- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Infectious Diseases and Tuberculosis
- Scoliosis diagnosis and treatment
- Management of metastatic bone disease
- Musculoskeletal pain and rehabilitation
- Hip and Femur Fractures
- Spinal Hematomas and Complications
- Medicinal Plants and Neuroprotection
- Curcumin's Biomedical Applications
- Bone Metabolism and Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Flavonoids in Medical Research
- Spinal Cord Injury Research
- Pharmacological Effects of Medicinal Plants
- Diagnosis and treatment of tuberculosis
- Orthopedic Infections and Treatments
- Mesenchymal stem cell research
- Anesthesia and Pain Management
- Shoulder and Clavicle Injuries
- Bone fractures and treatments
- Cytokine Signaling Pathways and Interactions
Wenzhou Medical University
2011-2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2018-2022
Wenzhou University
2018
State Council of the People's Republic of China
2018
Yahoo (United Kingdom)
2011
Huazhong University of Science and Technology
1999
Study Design Prospective consecutive series. Objective To evaluate the efficacy and safety of percutaneous pedicle screw fixation (PPSF) for thoracolumbar AO type A3 fractures with a specially designed surgical instrument system. Summary Background Data Minimally invasive surgery including PPSF is becoming increasingly widespread in spine surgery. The technique was mostly used as supplemental combined minimally posterior or anterior lumbar interbody fusion management degenerative disorders....
Oxidative stress-induced apoptosis and senescence of nucleus pulposus (NP) cells play a crucial role in the progression intervertebral disc degeneration (IVDD). Accumulation studies has shown that activated autophagy enhanced autophagic flux can alleviate IVDD. In this study, we explored effects apigenin on IVDD vitro vivo. Apigenin was found to inhibit tert-butyl hydroperoxide (TBHP)-induced apoptosis, senescence, ECM degradation NP cells. addition, treatment restore blockage caused by...
Excessive extracellular matrix degradation and chondrocyte apoptosis are the pathological features of osteoarthritis (OA).
• A calcium alginate hydrogel combined with DPSC and FGF21 were synthesized. Ca2+@Alg-FGF21 + promotes the reconnection of spinal cord cross-section. cell migration differentiation. The protects neurons via inhibiting apoptosis promoting autophagy. effectively recovery motor function in HSCI mice. Spinal injury (SCI) often leads to persistent functional deficits due loss glia after injury. Hemisection (HSCI) is a special type SCI. most important difference between SCI occurrence dissection....
Compare the efficacy and safety of minimally invasive open transforaminal lumbar interbody fusion (TLIF) in treatment single segmental spondylolisthesis.From 2010-01 to 2015-10, total, 167 patients with spondylolisthesis treated by TLIF were included, 79 cases (MI-TLIF) group 88 group. The peri-operative parameters operative time, estimated blood loss length postoperative hospital stay was recorded, as well complications. Visual Analogue Scale (VAS) low back pain leg pain, Oswestry...
Surgical techniques and preliminary results.To describe evaluate the safety efficacy of a new minimal invasive technique for irreducible atlantoaxial dislocation (IADD).Endoscope has been widely used in spinal surgery. However, there are no clinical reports regarding anterior approach IADD literature.Ten consecutive patients with were treated by release microendoscopic aide subsequently reduction, transarticular screw fixation morselized autologous bone grafts. There 3 cases odontoid...
We reviewed the outcome of a retrospective case series eight patients with atlantoaxial instability who had been treated by percutaneous anterior transarticular screw fixation and grafting under image-intensifier guidance between December 2005 June 2008. The mean follow-up was 19 months (8 to 27). All solid C1–2 fusion. There were no breakages or displacement screws. pre-operative neck pain immediate relief from their symptoms considerable improvement. major complications. Our preliminary...
Patients with combined C1-2 fractures were often treated by posterior arthrodesis. However, elderly patients multiple injuries (such as brain injury), the large surgical trauma of arthrodesis will increase risk perioperative mortality. A minimally invasive technique may be better for them, and decrease mortality.Seven underwent percutaneous anterior odontoid screw transarticular screws (percutaneous triple fixation). The fixation is described.The operation performed on all successfully...
OBJECTIVE To investigate the therapeutic effects and complications of percutaneous pedicle screw fixation for thoracolumbar fractures. METHODS From January 2002 to December 2008, 103 patients with fractures were treated fixation, including 75 males 28 females, average age was 45.6 years (range, 18 - 72 years). All them no neurological deficits. There 65 cases traffic injury, 23 fall injury 15 smashed injury. According Denis classification, 64 compression fractures, 39 burst 5 had in T(11),...
Background: Anterior cervical discectomy and fusion (ACDF) was almost the “golden standard” technique in treatment of symptomatic degenerative disc disease, however, it cause motion loss indexed level, increase intradiscal pressure adjacent levels, may accelerate degeneration level. Cervical arthroplasty (CDA) designed to preserve index avoid over-activity levels reduce process level is very slowly, long term follow up studies should be conducted, this study aim compare more than 5 years’...