A5082808943- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Liver physiology and pathology
- Nutrition and Health in Aging
- Medical Imaging and Analysis
- Bone and Joint Diseases
- Bone health and osteoporosis research
- Bone Metabolism and Diseases
- Pharmacological Effects of Medicinal Plants
- Inflammatory mediators and NSAID effects
- Alcohol Consumption and Health Effects
- Hepatitis B Virus Studies
- Spine and Intervertebral Disc Pathology
- Cancer, Hypoxia, and Metabolism
- GDF15 and Related Biomarkers
- Meta-analysis and systematic reviews
- Total Knee Arthroplasty Outcomes
- Nerve injury and regeneration
- Body Composition Measurement Techniques
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Recycling and utilization of industrial and municipal waste in materials production
- Lower Extremity Biomechanics and Pathologies
- Musculoskeletal pain and rehabilitation
Shanghai University of Traditional Chinese Medicine
2016-2024
Shuguang Hospital
2016-2024
Hunan Academy of Traditional Chinese Medicine
2021-2024
Orthopaedic Hospital
2022
Central Scientific Research Institute of Traumatology and Orthopedics
2021
Zhejiang University
2014
We aimed to investigate the utility of Hounsfield units (HU) obtained from different regions interest in opportunistic lumbar computed tomography (CT) predict osteoporosis coupling with data dual-energy X-ray absorptiometry (DXA).A total 100 patients who attended a university hospital Shanghai, China, and had undergone CT DXA tests spine within 3 months were included this retrospective review. Images reviewed on axial sections, (ROI) markers placed round, oval, anterior, left, right L1-L4...
We assessed the potential of glial cell line-derived neurotrophic factor (GDNF) as a useful biomarker to predict cirrhosis in chronic hepatitis B (CHB) patients.A total 735 patients from two medical centers (385 CHB and 350 healthy controls) were included determine association serum tissue GDNF levels with biopsy-proven cirrhosis. The diagnostic accuracy (sGDNF) was estimated compared other indices cirrhosis.We showed significantly higher sGDNF fibrosis (28.4 pg/ml vs. 11.6 without) (33.8...
The present study intends to investigate the effects and underlying molecular mechanism of Qigu Capsule (QG) on fracture healing in mice with osteoporosis.Ten-week-old female C57BL/6 were ovariectomized three weeks later evaluated for successful modeling. Then, all prepared into models transverse right middle femoral shaft. Mice treated daily using a gavage normal saline (the NS group), QG or alendronate ALN group) postoperatively. Fracture callus tissues collected analyzed by X-ray,...
Abstract Background Dysmobility syndrome based on osteoporosis (ODS) is a disease characterized by low bone mass and muscle mass. Its features are high fracture fall risk. Falls fractures the most important factors affecting quality of life lifespan ODS. However, there no serum marker for evaluation ODS patients. Our previous studies have shown that expression circulating miRNA stable good diagnosis. Therefore, this study aims to explore potential markers Methods A total 78 subjects were...
Background: The influence of patella morphology and horizontal alignment on knee joint kinematics kinetics remains uncertain. This study aimed to assess transverse in relation individuals without conditions. A secondary objective was investigate the impact femur tibia shape gait within this population. Patients methods: We conducted a prospective collection data, including full-leg anteroposterior skyline X-ray views three-dimensional from cohort comprising 54 healthy aged 40 years older....
<title>Abstract</title> Objective Through a systematic review, compare the differences in characteristic indicators of muscle atrophy commonly used mouse models, including mass, strength, fiber cross-sectional area, and genes such as Murf-1 Atrogin-1. Qualitatively quantitatively explore characteristics various models atrophy. Methods A computer search was conducted databases Pubmed, Embase, Cochrane, CNKI, VIP, Wanfang, Sinomed to collect all literature related sarcopenia with time limit...
Alcoholic liver disease (ALD) is associated with high morbidity and mortality worldwide. The pathogenesis of ALD not completely understood. Although accumulating evidence suggests an important role glial cell line-derived neurotrophic factor (GDNF) in several diseases, there are no data concerning its ALD. This study compared patients control subjects used a mouse model culture to investigate the function GDNF mechanism action hepatocyte injury.Serum levels were measured 25 healthy subjects....
Abstract Background Lumbar disc herniation (LDH) is a common chronic musculoskeletal disorder that seriously affects quality of life. The percutaneous endoscopic lumbar diskectomy (PELD) technique was developed to address spinal nerve root compression through direct visualization pathological findings while minimizing tissue destruction upon exposure. It an effective and safe treatment for LDH. However, recurrent LDH major concern after discectomy primary A considerable number clinical...
This study aimed to assess the main components of Artemisia annua L. essential oil (AEO) and determine their effect on proliferation differentiation RAW264.7 cells induced by receptor activator for nuclear factor-ligand (RANKL) in vitro. Then, we tried explain part function its possible mechanisms.Essential was extracted from Osteoclasts were vitro RANKL mouse cells. The experimental group treated with different concentrations AEO, while control not AEO. CCK8 used detect osteoclast...
Abstract We assessed the potential of glial cell line-derived neurotrophic factor (GDNF) as a useful biomarker to predict cirrhosis in chronic hepatitis B (CHB) patients.A total 735 patients from two medical centers (385 CHB and 350 healthy controls) were included determine association serum tissue GDNF levels with biopsy-proven cirrhosis. The diagnostic accuracy (sGDNF) was estimated compared other indices showed significantly higher sGDNF fibrosis (28.4 pg/ml vs. 11.6 without) (33.8 23.5...
The reasonable selection of magnetic resonance imaging(MRI) scan sequence and parameters is very important for the objective evaluation results clinical study high quality imaging. semi quantitative scoring system total knee joint including Whole Organ Magnetic Resonance Imaging Score, Boston Leeds Osteoarthritis Knee MRI Cartilage Repair Score so on. They can fully evaluate imaging changes various organs during development osteoarthritis. With continuous technology, morphological...
Abstract Background We aimed to investigate the utility of Hounsfield units (HU) obtained from different regions interest in opportunistic lumbar computed tomography (CT) predict osteoporosis coupling with data dual-energy X-ray absorptiometry (DXA). Methods 100 patients who attended a university hospital Shanghai, China, and had undergone CT DXA tests spine within 3 months were included this retrospective review. Images reviewed on axial sections, (ROI) markers placed round, oval, anterior,...
Abstract Background: Knee osteoarthritis (KOA), one of the most common degenerative joint disease, is leading cause disability among elder people. Many previous studies demonstrated that Tai chi an effective treatment in management KOA, but there has been a lack study evaluated effect on both clinical and biomechanical outcomes individuals with KOA. The purpose to identify chi, results will help improve understanding possible underlying effects chi. Methods: We conduct prospective,...