A5103070067- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Ion channel regulation and function
- Spinal Fractures and Fixation Techniques
- Osteoarthritis Treatment and Mechanisms
- Connexins and lens biology
- Hearing, Cochlea, Tinnitus, Genetics
- Myofascial pain diagnosis and treatment
- Neuroscience and Neuropharmacology Research
- Bone fractures and treatments
- Lower Extremity Biomechanics and Pathologies
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Healthcare and Venom Research
- Vestibular and auditory disorders
- Cervical and Thoracic Myelopathy
- Engineering Structural Analysis Methods
- Estrogen and related hormone effects
- Force Microscopy Techniques and Applications
- Dyeing and Modifying Textile Fibers
- Parathyroid Disorders and Treatments
- Pain Management and Placebo Effect
- Spinal Hematomas and Complications
- Fatigue and fracture mechanics
- Muscle Physiology and Disorders
Shuguang Hospital
2015-2024
Shanghai University of Traditional Chinese Medicine
2015-2024
Shanghai University
2015-2023
Beijing Anzhen Hospital
2016
Capital Medical University
2016
Zhejiang Sci-Tech University
2015
National University of Defense Technology
2014
College of Charleston
2005
Medical University of South Carolina
2003
Boys Town
1995-1997
Dark cell epithelium secretes K+ into the lumen of vestibular labyrinth by a previously unidentified apical transport mechanism. Previous single-channel patch-clamp studies demonstrated nonselective cation channels and maxi-K+ in membrane, but too low density to account for transepithelial transport. In this report, we with cell-attached macro-patch-clamp technique an outward membrane current at 0-mV pipette voltage, which was stimulated elevating bath concentration from 3.6 25 mM inhibited...
Background Knee Osteoarthritis (KOA) is a prevalent and debilitating condition affecting millions worldwide, yet its underlying etiology remains poorly understood. Recent advances in neuroimaging genetic methodologies offer new avenues to explore the potential neuropsychological contributions KOA. This study aims investigate causal relationships between brain-wide morphometric variations KOA using epidemiology approach. Method Leveraging data from 36,778 UK Biobank participants for human...
To investigate the effects of spinal manipulation (SM) on brain functional activity in patients with lumbar disc herniation (LDH).Eleven LDH were recruited study. All received 6 times SM treatment and then clinical efficacy was evaluated. magnetic resonance imaging (fMRI) scans before after treatment.Three subjects dropped out 8 completed study, among whom 4 cases effective ineffective treatment. The required pressure value producing same level (VAS 50) pain (7.43 ± 1.47) kg (10.53 0.55)...
<sec> <title>BACKGROUND</title> The clinical diagnosis of atlantoaxial joint subluxation (AJS) in traditional Chinese medicine (TCM) is characterized by an unequal distance between the lateral mass atlas and odontoid process on imaging, resulting neck pain accompanied symptoms such as dizziness, headache, limited cervical mobility. In Shanghai, Shi rotational manipulation (SCRM) a commonly employed TCM manual therapy for treating this condition. Nevertheless, there lack evidence-based...
Background: The influence of patella morphology and horizontal alignment on knee joint kinematics kinetics remains uncertain. This study aimed to assess transverse in relation individuals without conditions. A secondary objective was investigate the impact femur tibia shape gait within this population. Patients methods: We conducted a prospective collection data, including full-leg anteroposterior skyline X-ray views three-dimensional from cohort comprising 54 healthy aged 40 years older....
Osteoporosis patients undergoing surgery often have significant bleeding, which is closely related to coagulation function. This study aimed assess the correlation between bone turnover markers (BTMs), mineral density (BMD), and biomarkers. Cases meeting inclusion criteria were included from our center January 2020 December 2021. The relationships biomarkers, BTMs, BMD investigated by Spearman analysis canonical (CCA). Consequently, age, mass stage, 25-hydroxyvitamin D (25-(OH)D), as...
<title>Abstract</title> Objective This study aimed to determine if HBP-A slows down meniscus hypertrophy and mineralization due abnormal mechanical damage the therapeutic effects of are mediated through p38-MAPK signaling pathways. Methods In vivo guinea pig study: Male Hartley pigs underwent anterior cruciate ligament transection (ACLT) on right knee; left knee served as control. Three days after molding, high, medium, low doses were injected into cavity. The injections given twice a week...
The clinical diagnosis of atlantoaxial joint subluxation (AJS) in traditional Chinese medicine (TCM) is characterized by an unequal distance between the lateral mass atlas and odontoid process on imaging, resulting neck pain accompanied symptoms such as dizziness, headache, limited cervical mobility. In Shanghai, Shi rotational manipulation (SCRM) a commonly employed TCM manual therapy for treating this condition. Nevertheless, there lack evidence-based medical information regarding efficacy...
ABSTRACT HBP‐A is the main active component of a traditional Chinese medicine Huaizhen Yanggan Capsule, for remarkable treatment knee osteoarthritis (KOA). This study aimed to elucidate ameliorative effect on meniscus hypertrophy and mineralisation in KOA molecular mechanism its action. An Hartley guinea pig model that underwent anterior cruciate ligament transection (ACLT) rat primary fibrochondrocytes (PMFs) were used investigate meniscal calcification signal transduction The results show...
Abstract Background Lumbar disc herniation (LDH) is a common chronic musculoskeletal disorder that seriously affects quality of life. The percutaneous endoscopic lumbar diskectomy (PELD) technique was developed to address spinal nerve root compression through direct visualization pathological findings while minimizing tissue destruction upon exposure. It an effective and safe treatment for LDH. However, recurrent LDH major concern after discectomy primary A considerable number clinical...
Objective . To compare the immediate and short term effectiveness of Shi’s Daoyin therapy (DT) rather than Melbourne Protocol (MP) in terms pain, mobility, isometric strength cervical muscles nonacute nonspecific neck pain patients. Material Methods A total 114 patients aged 20~50 years were recruited randomly assigned to be treated by either DT or MP. 56 cases 54 received treatment for 3 weeks evaluated before after intervention at 3‐week follow‐up group MP group, respectively. The outcome...
To construct a human cervical spine with bilateral vertebral artery fluid-solid coupling model.Helical CT images under the principle of reverse engineering and meshed in finite element model（FEM） related software were used to establish model. In process modeling body, artery, ligament, intervertebral disc, cartilage endplate large anatomic data cadaver experiments results referenced. From morphology function simulation model real physiological status was tested.The study showed that stress...
Introduction: Skeletal muscle injuries are widespread in sports, traffic accidents and natural disasters some of them with poor prognoses can lead to chronic skeletal damage the clinic. We induced a injury by controlling time contusion force using an acute blunt trauma model that will help us better comprehend pathological features injury. Methods: Several levels were repeatedly striking 5, 10, 15 times gastrocnemius from same height 200 g weights. After injury, markers assessed at 2 4 weeks...
<title>Abstract</title> <bold>Background: </bold> Clinical studies have confirmed that traditional lumbar oblique-pulling manipulation (TLOM) can effectively improve lumbosacral pain caused by sacroiliac joint misalignment. However, the absence of established standards and norms for TLOM, combined with its diverse approaches, increases likelihood deviations in clinical effectiveness potential exacerbation ailment. <bold>Methods: we will use a multicenter, randomized, controlled trial to...