Gang Wu

ORCID: 0000-0002-5699-8370
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Heavy Metal Exposure and Toxicity
  • Trace Elements in Health
  • Heavy metals in environment
  • Optical Coatings and Gratings
  • Mercury impact and mitigation studies
  • Iron Metabolism and Disorders
  • Graphene and Nanomaterials Applications
  • Parathyroid Disorders and Treatments
  • Water Quality and Pollution Assessment
  • Advanced Nanomaterials in Catalysis
  • Selenium in Biological Systems
  • Iron oxide chemistry and applications
  • Pharmacy and Medical Practices
  • ATP Synthase and ATPases Research
  • Anesthesia and Neurotoxicity Research
  • Reproductive Biology and Fertility
  • Medicinal Plant Pharmacodynamics Research
  • Calcium Carbonate Crystallization and Inhibition
  • Plant-derived Lignans Synthesis and Bioactivity
  • Advanced Optical Imaging Technologies
  • Photonic and Optical Devices
  • Cell Adhesion Molecules Research
  • Environmental Quality and Pollution
  • Receptor Mechanisms and Signaling

Baotou Medical College
2008-2025

Army Medical University
2025

Inner Mongolia University of Science and Technology
2012-2021

Institute of High Energy Physics
2020

Chinese Academy of Sciences
2020

Mongolian University of Science and Technology
2019

Affiliated Hospital of Guilin Medical College
2010

University of Science and Technology of China
2005-2006

Since silver-nanoparticles (NPs) possess an antibacterial activity, they were commonly used in medical products and devices, food storage materials, cosmetics, various health care products, industrial products. Various silver-NP based devices are available for clinical uses, such as dressing hydrogel (silver-NP-hydrogel) applications. Although the previous data have suggested silver-NPs induced toxicity vivo vitro, there is lack information about mechanisms of biological response potential...

10.1186/1477-3155-10-16 article EN cc-by Journal of Nanobiotechnology 2012-01-01

Increased use of silver nanoparticles (AgNPs) has raised concerns that AgNPs may induce toxic effects. In vitro studies cell monolayers and in vivo have produced conflicting results. The inconsistency these results been mainly due to limitations two-dimensional (2D) monolayer systems.A three-dimensional (3D) epidermal model called EpiKutis®, which exhibits good tissue viability barrier function was developed. cytotoxicity against EpiKutis compared 2D keratinocytes at equivalent doses (0.035,...

10.2147/ijn.s225451 article EN cc-by-nc International Journal of Nanomedicine 2019-12-01

The purpose of this study is to evaluate the overall toxicity nasal instilled nanoscale copper particles (23.5 nm) in mice. Pathological examination, target organs identification, and blood biochemical assay experimental mice were carried out comparison with micro-sized (17 microm). However, only high-dose group nanoparticles (40 mg/kg body weight for three times one week), retarded significant pathological changes observed. There hydropic degeneration around central vein spotty necrosis...

10.1166/jnn.2009.1320 article EN Journal of Nanoscience and Nanotechnology 2009-08-29

We aim to investigate the biological effects of copper particles on murine brain and their underlying mechanism after nasal instillation particles. choose different sizes concentrations nanoparticles for mice intranasal use. Within one week, were sacrificed. Pathological lesions glial cells detected by immunohistochemical assay. Immunohistochemical assay reveals that fibrillary acidic protein (GFAP) increased significantly in all experimental groups, especially nanocopper groups. The...

10.1166/jnn.2014.8290 article EN Journal of Nanoscience and Nanotechnology 2014-02-15

Introduction: Rare-earth nanoparticles in the environment and human body pose a potential threat to health. Although toxic effects of rare-earth have been extensively studied, on early development are not well understood. In this study, we attempted explain neodymium oxide (Nd 2 O 3 ) development. Methods: We added Nd at different concentrations recorded mortality malformation rate per 24 hrs under microscope. The live embryos treated with were imaged as movies Z step lapses confocal...

10.2147/ijn.s220785 article EN cc-by-nc International Journal of Nanomedicine 2020-01-01

After exposing rat embryonic cells to 20 μg/mL of silver nanoparticle (NP) suspension and their released ions for different time periods, nanoparticles were found in cellular nuclei, mitochondria, cytoplasm lysosomes by transmission electron microscopy (TEM). We also observed mitochondrial destruction, distension endoplasmic reticulum apoptotic bodies. Global gene expression analysis showed a total 279 genes that up-regulated 389 down-regulated the silver-NP exposure group, while 3 41 ion...

