Xiaoping Chen

ORCID: 0000-0002-5894-2661
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About
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Research Areas
  • Peanut Plant Research Studies
  • Coconut Research and Applications
  • Plant Virus Research Studies
  • Metabolism, Diabetes, and Cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Lipoproteins and Cardiovascular Health
  • Diabetes Treatment and Management
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatic function and diabetes
  • Agricultural pest management studies
  • Diabetes Management and Research
  • Pediatric Hepatobiliary Diseases and Treatments
  • Diabetes and associated disorders
  • Cancer, Lipids, and Metabolism
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Traditional Chinese Medicine Studies
  • Organ Transplantation Techniques and Outcomes
  • Nasal Surgery and Airway Studies
  • Iron Metabolism and Disorders
  • Liver Disease and Transplantation
  • Hemoglobinopathies and Related Disorders
  • Chronic Kidney Disease and Diabetes
  • Adipose Tissue and Metabolism
  • Birth, Development, and Health
  • Viral-associated cancers and disorders

China-Japan Friendship Hospital
2014-2024

Huazhong University of Science and Technology
2009-2023

Plastic Surgery Hospital
2013-2023

Tongji Hospital
2015-2023

West China Hospital of Sichuan University
2012-2022

Sichuan University
2012-2022

Zhejiang Hospital
2019

Guangdong Academy of Agricultural Sciences
2008-2019

Soochow University
2017

Second Affiliated Hospital of Soochow University
2017

Lack of sufficient molecular markers hinders current genetic research in peanuts (Arachis hypogaea L.). It is necessary to develop more for potential use peanut research. With the development EST projects, a vast amount available sequence data has been generated. These offered an opportunity identify SSR ESTs by mining. In this study, we investigated 24,238 identification and markers. total, 881 SSRs were identified from 780 SSR-containing unique ESTs. On average, one was found per 7.3 kb...

10.1186/1471-2229-9-35 article EN cc-by BMC Plant Biology 2009-01-01

The influence of glucose and fatty acids on beta-cell function is well established whereas little known about the role amino (AAs).Islets isolated from NMRI mice were incubated overnight. After preincubation, islets as clonal INS-1E beta-cells for 60 min in a modified Krebs Ringer buffer containing AAs.At 16.7 mmol/l (mM) glucose, L-arginine, L-lysine, L-alanine, L-proline, L-leucine, L-glutamine potentiated glucose-stimulated insulin secretion dose-dependently, while DL-homocysteine...

10.1900/rds.2008.5.232 article EN The Review of Diabetic Studies 2008-01-01

Branched-chain amino acids (BCAAs) have generated the most research interest as they emerged potential biomarkers of metabolic disease. BCAAs pathways may also serve targets for treatment type 2 diabetes mellitus. The prevalence is soaring worldwide and now recognized one main threats to human health being associated with comorbidities, such cardiovascular Type a condition characterized by abnormalities in carbohydrate, lipid protein metabolism, characteristic features hyperglycemia...

10.1111/jdi.12345 article EN cc-by-nc-nd Journal of Diabetes Investigation 2015-02-26

Many large-effect quantitative trait loci (QTLs) for yield and disease resistance related traits have been identified in different mapping populations of peanut (Arachis hypogaea L.) under multiple environments. However, only a limited number QTLs used marker-assisted selection (MAS) because unfavorable epistatic interactions between genetic backgrounds. Thus, it is essential to identify consensus across environments backgrounds use MAS. Here, we QTL meta-analysis set peanut.A new integrated...

10.1186/s12864-018-5288-3 article EN cc-by BMC Genomics 2018-12-01

Microsatellites, or simple sequence repeats (SSRs), represent important DNA variations that are widely distributed across the entire plant genome and can be used to develop SSR markers, which then conduct genetic analyses molecular breeding. Cultivated peanut (A. hypogaea L.), an oil crop worldwide, is allotetraploid (AABB, 2n = 4× 40) species. Because of its complex genome, genomic marker development has been very challenging. However, sequencing cultivated allowed us markers construct a...

10.1186/s12864-019-6148-5 article EN cc-by BMC Genomics 2019-11-01

Septal extension graft is an effective procedure in tip plasty because it can provide stable structural support for the nasal tip. However, Asian patients septal cartilage much weaker, thinner, and smaller than that of white people, causing existing caudal to deviate opposite side placement.To introduce reliable modified plasty.Observational study a total 143 (84 undergoing primary rhinoplasty 59 secondary rhinoplasty).A technique combination with other procedures, including implant...

10.1001/jamafacial.2013.1285 article EN JAMA Facial Plastic Surgery 2013-07-29

The aim of the present study was to evaluate efficacy and safety polyethylene glycol loxenatide (PEX168) injections in Chinese type 2 diabetic (T2D) patients.The multicenter randomized double-blind parallel placebo-controlled clinical trial enrolled patients who had been treated with a stable dose metformin (≥1500 mg/day) for ≥12 weeks an HbA1c level between 7% 11%. Subjects were randomly divided into three groups (1: 1: 1) once weekly subcutaneous either placebo or 100 200 μg PEX168 12...

