A5065877899- Pelvic floor disorders treatments
- Adolescent and Pediatric Healthcare
- Anorectal Disease Treatments and Outcomes
- Inflammatory Bowel Disease
- Endometriosis Research and Treatment
- Microscopic Colitis
- Colorectal Cancer Surgical Treatments
- Stoma care and complications
- Sexual function and dysfunction studies
- Childhood Cancer Survivors' Quality of Life
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Social Media in Health Education
- Esophageal Cancer Research and Treatment
- Congenital gastrointestinal and neural anomalies
- Hernia repair and management
- Cancer Immunotherapy and Biomarkers
- Sex and Gender in Healthcare
- Immune cells in cancer
- Reproductive System and Pregnancy
- Orthopedic Surgery and Rehabilitation
- Patient-Provider Communication in Healthcare
- Diversity and Career in Medicine
- Maternal and Perinatal Health Interventions
- Colorectal and Anal Carcinomas
University of Oxford
2014-2025
King's College London
2019-2023
University College London
2022
Nightingale Hospital
2021
Florence Nightingale Foundation
2019
Oxford Brookes University
2018
Oxford University Hospitals NHS Trust
2014
Churchill Hospital
2013-2014
University of Pretoria
1998
Onderstepoort Veterinary Academic Hospital
1998
Magnetic resonance enterography (MRE) and ultrasound are used to image Crohn's disease, but their comparative accuracy for assessing disease extent activity is not known with certainty. Therefore, we did a multicentre trial address this issue.
Elbow dysplasia is a non-specific term denoting abnormal development of the elbow. encompasses clinical and radiographic manifestation ununited anconeal process, fragmented medical coronoid osteochondritis dissecans, erosive cartilage lesions elbow incongruity. The net result arthrosis, which may be clinically inapparent or in marked lameness. These conditions diagnosed by means routine special views other imaging modalities, precise cause arthrosis lameness remain undetermined. Breeds most...
The success of checkpoint inhibitors (CPIs) for cancer has been tempered by immune-related adverse effects including colitis. CPI-induced colitis is hallmarked expansion resident mucosal IFNγ cytotoxic CD8+ T cells, but how these arise unclear. Here, we track CPI-bound cells in intestinal tissue using multimodal single-cell and subcellular spatial transcriptomics (ST). Target occupancy was increased inflamed tissue, with drug-bound located distinct microdomains distinguished specific...
In Brief BACKGROUND: The role of internal rectal prolapse in the origin fecal incontinence remains to be defined. our institution, laparoscopic ventral rectopexy is offered patients with high-grade and incontinence. OBJECTIVE: present study was designed evaluate functional outcome after associated prolapse. DESIGN: This as a prospective observational study. SETTINGS: took place university hospital. PATIENTS: Between 2009 2011, 72 not responding maximum medical treatment (including...
Abstract Background Inflammatory bowel disease (IBD) is often diagnosed in early adulthood and affects individuals’ sex life. People living with IBD report sexual dysfunction reduced satisfaction. While previous studies have demonstrated patients’ need for information about health from healthcare providers, nurses’ practices well-being (SWB) remain unclear. This study aimed to identify international SWB support patients IBD. Methods an qualitative study. Nurses substantial experience nursing...
Abstract Background Previous studies have highlighted that individuals with inflammatory bowel disease (IBD) often experience concerns related to sexual well-being (SWB). For those IBD who undergone stoma formation, there is an overall improvement in quality of life, but the initial period marked by significant distress, largely due a lack information. What remains unclear specific SWB faced living both and permanent stoma, as well level support they receive addressing concerns.This study...
Abstract Background Addressing sexual wellbeing (SWB) in inflammatory bowel disease (IBD) clinical practice remains a challenge for both patients and nurses. While existing evidence highlights patients' need these discussions, little is known about the barriers to such conversations from patients’ nurses’ perspectives. Evidence of healthcare professionals' perspectives on addressing SWB oncology, dermatology cardiovascular nursing perspective, but not IBD specialist perspective. This study...
Abstract Background Surgery for inflammatory bowel disease (IBD) often carries a hidden cost in terms of sexual function. Traditionally, when measuring outcomes, the focus has been on those easily measured, quantified, analysed and applied to health economics, such as mortality, morbidity recurrence. Whilst research this subject area is expanding, there are limited qualitative data specifically investigating patient experiences dysfunction post-surgery IBD. This study aims produce an...
