A5070759102- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Corneal Surgery and Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Ocular Infections and Treatments
- Cell Adhesion Molecules Research
- Retinal Development and Disorders
- Ophthalmology and Eye Disorders
- Cerebrovascular and Carotid Artery Diseases
- Ocular Diseases and Behçet’s Syndrome
- Traumatic Ocular and Foreign Body Injuries
- Visual perception and processing mechanisms
- TGF-β signaling in diseases
- Systemic Lupus Erythematosus Research
- Cardiovascular Health and Disease Prevention
- Retinopathy of Prematurity Studies
- Neurological and metabolic disorders
- Management, Economics, and Public Policy
- Neurological Disorders and Treatments
University of Palermo
2013-2022
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2021
University of Catania
2020
Tecnologie Avanzate (Italy)
2005-2018
Clinica Luganese Moncucco
2005-2015
San Salvatore Hospital
1991
To determine the epidemiological characteristics and visual outcome of ocular trauma in southern Italy. All cases admitted to Department Ophthalmology Palermo University, Italy, from January 2001–December 2005 were retrospectively reviewed for open- or closed-globe injury (OGI CGI). Data extracted included age, sex, residence, initial final acuity (VA), cause treatment injury, hospitalization. The injuries classified by Ocular Trauma Classification System (OTCS) Birmingham Eye Terminology...
Abstract Purpose To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep (DVD) their correlation with functional (best‐corrected visual acuity, BCVA) anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RRD) repair. Method Patients RRD eyes, successfully treated a single pars plana vitrectomy (PPV) gas tamponade minimum 12 months follow‐up, were re‐examined. Foveal SVD, DVD FMT evaluated by...
Clinical studies comparing trabeculectomy augmented with Ologen implant (OLO) versus plus mitomycin-C (MMC) show contradictory results. To obtain long-term data, we report an extended 5-year follow-up trial evaluating the safety and efficacy of OLO as adjuvant compared to low-dosage MMC in trabeculectomy. Forty glaucoma patients (40 eyes) assigned or Ologen. Primary outcome: target IOP at ≤21, ≤17 ≤15 mmHg; complete qualified success endpoint rates. Secondary outcomes: visual acuity (VA),...
To compare the efficacy of non-penetrating deep sclerectomy without implant with Crozafon-De Laage punch trabeculectomy, and to evaluate effect simultaneous temporal approach phacoemulsification on both techniques.Department Ophthalmology University Palermo.Prospective randomized clinical trial. Patients intervention procedures: Sixty-five patients (65 eyes) primary open angle glaucoma (POAG) or pseudoexfoliative (PEXG): 32 eyes underwent (NPDS), 17 as single procedure 15 combined...
Our previous studies documented that human fibroblast-limbal stem cells (f-LSCs) possess immunosuppressive capabilities, playing a role in regulating T-cell activity. This study highlights the molecular activities by which f-LSCs can attenuate inflammatory responses of self-reactive peripheral blood mononuclear (PBMCs) collected from patients with autoimmune endocrine diseases (AEDs). Anti-CD3 activated PBMCs twenty healthy donors and fifty-two AEDs were cocultured on f-LSC monolayer....
The study purpose was to assess the efficacy of a preservative-free 0.6% povidone iodine eye drops as perioperative prophylactic treatment for reducing conjunctival bacterial load and rate needle contamination in patients undergoing intravitreal anti-vascular endothelial growth factor injection. Enrolled were randomized either group (0.6% iodine, three day-prophylactic before injection) or control (placebo, treatment). Conjunctival swabs obtained after both groups. Intravitreal injections...
<i>Aims:</i> To compare the long-term effects of low-dosage mitomycin C (MMC) in both deep sclerectomy (DSMMC) and trabeculectomy (TPMMC) on intraocular pressure (IOP). <i>Methods:</i> Analysis extended follow-up data from a prospective clinical trial. Forty patients were originally randomised to undergo either DSMMC (19 eyes) or TPMMC (21 eyes). Follow-up was performed at postoperative day 1, weeks 2 3, as well months 6, 9, 12, 18, 24, 36 48. Two- three-week not...
PURPOSE: To evaluate the effect of α1-adrenergic receptor antagonists (α1-ARAs) on pupil diameter and determine whether predicts intraoperative floppy-iris syndrome (IFIS). SETTING: Ophthalmology Section, Palermo University, Palermo, Italy. DESIGN: Prospective cohort study. METHODS: Male outpatients taking tamsulosin, α1-ARAs, or no α1-ARAs having phacoemulsification were recruited. Pupils measured 1 month preoperatively, immediately postoperatively under mesopic low (0.4 lux) high (4.0...
<h3>Aim</h3> To assess the efficacy and safety of ranibizumab in treatment choroidal neovascularisation (CNV) caused by pathologic myopia (PM). <h3>Design</h3> Prospective, multicentre, interventional case series. <h3>Methods</h3> 40 eyes 39 consecutive patients with PM CNV were treated ‘on demand’ intravitreal injection 0.5 mg. Final best corrected visual acuity (BCVA) its change from baseline main outcome measures. Changes optical coherence tomography (OCT) central retinal thickness (CRT)...
To compare IOP behavior after deep sclerectomy (DS) and trabeculectomy with the Crozafon-De Laage Punch (TP), using low-dosage intraoperative mitomycin C (MMC) in both techniques.The study was a prospective randomized clinical trial. All patients met inclusion exclusion criteria, were scheduled for glaucoma surgery. Forty to undergo either nonpenetrating DS MMC (DSMMC) (19 eyes) or TP (TPMMC) (21 eyes). Postoperative examinations performed at 1st day, 1st, 2nd 3rd weeks 3rd, 6th, 9th 12th...
: To evaluate the presence of type A behavior in patients affected by open-angle glaucoma (OAG) and possible role psychophysiological stress as a risk factor for OAG.Fifty patients, 30 women 20 men, OAG, underwent ophthalmological examination consisting complete biomicroscopy, tonometry daily tonometric curve, visual field means computerized perimeter "Octopus 1-2-3," its assessment with Glaucoma Staging System 2, morphologic monitoring retinal nerve fiber layer GDx VCC psychological...
In Brief Purpose: To compare the efficacy of a mixture silicone oil and perfluorohexyloctane (Densiron 68) with C2F6 gas endotamponade in retreatment persistently open full-thickness macular holes. Methods: this prospective randomized study, 21 consecutive patients who were unsuccessfully operated on for large idiopathic hole randomly assigned to undergo second vitrectomy 20% perfluoroethane (C2F6, Group A) or Densiron 68 tamponade (Group B). Primary outcomes: Endpoint (12 months) closure...
The purpose of this study was to investigate refraction at birth and during the first year life in a large cohort babies born single center Northern Italy. We also aimed analyze refractive errors relation gestational age birth. An observational ophthalmological assessment performed within 24 h on 12,427 newborns. Refraction examined using streak retinoscopy after administration tropicamide (1%). Values range between +0.50 ≤ D +4.00 were defined as physiological Newborns with values outside...
The aim of this research was to study the relevance long-term follow-up electroretinographic oscillatory potentials (OPs) in predicting onset minimal non-proliferative diabetic retinopathy insulin-dependent diabetes patients.A total 80 diabetics, with normal fundi and OPs at first examination, were followed prospectively for 10 years. Oscillatory measured fundus examinations performed once or twice per year.During follow-up, 35% patients developed after a mean disease duration 12 +/- 2 A...
The purpose of this study was to report the visual outcome intravitreal therapy with ranibizumab choroidal neovascularization secondary angioid streaks after 1-year follow-up.Nine patients (age, 58 +/- 4 years; range, 53-65 years) were treated off-label injections 0.3 mg ranibizumab. Primary outcomes best-corrected acuity changes (Early Treatment Diabetic Retinopathy Study logarithm minimum angle resolution and letters) optical coherence tomography macular thickness changes.Mean follow-up 14...
Abstract The choroid is the most vascularized structure of eye and plays a central role in development retinal vascular changes that occur arterial hypertension. Changes choroidal thickness (ChT) assessed by optical coherence tomography (OCT) technology could reflect complications Also, intrarenal hemodynamic damage, associated with endothelial dysfunction, demonstrated to be good indicator systemic morphofunctional impairment. aim this study assess relationship between ChT renal...
Abstract. Purpose: To test the expanded polytetrafluoroethylene (ePTFE) as a new adjuvant in trabeculectomy. Methods: Consecutive glaucoma surgical inpatients were observed at Department of Ophthalmology Palermo University. Sixty patients (60 eyes) randomly assigned to undergo trabeculectomy (T), with mitomycin‐C (TMMC), ePTFE (TG) or and (TGMMC). Postoperative visits scheduled 24 hr, 7 days, 1, 3, 6, 12, 18 months. Complete success qualified assessed two target intraocular pressure (IOP)...