10.3109/17435390.2014.948942 article EN Nanotoxicology 2014-08-14

The Se content in Se-containing proteins of Se-enriched yeast was successfully identified and quantified by 2-DE combined with SRXRF techniques high resolution sensitivity.

10.1039/c5ja00043b article EN Journal of Analytical Atomic Spectrometry 2015-01-01

Interest in multimodal function optimization is expanding rapidly since real-world problems often require location of multiple optima searching space. The concept restricted evolution introduced to provide optima. Combined with a simple strategy, method can solutions low time consumption. Consequent local search based on the found improves accuracy optimization. proposed applied practical design varied-line-spacing holographic gratings. Optimization results show efficiency and usefulness this method.

10.1109/cec.2005.1554763 article EN 2005-12-13

Mercury (Hg)-, selenium (Se)-, and arsenic (As)- containing proteins in liver tissues of bighead carp grass sampled from a mercury-polluted area Wanshan, Guizhou Province, China, were separated by thin-layer isoelectric focusing. The relative content Hg, Se, As protein bands was measured with synchrotron radiation x-ray fluorescence. results indicated that there at least 3 Hg-containing pI 3.7, 4.8, 6.2 1 band carp. Se found the 3.7 may be corresponding to antagonistic effect against...

10.1080/15287390802216041 article EN Journal of Toxicology and Environmental Health 2008-07-24

Cerium (Ce)-containing compounds are now widely applied in medicine, agriculture, and animal breeding. However, the effects of Ce on humans, especially central nervous system (CNS), remain to be determined. In order investigate whether exposure affected CNS, aim this study was expose female ICR mice varying nanoparticle sizes 35 nm 300 nm, a mixture 1–5 µM cerium dioxide (CeO2) particles through intranasal (i.n.) instillation at daily dose 40 mg/kg body weight. Immunohistochemical data...

10.1080/15287394.2016.1193116 article EN Journal of Toxicology and Environmental Health 2016-09-06

Uniform line spacing plane gratings are introduced into a recording system to generate aspherical wavefronts for varied holographic gratings. Analytical expressions of groove parameters derived the fourth order. A ray-tracing validation algorithm is provided based on Fermat's principle and local search method. The optimized record grating with aid analytical expressions. design example demonstrates exactness superiority optics auxiliary

10.1364/ao.45.005059 article EN Applied Optics 2006-07-06

For a precipitation reaction involving an amorphous phase, the equilibrium equation takes general form (middle), which converts to conventional “reaction quotient” (left) and “solubility product” (right) in two limit cases, respectively.

10.1039/c9cp04250d article EN Physical Chemistry Chemical Physics 2019-01-01

Cerium oxide (CeO2), one of many engineered nanomaterials (ENMs), is composed primarily metal oxides, such as cerium (CeO2). CeO2-containing materials are widely used a polishing agent for glass mirrors, plate glass, television tubes, ophthalmic lenses, and precision optics. The widespread use this nanomaterial (NM) resulted in increased environmental contamination levels consequent human exposure. However, the influence Ce on humans remains to be determined. aim study was expose female ICR...

10.1080/15287394.2019.1686867 article EN Journal of Toxicology and Environmental Health 2019-10-18

Using a free-electron laser source,we have studied the nonlinear absorption in I nSb,Hg1-xCdxTe and InAs semiconductors.By measuring tr ansmission,two -photon-absorption(TPA)has been investigated as function of input power.In two cases,a distinct saturation TPA coefficients has observed.Using an extension these methods,we demonstrated that reduced transmission at high intensities is primarily due to free-carrier-absorption(FCA) electrons nd holes generated by TPA,not directly...

10.7498/aps.52.1403 article EN cc-by Acta Physica Sinica 2003-01-01

Abstract A growing number of individuals are now exposed to neodymium (Nd) owing its extensive applications. However, the biological effects Nd on humans, especially learning and memory, remain elusive. To investigate whether exposure affects in this study female ICR mice were nano 2 O 3 via intranasal instillation at doses 50, 100, 150 mg/kg body weight, daily for 45 days. According Morris water maze data, memory parameters significantly reduced nano‐Nd group than sham control. Furthermore,...

10.1002/tox.23148 article EN Environmental Toxicology 2021-05-02
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