Inflammatory bowel disease [IBD] affects all aspects of life, yet little is known about the impact condition on intimacy and sexuality if such concerns should be discussed with health care professionals. This hermeneutical phenomenological study aimed to explore experiences people living inflammatory discussing their professionals.Participants [n = 43] aged 17-64 years were recruited. Data collected via in depth interviews anonymous narrative accounts [Google Forms]. Thematic analysis was...
Abstract Aim Pelvic floor retraining is considered first‐line treatment for patients with faecal incontinence or obstructed defaecation. There are at present no data on the effect of a high grade internal rectal prolapse outcomes pelvic retraining. The current study aimed to assess this influence. Method In all, 120 consecutive were offered predominant symptom was in 56 (47%) and defaecation 64 (53%). Patients assessed before after therapy using Fecal Incontinence Severity Index ( FISI ), P...
The simplified magnetic resonance enterography [MRE] index of activity [sMARIA], London, and 'extended' scoring systems are widely used in Crohn's disease [CD] to assess activity, although validation studies have usually been single-centre, retrospective, and/or few readers. Here, we evaluated these MRE indices within a prospective, multicentre, multireader, diagnostic accuracy trial.A subset participants [newly diagnosed or suspected relapse] recruited the METRIC trial with available...
Abstract Background Sexual well-being is a state of sexual happiness and satisfaction that combines mental stability physical health as well builds on mutual caring intimacy with the partner. Patients inflammatory bowel disease (IBD) undergo distress they experience dating, marriage, childbirth while living disease. Previous studies have indicated importance support related to but suggested it difficult topic for discussion. Hence, this study sought clarify nurses' specific difficulties...
Abstract Background Sexual dysfunction after Inflammatory Bowel Disease (IBD), pelvic and perineal surgery is common but poorly discussed, investigated treated in the peri-operative period. There remains no standardised measurement tool to assess sexual function routine use for patients undergoing benign colorectal surgery. The necessity open dialogue regarding was evidenced a patient-led study conducted by Dames et al. Our primary objective undertake systematic review of instruments,...
Abstract Aim To explore patient experiences of intimacy and sexuality in those living with inflammatory bowel disease. Design An interpretative phenomenological study guided by van Manen's framework. Thematic analysis was conducted through interpretation reflection on four existential domains: body, relationships, time space. Methods Data were collected during 2019–2021 from 43 participants via face‐to‐face or telephone interviews, as well anonymous collection narratives submitted Google...
Abstract Background Vulvar Crohn’s disease is a rare cutaneous manifestation of inflammatory bowel and to date, studies have reported on under 300 cases worldwide. The condition has an increased risk malignancy, diagnosis often difficult. Treatment protocols are yet be developed. This paper aimed provide the first account patients’ experience living with vulvar Crohn’s. Methods A previous qualitative study exploring experiences sexual well-being in discussing healthcare professionals found 3...
Abstract Background People with inflammatory bowel disease have a high incidence of stoma formation, either temporary or permanent. Although can be life saver, for some it negatively impact body image and psycho-emotional wellbeing. Sexual function also affected by poor image. Therefore, intimacy sexuality should addressed in clinical settings during care. We aimed to explore the experiences sexual wellbeing concerns people living IBD stoma, how these were healthcare professionals. Methods...
Research with young people is essential for identifying and addressing current future health issues of our youth. Health research adolescents often involves topics considered sensitive can include around body image, healthcare practices, sexuality substance use. Some areas are more than others, Lee Renzetti (1993)argue that the degree sensitivity directly related to perceived level risk participants. Adolescence also a crucial developmental period, in which become increasingly independent...
Traditionally, pelvic floor retraining for faecal incontinence or obstructed defaecation has been delivered to patients through individual sessions with a specialist nurse, resource-intensive practice. This study aimed assess whether similar outcome can be achieved by delivering in small groups, allowing considerable savings the use of resources.Data were collected prospectively database. Patients received either individually group setting and completed baseline follow-up questionnaires. Two...
Abstract Background Inflammatory bowel disease (IBD) causes significant difficulties in peoples’ lives, and negatively affects their sexual wellbeing (SWB). Evidence from diverse population is paramount when we seek equality, diversity inclusion healthcare.1 The evidence on patient SWB experience the context of IBD comes predominantly white participants.2 This study explored experiences people with a ethnic background, cultural religious influences discussing clinical setting. Methods...
The prevalence of faecal incontinence in the general population is estimated to be between 11% and 15%, with a subgroup younger women experiencing higher linked childbirth injury. Such injury occur up 16% vaginal births, equating potentially 80,000 year who experience variety symptoms from perineal pain, urgency, psychological issues. perspectives living as result are largely missing data. This project aimed address this by bringing together women's using thematic synthesis.A database search...