health Scientific Data website. Monthly data January 2011 June 2019 used...
Liver fibrosis is a chronic disease characterized by different etiological agents; dysregulated interactions between hepatocytes and HSCs contribute to this disease. β-arrestin 1 (ARRB1) plays an important role in liver fibrosis; however, the effect of ARRB1 on crosstalk unknown. The aim study investigate how modulates hepatocyte HSC activation during fibrosis.Normal fibrotic human serum samples were obtained. CCl 4 -induced methionine-choline deficiency-induced NASH models constructed....
AIM:To investigate the etiology and complications of liver cirrhosis (LC) in Southern China. METHODS:In this retrospective, cross-sectional study, we identified cases admitted between January 2001 to December 2010 reviewed medical records.Patient demographics, etiologies were collected, etiological changes illustrated by consecutive years within two time periods (2001-2005 2006-2010).All results expressed as mean ± SD or a percentage.The χ 2 test Student's t -test was used analyze...
Objective To assess the current periodontal status of 35 to 44-year-olds from Chinese population and analyse potential influence factors on disease. Methods The data subjects were collected both urban rural areas all 31 provinces, autonomous regions municipalities mainland China, as part 4th National Oral Health Survey. All aged 44 years old. In total, 4,410 enrolled in present study. Each subject was asked undergo a professional oral examination fill questionnaire. Periodontal health...
Objective This study analyzed the status and factors associated with having a steady homosexual partner (HP) among men who have sex (MSM) to provide scientific basis for developing prevention control strategies acquired immunodeficiency syndrome in this population. Methods A questionnaire survey was conducted participants were MSM recruited online by non-governmental organization May 2024. The divided into two groups based on whether they had HP. Univariate multivariate logistic regression...
Background: Sepsis, as a clinically critical disease, usually induces coagulation disorders. It has been reported that ERBB2 Interacting Protein (Erbin) is involved in the development of various inflammatory diseases, and macrophages are regulation disorders sepsis. However, role Erbin sepsis relationship between macrophage function still unclear. Methods: At cellular level, were treated with lipopolysaccharide (LPS) or MEK inhibitor (PD98059), protein expression levels detected by Western...
To investigate the prognostic value of hematological indices derived from routine blood tests in assessing 30-day mortality risk among elderly patients with bacterial pneumonia at time admission. This study was conducted Second Affiliated Hospital Kunming Medical University. A total 292 were enrolled. diagnosed classified into two groups: survival group (n= 256) and (n=36). Following a Propensity Score Matching 1:1 ratio, differences clinical data between groups analyzed using chi-square...
Importance Head and neck lymphatic malformations (HNLMs) demonstrate considerable variability in their natural history. While some cause chronic severe functional impairment, others are asymptomatic spontaneously regress. Understanding the frequency features associated with regression will aid clinicians families making informed treatment choices avoid unnecessary risks of intervention for a subset patients. Objective To assess incidence, timing, factors spontaneous HNLMs. Design, Setting,...
Biostimulants can improve mineral nutrient effectiveness, but the physiological mechanisms by which seaweed extract, a natural biostimulant, and boron (B) fertilizer promote growth of sugar beet under B deficiency are not clear. In this study, extract were applied B-deficiency (0.32 mg kg-1 soil) potentially B-deficient conditions (0.69 soil), photochemical properties seedlings investigated. The results indicated that application alone or with promoted growth, combined having significantly...
Activation of the innate immune system plays a key role in development fatty liver disease (FLD). The complement is major humoral component response and C3 central role, implying that may be powerful predictor or therapeutic target for FLD. However, few studies have assessed association between FLD large population. Here we use cross-sectional study to investigate link serum levels Participants were recruited from Tianjin Medical University's General Hospital-Health Management Centre. Serum...
Background: Photodynamic therapy (PDT) has demonstrated promising results in the treatment of oral leukoplakia. This study evaluated clinical efficacy and side effects photodynamic Chinese patients with Methods: Twenty-nine leukoplakia were enrolled this study, including both homogenous non-homogenous lesions various dysplastic tissues. All received PDT using a 632 nm laser at 500 mW/cm2 power density dosage 90-180 J/cm2 aminolevulinic acid (ALA) used as photosensitizer. A fixing restricting...
Abstract A family of hybrid complexes combining two biologically active motifs, an artemisinin derivative and a cationic bis(NHC)‐gold(I) unit, has been synthesized. One these complexes, 2 , analyzed by single‐crystal X‐ray diffraction. shows strong anticancer activities on large panel human cancer cell models (prostate, breast, lung, liver, bladder, bone, acute chronic myeloid leukemias) with GI 50 values in the n m range, together high selectivity. An original distinctive mechanism action,...
Developing efficacious drug delivery systems for targeted cancer chemotherapy remains a major challenge. Here we demonstrated kind of pH-responsive PEGylated doxorubicin (DOX) prodrug via the effective esterification and Schiff base reactions, which could self-assemble into biodegradable micelles in aqueous solutions. Owing to low pH values inside tumor cells, these PEG-Schiff-DOX nanoparticles exhibited high loading ability release behavior within cells or tissues upon changes physical...
Rhizosphere environments play a vital role in the nutrient cycling of crops and soil organic nitrogen mineralization. Sugar beet is highly (N)-demanding crop, it necessary to explore relationship between sugar root exudates, microbial community, utilization. In this study, special separation method was employed create rhizosphere (H3) non-rhizosphere (H2 H1) for beet. After 50 d cultivation nearly inorganic-free soil, diversity its correlation with metabolites N were examined. The results...
Few studies have assessed the relationship between a subnormal inflammatory status and metabolic syndrome (MS). We therefore designed cross-sectional 5-year cohort study to evaluate how peripheral blood leukocyte count is related MS. Participants were recruited from Tianjin Medical University General Hospital-Health Management Centre. Both baseline (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn...