A5052271751- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Corneal surgery and disorders
- Ocular Oncology and Treatments
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Ocular Infections and Treatments
- Vascular Malformations Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Retinal Development and Disorders
- Cerebral Venous Sinus Thrombosis
- Traumatic Ocular and Foreign Body Injuries
- Nanoplatforms for cancer theranostics
- COVID-19 and healthcare impacts
- MicroRNA in disease regulation
- Retinoids in leukemia and cellular processes
- Lysosomal Storage Disorders Research
- Neonatal Health and Biochemistry
- Reservoir Engineering and Simulation Methods
- Dermatologic Treatments and Research
Medical University of Lublin
2018-2025
Federico II University Hospital
2022-2025
University of Naples Federico II
2022-2025
Universitätsklinik für Augenheilkunde
2024
Ophthalmology Clinic
2014-2024
University of Jordan
2024
University Hospital of Zurich
2020-2023
University of Zurich
2020-2023
Public Health Department
2023
Cardinal Stefan Wyszyński University in Warsaw
2020-2022
Uveal melanoma (UM) represents approximately 5–6% of all diagnoses and up to 50% patients succumb their disease. Although several methods are available, accurate diagnosis is not always easily feasible because potential accidents (e.g., intraocular hemorrhage). Based on the assumption that profile circulating miRNAs often altered in human cancers, we verified whether UM showed different vitreous humor (VH) or serum miRNA profiles with respect healthy controls. By using TaqMan Low Density...
The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on practical activities and didactic teaching of residents fellows. This survey aimed to propose long-term changes for ophthalmology training based the experienced by trainees their perception new opportunities.An online was distributed in multiple countries. Descriptive statistics were used analyse data.A total 504 analyzable responses collected from 32 different current COVID-19 described as "severe" most...
The recent outbreak of coronavirus disease 2019 (COVID-19) has been declared a public health emergency worldwide. scientific community put in much effort and published studies that described COVID-19’s biology, transmission, clinical diagnosis, candidate therapeutics, vaccines. However, to date, only few data are available on the impact COVID-19 pandemic ophthalmological care different systems, its future consequences terms disability, access sight-saving cures for many patients. To reduce...
Background Though several procedures of IOL implantation have been described (sutured scleral fixation, intra-scleral angle-supported anterior chamber, and chamber or retropupillary iris-claw IOLs), there are no randomized trials which comparing different techniques. Hence, the surgical treatment aphakia still remains controversial challenging. The purpose this study was to compare long-term efficacy rate complications versus posterior Iris-claw intraocular lenses (IOL) correct for without...
Background and Objectives: Age-related macular degeneration (AMD) remains a leading cause of legal blindness. Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for neovascular AMD (nAMD). The choroid plays key role in is affected by anti-VEGF treatment. Faricimab, bispecific antibody additionally targeting angiopoietin 2 (Ang2), was recently approved nAMD This study investigates effect Faricimab on choroidal flow signal. Materials Methods: Optical coherence...
Abstract Purpose To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep (DVD) their correlation with functional (best‐corrected visual acuity, BCVA) anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RRD) repair. Method Patients RRD eyes, successfully treated a single pars plana vitrectomy (PPV) gas tamponade minimum 12 months follow‐up, were re‐examined. Foveal SVD, DVD FMT evaluated by...
The aim of this study was to compare the therapeutic effect intravitreal treatment with ranibizumab and dexamethasone using specific swept-source optical coherence tomography retinal biomarkers in patients diabetic macular edema (DME).156 treatment-naïve DME were divided two groups: 75 received 3 monthly injections 0.5 mg (Lucentis®) (Group 1) 81 an implant 0.7 (Ozurdex®) 2). Patients evaluated at baseline (V1), three months post-treatment Group 1, 2 (V2). Best-corrected visual acuity (BCVA)...
To assess the impact of Jordanian's Corona Virus Disease (COVID-19) lockdown on visual acuity and macular thickness in patients with edema receiving intravitreal injections, to ethical endeavor among serious sight threatening conditions.This retrospective observational study included planned for injections who did not complete course before (ie, 20th March 2020). Data demographics, indication injection, corrected distance (CDVA), central Optical Coherence Tomography (OCT) after...
Background: During the first COVID-19 pandemic outbreak, a new triage concept had to be implemented for patients with retinal diseases having scheduled appointment at medical retina clinic. In this study, we aimed assess patients’ confidence in and satisfaction regarding received treatment during outbreak. Methods: This retrospective study included all diagnosed disease, triaged into three priority groups based on their condition’s urgency lockdown. After restrictions were eased, subset of...
To investigate the neuroprotective effect of brimonidine after retinal ischemia damage on mouse eye. Glaucoma is an optic neuropathy characterized by ganglion cells (RGCs) death, irreversible peripheral and central visual field loss, high intraocular pressure. Ischemia reperfusion (I/R) injury model was used in C57BL/6J mice to mimic conditions glaucomatous neurodegeneration. Mouse eyes were treated topically with pattern electroretinogram assess function. A wide range inflammatory markers,...
Abstract Purpose To evaluate and compare the visual outcomes of an enhanced monofocal intraocular lens (IOL) with two different IOLs. Setting Eye Clinic, Department Medicine, Surgery Health Sciences, University Trieste, Italy. Design Prospective, single-center, single-masked, randomized controlled clinical study. Methods The study included patients undergoing phacoemulsification IOL implantation. Patients were consecutively by block randomization assigned in a 1:1:1 allocation ratio to three...
Purpose: We aimed to evaluate the feasibility of using a novel device, Smart Eye Camera (SEC), for assessing tear meniscus height (TMH) after fluorescein staining and agreement results with measurements obtained standard slit lamp examination. Methods: TMH was assessed both SEC conventional The images were analyzed software ImageJ 1.53t (National Institutes Health, Bethesda, MD, USA). A common measurement unit scale established based on paper strip, which used as calibration marker convert...
To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up.
Abstract Purpose To assess the incidence of normal vision following anatomically successful macular hole surgery and associated clinical variables. Methods Multicentre, retrospective chart review. Preoperative, intraoperative postoperative data were extracted from electronic medical records seven European vitreoretinal units. Inclusion criteria as follows: eyes undergoing primary vitrectomy for idiopathic full‐thickness January 2015 to 2018; closure confirmed by spectral domain optical...
To investigate subclinical and clinical abnormalities in retinal choroidal vascular plexuses patients with SSc by means of optical coherence tomography angiography (OCT-A).A total 20 consecutive were recruited compared healthy subjects. Quantitative analysis vessel density (VD), choriocapillaris plexus flow index (CCP-FI) vascularity performed on OCT-A images the superficial capillary (SCP), deep (DCP) CCP for all patients. Images further reviewed two independent readers assessment...
This is a retrospective, multicenter study of consecutive patients with nAMD scheduled for visit and/or treatment an intravitreal injection (IVI) during the 3 months before lockdown in Ophthalmology Departments six centers Europe.The was conducted on 546 patients, which 55.13% were females, almost 100% White/Caucasian race, and 71.53% presented type 1 macular neovascularization (NVM). A total 62.82% (343 patients) that clinic visits quarantine did not attend either to or lockdown. The mean...
To compare intravitreal aflibercept alone versus combined with oral anti-inflammatory supplementation in patients diabetic macular edema (DME). A prospective, randomized study included 134 treatment-naive eyes central-involving DME. Participants were assigned to receive either (Group A) or Lenidase® B, containing baicalin, bromelain, and escin). Both groups followed a treat-and-extend (T&E) regimen. The primary outcome was the number of injections over 24 months. Secondary outcomes changes...
Purpose The aim of the present study was to assess expression miRNAs in Vitreous Humor (VH) patients with Macular Hole (MH) and Epiretinal Membrane (ERM) compared a control group. Methods In this prospective, comparative study, 2-ml VH extracted from core vitreous chamber consecutive who underwent standard vitrectomy for ERM MH. RNA TaqMan® Low Density Arrays (TLDAs) were used profile transcriptome 754 miRNAs. Results validated by single assays. Finally, we created biological network...
The study purpose was to assess the efficacy of a preservative-free 0.6% povidone iodine eye drops as perioperative prophylactic treatment for reducing conjunctival bacterial load and rate needle contamination in patients undergoing intravitreal anti-vascular endothelial growth factor injection. Enrolled were randomized either group (0.6% iodine, three day-prophylactic before injection) or control (placebo, treatment). Conjunctival swabs obtained after both groups. Intravitreal injections...