- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Endometrial and Cervical Cancer Treatments
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Ocular Diseases and Behçet’s Syndrome
- Ocular Oncology and Treatments
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Health Research
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Cerebral Venous Sinus Thrombosis
- Inflammatory mediators and NSAID effects
- Ovarian cancer diagnosis and treatment
- Celiac Disease Research and Management
- Colorectal Cancer Treatments and Studies
- Microscopic Colitis
- Ocular Infections and Treatments
- Uterine Myomas and Treatments
University of Catania
2014-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2024
University of Brescia
2014-2023
Creative Commons
2023
Johnson & Johnson (Canada)
2023
Carl Zeiss (Germany)
2023
Oculus Optikgeräte (Germany)
2023
Fondazione G.B. Bietti
2023
Fondazione Roma
2023
Ministero della Salute
2023
Lymphatic dissemination from the primary tumor is a major mechanism by which breast cancer cells access systemic circulation, resulting in distant metastasis and mortality. Numerous studies link activation of hypoxia-inducible factor 1 (HIF-1) with angiogenesis, metastasis, patient However, role HIF-1 lymphatic poorly understood. In this study, we show that promotes direct transactivation gene encoding platelet-derived growth B (PDGF-B), has proliferative chemotactic effects on endothelial...
Purpose . To construct an inexpensive, convenient, and portable attachment for smartphones the acquisition of still live retinal images. Methods A small optical device based on principle direct ophthalmoscopy was designed to be magnetically attached a smartphone. Representative images normal pathological fundi were taken with device. Results field-of-view up ~20° captured at clinical resolution each fundus image. The cross-polarization technique adopted in design dramatically diminished...
Purpose: To evaluate the effect of 24-h peak intraocular pressure (IOP) on progression primary open-angle glaucoma (POAG) and 24 h time points that best predict pressure. Methods: A retrospective analysis clinical data evaluating long-term glaucomatous in patients with POAG who were previously a study authors (IOP readings at 2/6/10 A.M. PM); had ≥3 treated 10 (±1 h) IOP measurements over 5-years after an untreated baseline; curve IOP±2 mmHg within mean 5-years. Results: We included 98...
Purpose of the Study: The purpose study was to determine agreement between smartphone ophthalmoscopy and slit-lamp indirect biomicroscopy when assessing vertical cup-to-disc ratios (VCDRs). Materials Methods: This a clinical-based, prospective, comparative instrument performed in 110 patients with ocular hypertension (OH) or primary open angle glaucoma (POAG). Patients underwent estimation VCDR by undilated 2 masked specialists. Results: differences mean estimations obtained each techniques...
The ocular fundus examination is infrequently and poorly performed in the emergency department (ED) clinical settings, placing patients at risk for missed diagnosis of hypertensive emergencies. aim this study was to investigate feasibility photography with a smartphone small optical device an ED setting compare it traditional examination.The included 52 consecutive (mean age 69 ± 16 years, 50% women) presenting hospital acute increase blood pressure (SBP > 180 and/or DBP 100 mmHg). When...
The study purpose was to assess the efficacy of a preservative-free 0.6% povidone iodine eye drops as perioperative prophylactic treatment for reducing conjunctival bacterial load and rate needle contamination in patients undergoing intravitreal anti-vascular endothelial growth factor injection. Enrolled were randomized either group (0.6% iodine, three day-prophylactic before injection) or control (placebo, treatment). Conjunctival swabs obtained after both groups. Intravitreal injections...
To compare the predicted vault using machine learning with achieved online manufacturer's nomogram in patients undergoing posterior chamber implantation an implantable collamer lens (ICL).Centro Oculistico Bresciano, Brescia, Italy, and I.R.C.C.S.-Bietti Foundation, Rome, Italy.Retrospective multicenter comparison study.561 eyes from 300 consecutive who underwent ICL placement surgery were included this study. All preoperative postoperative measurements obtained by anterior segment optical...
Abstract Adult male Rana esculenta were placed under several combinations of light and temperature in different periods the year to elucidate regulation various testicular phases by environmental factors discover mechanism through which these act upon testis. In nature quiescence spermatogenesis winter is due solely low temperature. Under controlled experimental conditions a 4°C, whatever photoperiod, impairs at any time year. The early spring resurgence new wave depends gradual rise both...
Abstract Purpose To evaluate the inflammation associated with use of standard silicone oil (polydimethylsiloxane; PDMS) and heavy (HSO) Densiron‐68™ in patients undergoing vitrectomy for retinal detachment. Materials Methods A prospective study was performed involving 35 scheduled to undergo Patients received PDMS or HSO according superior inferior localization tears, respectively. For assessing inflammation, prostaglandin E2 (PGE 2 ) interleukin‐1 α (IL‐1 levels were evaluated aqueous....
Background: Despite advances in uveal melanoma (UM) diagnosis and treatment, about 50% of patients develop distant metastases, thereby displaying poor overall survival. Molecular profiling has identified several genetic alterations that can stratify with UM into different risk categories. However, these are currently dispersed over multiple studies methodologies, emphasizing the need for a defined workflow will allow standardized reproducible molecular analyses. Methods: Following findings...