A5067508824- Escherichia coli research studies
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Dermatology and Skin Diseases
- Phenothiazines and Benzothiazines Synthesis and Activities
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Gut microbiota and health
- Anesthesia and Pain Management
- Antimicrobial Resistance in Staphylococcus
- Essential Oils and Antimicrobial Activity
- Urinary Tract Infections Management
- Advancements in Transdermal Drug Delivery
- Bee Products Chemical Analysis
- Vibrio bacteria research studies
- Nephrotoxicity and Medicinal Plants
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- 3D Printing in Biomedical Research
- Plant Pathogens and Fungal Diseases
- Veterinary Pharmacology and Anesthesia
- Phytochemical Studies and Bioactivities
- Antimicrobial Peptides and Activities
- Drug-Induced Hepatotoxicity and Protection
- Bacterial Genetics and Biotechnology
- Cancer, Stress, Anesthesia, and Immune Response
University of Pecs
2014-2025
Continuous development of additive manufacturing technologies has reached new areas, including medical research and healthcare applications, where precision, highly accurate reproducibility, disinfection, or even sterility the end product is essential. The study aims to critically evaluate effect different sterilization disinfection methods for most commonly used materials in device development: PLA (polylactic acid), PETG (polyethylene terephthalate glycol), ABS (acrylonitrile butadiene...
The uropathogenic Escherichia coli strain 536 (O6:K15:H31) carries two unstable DNA regions on its chromosome which were termed pathogenicity islands (Pais). Both islands, Pai I and II, are incorporated into tRNA specific loci: is located in the gene for selenocysteine ( selC ), II integrated leucine‐specific locus leuX . Mutant 536−21 has lost together with intact genes. While a virulent strain, number of properties, including vivo virulence. In previous publications we reported that genes...
Abstract Background Basic science knowledge is essential for understanding clinical studies and enhancing reasoning in medical practice. However, students retain only a portion of the gained during early years school. We aimed to examine students’ retention repeated recently learned topics physiology microbiology with additional analysis individual variability. Given that prior have raised concerns about validity rate as an indicator stable knowledge, we also explored alternative measures...
Asymptomatic bacterial colonization of the urinary bladder (asymptomatic bacteriuria, ABU) can prevent by uropathogens and thus symptomatic tract infection (UTI). Deliberate with E.coli ABU isolate 83972 has been shown to outcompete UTI interference. Many isolates evolved from uropathogenic ancestors and, although attenuated, may still be able express virulence-associated factors. Our aim was screen for efficient safe candidate strains that could used as alternatives preventive therapeutic...
ABSTRACT The association of a hemolytic phenotype with the carriage α-hemolysin gene ( hlyA ) and/or silent hemolysin sheA or clyA among 540 extraintestinal clinical isolates Escherichia coli and 110 fecal from healthy individuals was investigated. Though HlyA is an important virulence factor in E. infection, role SheA not completely clarified. Two + strains that lacked possessed no other genes were identified. No identified, suggesting there possible incompatibility between chromosome .
Post-antibiotic era requires the use of alternative pesticides against bacterial infections. One potential application field is agriculture, where are routinely applied in combinations. In this study we tested interference antibacterial effects two antimicrobials with basically different mode actions if together vitro by using Enterohemorrhagic E. coli strain Sakai as a modelorganism, one pathotype that frequently associated meat and plant derived TiO2 photocatalytically active nanomaterial,...
Drugs used in anesthesia may influence bacterial growth (1). Used ampules and syringes be contaminated a busy environment (2). Epidural space infection association with epidural is rare. The antibacterial effects of local anesthetics themselves contribute to this infrequent incidence. A anesthetic was first reported kill bacteria 1909 (3). Since then activity other has been confirmed (1) but there no study on the effect undiluted ropivacaine at room temperature. We investigated 2 mg/mL 10...
Introduction Infection is a leading cause of perioperative complications, often increasing the time patients need to stay in hospital and sometimes causing death. The suspicion that anaesthesia was factor post-operative infection dates from beginning century [1]. There are early investigations on direct effects anaesthetics bacteria, but more recent concern depressed immunocompetence. Most investigators have studied leucocytes lymphocytes shown immune function, although some studies...
Disturbed epidermal proliferation and keratinization are major features of psoriatic skin lesions. The so-called mouse tail test is known as an animal model to evaluate the antipsoriatic efficacy topical drugs with rgard induction orthokeratosis. purpose present study was investigate effect tazarotene, a novel, receptor-specific retinoid, by in direct comparison dithranol representing classical compound. tails CFLP mice were treated tazarotene gel (0.1%, 0.05%), ointment (1.0%), tretinoin...
Introduction Several Aristolochia species were used as medicinal herb across Europe and in recent years, their antimicrobial activity has also been investigated. Materials methods In this study, A. clematitis was selected to evaluate the aristolochic acids I II (AA AA II) concentrations of methanol, hexane, butanol, ethyl acetate extracts root, stem, leaf, fruit. contents measured by a validated high-performance liquid chromatography–ultraviolet method. Results Each fraction plant contained...
The application of EMLA cream is indicated for topical anesthesia the skin in connection with IV cannulation. Recently, we described that has an antibacterial effect vitro.The impact local anesthetic lidocaine/prilocaine (EMLA) on intact human flora was compared to alcohol-based disinfectant (Skinsept Pur). Samples were taken from 0 12 h after treatment.The number colony forming units (cfu) decreased significantly both and Skinsept Pur treatment 44.9 +/- 1.3 (42.4 7.0) 0.9 0.17 (1.61 0.47)...
Abstract Infection is one of the most feared hospital-acquired complications. Infusion therapy frequently administered through a central line. Infusions facilitating bacterial growth may be source line-associated bloodstream infections. On other hand, medications that kill bacteria protect against this kind infection and used as catheter lock. In study, we examined impact amiodarone on growth. Amiodarone for controlling cardiac arrhythmias can an infusion weeks. Standard microbiological...
Drugs used in anesthesia may support or inhibit bacterial growth (1), and the ampules syringes we use be contaminated a busy environment (2). IV glyceryl trinitrates (GTN) sodium nitroprusside (SNP), have been for many years (3,4), their therapeutic value as nitric oxide (NO) donors increase future (5). NO can generated during degradation of GTN SNP by tissues (6). also degraded bacteria (7), while is photochemically to (8). with other reactive intermediate nitrates has an antibacterial...
In order to test the advantage of vitamin D(3) preparations in liposomal form, calcitriol, natural activated form D(3), and tacalcitol, a analogue, were employed various concentrations using different vehicles mouse tail test, an animal model for testing antiparakeratotic efficacy topical medications. The optimal concentration petrolatum turned out be similar that commercial preparations. superior those nonliposomal phospholipids. potency (drug activity) tacalcitol 2 microg/g was twice...
Fumaric acid, fumaric acid dimethylester, and the dithranol derivative C4-lactone were studied in mouse tail test to evaluate their effects on epidermal cell differentiation compared with other topical antipsoriatic drugs, such as betamethasone, calcipotriol, dithranol. Mouse tails treated for 2 weeks longitudinal histological sections prepared of skin. The length orthokeratotic regions (stratum granulosum) was measured 10 sequential scales per expressed percentage full scale. In addition,...