- Neuroscience and Neuropharmacology Research
- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- Receptor Mechanisms and Signaling
- Infant Development and Preterm Care
- Biochemical Analysis and Sensing Techniques
- Neuropeptides and Animal Physiology
- Stress Responses and Cortisol
- Retinopathy of Prematurity Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neonatal Health and Biochemistry
- Childhood Cancer Survivors' Quality of Life
- Child and Adolescent Health
- Advanced Fluorescence Microscopy Techniques
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroendocrine regulation and behavior
- Genetics and Neurodevelopmental Disorders
- Circadian rhythm and melatonin
- Trauma Management and Diagnosis
- Neural dynamics and brain function
- Single-cell and spatial transcriptomics
- Soft tissue tumors and treatment
- Vehicle License Plate Recognition
- Neuroblastoma Research and Treatments
All India Institute of Medical Sciences
2013-2024
Graphic Era University
2024
Indian Space Research Organisation
2024
All India Institute of Medical Sciences, Deoghar
2024
Post Graduate Institute of Medical Education and Research
2024
Creative Commons
2023
University of Michigan
1985-2023
Chandigarh University
2023
All India Institute of Medical Sciences, Nagpur
2023
Mayo Clinic
2006-2008
Background: Diagnosing sepsis in preterm neonates is a significant challenge, underscoring the urgent need for timely and accurate methods. Serum inflammatory protein signatures show promising potential early precise disease diagnosis. Methods: In this study, cohort of (n=50, 25-35 weeks gestation, female 40%) at time suspicion follow-up were enrolled along with healthy neonates. Based on clinical presentation blood culture or MALDI results, cases categorized into culture-positive...
Prenatal auditory stimulation in chicks with species-specific sound and music at 65 dB facilitates spatial orientation learning is associated significant morphological biochemical changes the hippocampus brainstem nuclei. Increased noradrenaline level due to physiological arousal suggested as a possible mediator for observed beneficial effects following patterned rhythmic exposure. However, studies regarding of prenatal high decibel (110 dB; noise) exposure on plasma level, synaptic protein...
Significance The interplay between the anorexigenic and orexigenic neurons in arcuate nucleus that contributes to control of feeding remains elusive. Using optogenetic stimulation, we show activation POMC rapidly inhibits behavior fasted animals. However, simultaneous stimulation both a subset express AgRP is sufficient reverse inhibition trigger intense behavior. We used 3D imaging functional studies illuminate anatomical underpinning inhibitory excitatory events. Our work suggests...
Although the sensory and motor roles of purinergic system in bladder are well proven animal species, there is increasing evidence that it may have an important role humans. In addition, be pathophysiology dysfunction. We established level adenosine triphosphate (ATP) release from porcine normal human bladders.Bladder strips patients with a urodynamically stable undergoing surgery for stress incontinence those cystectomy cancer no lower urinary tract symptoms were subjected to varying degrees...
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models opioid-related behaviors, circuit mechanisms MOR-expressing cells are less known because a lack genetic tools to selectively manipulate them. We introduce CRISPR-based Oprm1-Cre knock-in transgenic that provides cell type-specific access cells. After performing anatomic behavioral validation experiments, we used rats study involvement NAc heroin...
Background The origin of advanced arterial and renal calcification remains poorly understood. Self-replicating, calcifying entities have been detected isolated from calcified human tissues, including blood vessels kidney stones, are referred to as nanobacteria. However, the microbiologic nature putative nanobacteria continues be debated, in part because difficulty discriminating biomineralized microbes minerals nucleated on anything else (eg, macromolecules, cell membranes). To address this...
Emotions are characterized not only by their valence but also whether they stable or labile. Yet, we do understand the molecular circuit mechanisms that control dynamic nature of emotional responses. We have shown glucocorticoid receptor overexpression in forebrain (GRov) leads to a highly reactive mouse with increased anxiety behavior coupled greater swings This phenotype is established early development and persists into adulthood. However, neural circuitry mediating this lifelong lability...
Abstract Introduction Children ≤5 years of age with Ewing's sarcoma (ES) possibly have a distinct disease biology, data on which are scarce. We evaluated clinical features, outcomes, and prognostic factors ES among children years. Methods registered between 2003 2019 were included. Baseline treatment details retrieved from medical records. Prognostic identified using multivariable Cox regression. Clinical features outcomes compared those greater than 5 by chi‐square log‐rank tests....
Kikuchi-Fujimoto disease is a rare, benign, and self-limiting condition that mostly affects young females. Cervical lymphadenopathy with fever the most common presentation of disease. It may have unusual presentations can lead to diagnostic dilemma delay in diagnosis. We report case 25-year-old female who presented relapsing cervical lymphadenopathy. Because atypical presentation, there was diagnosis increase morbidity. High index suspicion collaboration between clinicians pathologists...