A5072436087- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Bacterial Infections and Vaccines
- Pharmaceutical and Antibiotic Environmental Impacts
- Immune responses and vaccinations
- Microbial bioremediation and biosurfactants
- Probiotics and Fermented Foods
- Biochemical and Structural Characterization
- Ethnobotanical and Medicinal Plants Studies
- Microbial Community Ecology and Physiology
- Chemotherapy-induced cardiotoxicity and mitigation
- Protein Hydrolysis and Bioactive Peptides
- Bacteriophages and microbial interactions
- Biofuel production and bioconversion
- Immune Response and Inflammation
- Silicon Carbide Semiconductor Technologies
- Antibiotic Use and Resistance
- Pesticide and Herbicide Environmental Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Immunodeficiency and Autoimmune Disorders
- Mesenchymal stem cell research
- Essential Oils and Antimicrobial Activity
- Composting and Vermicomposting Techniques
- Enzyme Production and Characterization
- Bacterial Identification and Susceptibility Testing
October 6 University
2020-2023
Beni-Suef University
2012-2022
Benha University
2021-2022
Abstract Background Diabetic foot ulceration is a serious chronic complication of diabetes mellitus characterized by high disability, mortality, and morbidity. Platelet-rich plasma (PRP) has been widely used for diabetic wound healing due to its content growth factors. However, application limited the rapid degradation The present study aimed evaluate efficacy combined adipose-derived mesenchymal stem cells (ADSCs) PRP therapy in promoting relation Notch signaling pathway. Methods Albino...
Onion peels are often discarded, representing an unlimited amount of food by-products; however, they a valuable source bioactive phenolics. Thus, we utilized UPLC-MS/MS to analyze the metabolomic profiles red (RO) and yellow (YO) onion peel extracts. The cytotoxic (SRB assay), anti-inflammatory (Griess antimicrobial (sensitivity test, MIC, antibiofilm, SP-SDS tests) properties were assessed in vitro. Additionally, histological analysis, immunohistochemistry, ELISA tests conducted investigate...
Background: Multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Pseudomonas aeruginosa are the leading cause healthcare-associated infections worldwide. Objective: The aim was to identify resistant phenotypes among P. characterize different aminoglycosides carbapenem resistance genes as major mechanisms in these isolates, Theodor Bilharz Research Institute (TBRI), a tertiary care hospital Cairo, Egypt. Methods: During period 11 months, 42 clinical isolates were...
The effect of levofloxacin (LEV) and vitamin-C (VIT-C) individually or in combinations on initial bacterial adherence pre-formed (mature) biofilms the surface urethral catheters was studied.The isolated studied uropathogens present study showed considerable diversity, where major pathogens were identified as E.coli, Klebsiella sp., Citrobacter Enterobacter Proteus sp. Pseudomonas sp.Using static assay, addition LEV VIT-C each alone at sub MIC concentrations (0.25 0.5 MIC) (80 100 mg ml-1)...
Trastuzumab (Trz) is a humanized monoclonal antibody targeting epidermal growth factor receptor 2 (HER2; ErbB2). The combined administration of Trz and doxorubicin (DOX) has shown potent anti-cancer efficacy; however, this regimen may be accompanied by severe cardiac toxicity. Mesenchymal stem cells (MSCs)-derived exosomes are nanosized vesicles that play crucial role in cell-cell communication have efficacy the treatment various diseases. In study, we aim to investigate cardioprotective...
Abstract Aims Lower respiratory tract infections (LRTIs) have been identified by the World Health Organization as most deadly infectious diseases and a pervasive public health problem, causing increased hospital admissions, mortality antibiotic use. This study aims to determine common resistant bacteria that cause LRTIs prepare an appropriate vaccine reduce prevent potential future infections. Methods Results Our survey was conducted collecting exudate specimens. The predominant types were...
This study aimed to highlight the importance of compost from aromatic plants as a stunning source for several bio active compounds generated their inhabited thermophilic bacteria. Some isolated could have potential role in treatment microbial infections.A total forty different bacteria were samples during stage. These isolates tested antimicrobial capabilities against Gram-positive and -negative using agar diffusion double layer methods. The further identified based on morphological,...
Thevetia peruviana and Plumeria rubra (family Apocyanaceae) are shrubs cultivated in Egypt for ornamental purposes.This study was done to compare the volatile oils of T. P. which were prepared by using hydrodistillation method from fresh flowers leaves each plant.Identification quantification oil components carried out GC/MS analysis.The major Nonadecane (37.69 %), followed 1-Nonylcycloheptane (18.39%), while Perilla alcohol (20.49%), β-ylangene(10.62%) β-Elemene (7.19%) predominant oil.On...
Aromatic amines are potential mutagens and carcinogens, so biodegradation of them may protect our environment by safely getting rid these compounds.In the present study, 5 aniline degrading isolates were recovered from 30 samples sewage agricultural wastewater, The five identified biochemically 16S rRNA gene sequence analysis as Achromobacter sp.(2 isolates), Pseudomonas isolates) Enterobacter sp.(1 isolate).Biodegradation was measured HPLC, within 10 days, degradation percentage variable...
Bacterial infection poses a serious threat to human life due the rapidly growing resistance of bacteria antibacterial drugs, which is significant public health issue. This study was focused on design and synthesis new series 25 analogues bearing 5-cyano-6-oxo-4-substituted phenyl-1,6-dihydropyrimidine scaffold hybridized with different substituted benzenesulfonamides through thioacetamide linker M1–25. The antimicrobial activity molecules studied against various Gram-positive, Gram-negative,...
Background: Cellulose, the major component of plant cell wall, is most abundant and cheap polymer on earth. It can be used by varieties cellulolytic enzymes. Cellulases hydrolyze cellulose to its glucose monomers, which fermented many biotechnological products, such as biochemicals, bioplastics, biofuels. Actinomycetes are potential sources cellulases. Objective: The current study sheds light activity Thermobifida cellulosilytica , a previously isolated thermophilic actinomycete, analysis...
Biosurfactant producing bacteria (28 isolates) were isolated from 30 oil contaminated soils and tested for production of biosurfactant by different screening methods.About 75% the showed no blood hemolysis their emulsification index hexane xylene ranges 28-35% 30-45% respectively.Biosurfactant ability was confirmed other tests where about 40% isolates positive spreading activity, hydrocarbon overlay 67% to be drop collapsing test.16s RNA sequencing most active revealed one Stenotrophomonas...
Antimicrobial resistance gene profile characterization and dissemination offer useful detail on the possible challenge in treating bacteria. The development of aminoglycoside modifying enzymes (AMEs) is considered as primary mechanism to aminoglycosides, addition 16S rRNA methylases. This study aimed at isolation aminoglycosides resistant clinical isolates enterobacteriaceae family from different samples. Over a period 24 months, thirty samples were collected 49 E. coli [n=25], Klebsiella...
Bacillus Calmette-Guerin (BCG) and polysaccharide meningococcal (pMen) vaccines are required to travel some countries, medical staff deal with disease carriers, for special cases as well. However, there were not enough studies on the immunogenic intervention between them when given together or in combination. Hence, we tried assess antibody-mediated immune response groups of mice different BCG pMen combined together, either concurrently a 14-day break them. The antibody titer was measured...