A5100405247- Genomics, phytochemicals, and oxidative stress
- Animal Virus Infections Studies
- Effects of Environmental Stressors on Livestock
- Bone and Dental Protein Studies
- Dietary Effects on Health
- IL-33, ST2, and ILC Pathways
- Adipose Tissue and Metabolism
- Genetic factors in colorectal cancer
- Free Radicals and Antioxidants
- Chromium effects and bioremediation
- Selenium in Biological Systems
- Virus-based gene therapy research
- Phytochemicals and Antioxidant Activities
- Reproductive System and Pregnancy
- Heavy Metal Exposure and Toxicity
- interferon and immune responses
- Viral Infections and Vectors
- Plant Virus Research Studies
Hangzhou Medical College
2024-2025
Zhejiang Provincial People's Hospital
2025
Zhejiang University
2019-2024
Sichuan Agricultural University
2023
Abstract Oxidative stress is a risk factor for mammary health, resulting in decreased milk yield and quality. Application of exogenous bioactive compounds has been research focus antioxidation animals the gland. Quercetin flavonoid extracted from vegetables, fruits tea shown to have variety biological activities, but effect quercetin on redox imbalance epithelial cells unclear. In this study, HC11, mouse cell line, were treated with quercetin, effects molecular mechanisms protection hydrogen...
α-Klotho is an anti-aging protein linked to various age-related diseases. Environmental metal exposure has been associated with oxidative stress and aging, but its effect on levels remains unclear. This study investigated the relationship between urinary concentrations serum using data from National Health Nutrition Examination Survey (NHANES) 2007–2016 cycles. A total of 4071 adults aged 40 79 years were included in analysis. After adjusting for potential confounders, positive associations...
When dairy cows are exposed to high-temperature environment, their antioxidant capacity and productive performance decrease, leading economic losses. Emerging evidence has shown that selenium (Se) can effectively alleviate heat stress in cows; however, the cellular mechanism underlying this protection is not clear. The purpose of study was investigate compare protective effects inorganic Se (sodium selenite, SS) organic (selenite methionine, SM) MAC-T (mammary alveolar cells-large T antigen,...
Because of climate change, heat stress (HS) causes more and impacts on dairy animals to decrease lactation performance. The neuroendocrine system is key in regulating systemic physiological processes milk synthesis. However, the hypothalamic‐pituitary axis response HS still unclear. In this study, a group lactating mice underwent daily 2‐h treatment (36°) for 14 d explore possible cross‐talk between mammary gland under HS. Transcriptome analyses by multitissue RNA‐Seq indicated mechanisms...
Although vaccines play a major role in the prevention of infectious bronchitis (IB), Anti-IB drugs still have great potential poultry production. Radix Isatidis polysaccharide (RIP) is crude extract Banlangen with antioxidant, antibacterial, antiviral, and multiple immunomodulatory functions. The aim this study was to explore innate immune mechanisms responsible for RIP-mediated alleviation virus (IBV)-induced kidney lesions chickens. Specific-pathogen-free (SPF) chicken embryo (CEK) cells...
Our previous study identified the potential of SEMA4B methylation level as a biomarker for hexavalent chromium [Cr(VI)] exposure. This aimed to investigate role gene in Cr(VI)-mediated malignant transformation human bronchial epithelial (BEAS-2B) cells. In our population survey workers, geometric mean [95% confidence intervals (CIs)] Cr blood was 3.80 (0.42, 26.56) μg/L. Following treatment with various doses Cr(VI), it found that 0.5 μM had negligible effects on cell viability BEAS-2B The...
The incidence of mastitis is high during the postpartum stage, which causes severe pain and hinders breast feeding in humans reduces milk production dairy cows. Studies suggested that inflammation multiple organs associated with oxidative stress nuclear factor E2‐related 2 (Nrf2)‐antioxidant response element pathway one most important antioxidant pathways, but effects Nrf2 on antioxidation mammary gland are still unclear. In this study, intramammary lipopolysaccharide (LPS) challenge was...
The S2 subunit serves a crucial role in infectious bronchitis virus (IBV) infection, particularly facilitating membrane fusion. Using reverse genetic techniques, mutant strains of the locus exhibited substantially different syncytium-forming abilities chick embryonic kidney cells. To determine precise formation mechanism syncytium, we demonstrated co-ordinated Abl2 and its mediated cytoskeletal regulatory pathway within subunit. combination fluorescence quantification, RNA silencing, protein...