10.1111/1753-0407.12397 article EN Journal of Diabetes 2016-03-19

Hepatic splenosis, one type of manifestation ectopic spleen tissue, is rarely reported. It cannot be distinguished from hepatic malignancies because lack significant radiological features. By means this case report and 31 literature reviews, potential treatment modalities concerning clinical diagnostics, patient's management could discussed. The presents the a 33-year-old man with liver lesion. Finally, after mini-incision laparotomy, lesion was resected diagnosis confirmed it as splenosis....

10.1097/md.0000000000000586 article EN cc-by-nc Medicine 2015-03-01

Abstract Background We aimed to explore if hyperglycaemia and hyperinsulinemia in the diabetes prediabetes population were associated with increased risk of cancer occurence. Methods Overall, 1700 participants different glycaemic statuses screened from 110,660 residents Da-Qing, China, 1985. They followed up 30 years access outcomes. Results Cancer was identified 15.2% (259/1700) participants. The incidence normal glucose tolerance (NGT), impaired (IGT) groups 6.06, 6.77, 7.18 per 1000...

10.1038/s41416-022-01758-x article EN cc-by British Journal of Cancer 2022-03-07

Background Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim this study was explore if the antihyperglycemic agent, Isosteviol (ISV), is able counteract palmitate-induced α-cell dysfunction influence gene expression. Methodology/Principal Findings incubation studies with clonal α-TC1–6 cells were performed in presence 0.5 mM palmitate or without ISV. We investigated effects on secretion, content, cellular triglyceride (TG)...

10.1371/journal.pone.0034361 article EN cc-by PLoS ONE 2012-03-27

To validate the prognostic significance of preoperative serum iron metabolism parameters in non-metastatic colorectal cancer patients treated with curative resection. Methods: We conducted a prospective cohort study Department Surgical Oncology, WuXi 4th People's Hospital, WuxiChina, between March 2010 and September 2013. The relationships other variables were examined. was evaluated using Kaplan Meier curve Cox proportional hazards regression model. Results: Five hundred fourteen eligible...

10.15537/smj.2017.3.16110 article EN Saudi Medical Journal 2017-02-22

To investigate the differential effects of maternal versus paternal history diabetes on risks for and prediabetes, as well insulin secretion resistance in Chinese individuals.From 2007 to 2008 China National Diabetes Metabolism Disorders Study, 39,244 participants were included divided into four categories: negative parental history, only (PH), (MH), both history.The age- sex-standardized prevalence rates PH, MH, groups 8.59, 12.56, 15.86 29.81%, respectively. The impaired glucose metabolism...

10.1111/jdi.13360 article EN cc-by-nc Journal of Diabetes Investigation 2020-07-18

// Danyan Xu 1,* , Jiahui Hu Qinghua Wu 2 Zhiming Du 3 Yusheng Xue 4 Zhang 5 Yi Li 6 Yushan Chen 7 Xiaoping 8 Hong 9 and Shuiping Zhao 10 1 Department of Cardiology, the Second Xiangya Hospital Central South University, Changsha, P.R. China Affiliated Nanchang Nanchang, First Sun Yat-sen Guangzhou, Tangdu Hospital, Xi'an, Chinese Medicine, Huadong to Fudan Shanghai, Beijing Beijing, Center Henan University TCM, Zhengzhou, West Sichuan Chengdu, People's Yunnan, Kunming, * These authors were...

10.18632/oncotarget.18329 article EN Oncotarget 2017-06-01

Background. To assess the association of metformin monotherapy with risk all-cause deaths and cardiovascular events in type 2 diabetes patients real clinical practice. Methods. This retrospective, observational study comprised initially treated or nonmetformin over 2011-2016. Data were extracted from National Healthcare Big database Fuzhou, China. Propensity score matching (PSM) was performed, each patient on to one terms a set covariates. The primary endpoint death, secondary endpoints...

10.1155/2021/5534387 article EN cc-by Journal of Diabetes Research 2021-06-10

Solitary hepatic lymphangioma mimicking liver malignancy: A case report and literature review

10.12998/wjcc.v8.i19.4633 article EN World Journal of Clinical Cases 2020-09-25

The nasolabial folds (NLFs) may be shallowed with the use of nostril base augmentation. This study aimed to design and customize patient-specific implants (PSIs) computer-aided design/computer-aided manufacturing (CAD/CAM) correct NLF deepening caused by midfacial aging. patient's head computed tomography data obtained were used for reconstruction. PSIs customized CAD/CAM techniques, which implanted into a nasal shallow NLFs Preoperative postoperative photos wrinkle severity rating scale...

10.1097/scs.0000000000009269 article EN Journal of Craniofacial Surgery 2023-03-30
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