A5045332098- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Tracheal and airway disorders
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Bacterial Infections and Vaccines
- Viral gastroenteritis research and epidemiology
- Diabetes and associated disorders
- Respiratory Support and Mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diet and metabolism studies
- Emergency and Acute Care Studies
- Pancreatic function and diabetes
- Infective Endocarditis Diagnosis and Management
- COVID-19 Impact on Reproduction
- COVID-19 and healthcare impacts
- Multiple and Secondary Primary Cancers
- Cancer and Skin Lesions
Norwegian Institute of Public Health
2012-2025
Nasjonalforeningen for Folkehelsen
2024
Office of Readiness and Response
2022
Division of Chemistry
2012
We included 39,524 COVID-19 Omicron and 51,481 Delta cases reported in Norway from December 2021 to January 2022. estimated a 73% reduced risk of hospitalisation (adjusted hazard ratio: 0.27; 95% confidence interval: 0.20-0.36) for compared with Delta. Compared unvaccinated groups, who had completed primary two-dose vaccination 7-179 days before diagnosis lower than (66% vs 93%). People vaccinated three doses similar reduction (86% 88%).
Abstract Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in adults that can result hospitalizations. Estimating RSV-associated hospitalization critical for planning RSV-related healthcare across Europe. Methods We gathered estimates from the RSV Consortium Europe (RESCEU) Denmark, England, Finland, Norway, Netherlands, and Scotland 2006 to 2017. extrapolated these 28 European Union (EU) countries using nearest-neighbor matching, multiple...
Abstract Background Knowledge on age-specific hospitalizations associated with RSV infection is limited due to testing, especially in older children and adults whom infections are not expected be severe. Burden estimates based coding of hospital admissions known underestimate the burden RSV. We aimed provide robust reliable RSV-associated data respiratory from national health registers laboratory-confirmed cases Methods conducted multiseason regression analysis weekly influenza as...
At the end of 2022 and most notably during first half 2023, number invasive group A streptococcus (iGAS) notifications increased in Norway, largely affecting children younger than 10 years, as observed several other countries. Following this atypical season, a new surge iGAS began December 2023 peaked between January February 2024, now particularly both years older adults (70 above).
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection (RTI) in young children. Registries provide opportunities to explore RSV epidemiology and burden. Methods We explored routinely collected hospital data on children aged < 5 years 7 European countries. compare RSV-associated admission rates, age, seasonality, time trends between Results found similar age distributions admissions each country, with the highest burden 1 old peak at...
Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infections and hospitalisations among young children globally responsible for many deaths in children, especially infants aged <6 months. Furthermore, RSV severe disease hospitalisation older adults. The development new candidate vaccines monoclonal antibodies highlights the need reliable surveillance RSV. In European Union (EU), no up-to-date general recommendations on are currently available. Based...
Since their emergence, SARS-CoV-2 variants of concern (VOC) B.1.1.7 and B.1.351 have spread worldwide. We estimated the risk hospitalisation admission to an intensive care unit (ICU) for infections with in Norway, compared non-VOC.Using linked individual-level data from national registries, we conducted a cohort study on laboratory-confirmed cases Norway diagnosed between 28 December 2020 2 May 2021. Variants were identified based whole genome sequencing, partial sequencing by Sanger or PCR...
OBJECTIVES There is limited evidence on whether the relative severity of coronavirus disease 2019 (COVID-19) in children and adolescents differs for different severe acute respiratory syndrome 2 variants. We compare risk hospitalization to COVID-19 or multisystem inflammatory (MIS-C) among unvaccinated persons &lt;18 years with (cases) between waves Alpha, Delta, Omicron (sublineage BA.1) variants Norway. METHODS used linked individual-level data from national registries calculate...
We estimated the BNT162b2 vaccine effectiveness (VE) against any (symptomatic or not) SARS-CoV-2 Delta and Omicron infection among adolescents (aged 12-17 years) in Norway from August 2021 to January 2022.We used Cox proportional hazard models, where status was included as a time-varying covariate models were adjusted for age, sex, comorbidities, residence county, birth country, living conditions.The VE peaked at 68% (95% confidence interval [CI]: 64-71%) 62% CI: 57-66%) days 21-48 after...
Abstract Background SARS-CoV-2 reinfection rates have been shown to vary depending on the circulating variant, vaccination status and background immunity, as well time interval used identify reinfections. This study describes frequency of reinfections in Norway using different intervals assesses potential factors that could impact risk during variant waves. Methods We linked individual-level data from national registries conduct a retrospective cohort including all cases with positive test...
To estimate the risk of hospitalization among reported cases Delta variant severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) compared with Alpha in Norway, and by vaccination status.A cohort study was conducted on laboratory-confirmed SARS-CoV-2 diagnosed between 3 May 15 August 2021. Adjusted ratios (aRR) 95% confidence intervals (CI) were calculated using multi-variable log-binomial regression, accounting for variant, status, demographic characteristics, week sampling underlying...
ABSTRACT Background In 2021, the Norwegian Institute of Public Health established temporary registry‐based surveillance severe acute respiratory infections (SARI). We aimed to describe system and evaluate selected attributes inform establishment a permanent SARI system. Methods cases were defined using ICD‐10 discharge codes from national health administrative registries, including for upper or lower infection (URI LRI), COVID‐19, distress syndrome, pertussis otitis media. Data polymerase...
Background: Many countries reported missing and atypical influenza RSV seasons during the COVID-19 pandemic. Here we describe incidence seasonality of COVID-19, influenza, hospitalizations in Norway between 2017-2024, disease burden 2022-2024. Methods: Using nationwide data on ICD-10 discharge codes, procedure codes laboratory results, calculate hospitalizations, by age group, week season January 2017 to April 2024, report proportions receiving intensive care, proportion deaths length stay...
Abstract Background COVID-19 vaccination was recommended for adolescents in Norway since August 2021. In this population-based cohort study, we estimated the BNT162b2 vaccine effectiveness against any PCR-confirmed (symptomatic or not) SARS-CoV-2 infections caused by Delta and Omicron variant among (12-17-years-old) from 2021 to January 2022. Methods Using Cox proportional hazard models, infections. Vaccine status included as a time-varying covariate models were adjusted age, sex,...
Whether the SARS-CoV-2 mRNA vaccines may cause a transient increased stroke risk is uncertain.In registry-based cohort of all adult residents at December 27, 2020, in Norway, we linked individual-level data on COVID-19 vaccination, positive test, hospital admissions, death, health care worker status, and nursing home resident status extracted from Emergency Preparedness Register for Norway. The was followed incident intracerebral bleeding, ischemic stroke, subarachnoid hemorrhage within...
Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infections (RTIs) in young children. High-quality country-specific estimates bed days and length stay (LOS) show the population burden RSV-RTI on secondary care services among patients, can be used to inform RSV immunization implementation decisions.We estimated hospital RSV-associated RTI (RSV-RTI) children under 5 years 7 European countries (Finland, Denmark, Norway, Scotland, England, Netherlands, Italy) using...
To evaluate risk factors for severe disease in children under 59 months of age hospitalized with respiratory syncytial virus (RSV) infection.We prospectively enrolled 1,096 cases laboratory confirmed RSV infection during three consecutive seasons 2015-2018. Potential were retrieved through patient questionnaires and linkage to national health registries. Need support (invasive ventilation, bi-level positive airway pressure, or continuous pressure), length stay exceeding 72 h used as measures...
The prevalence of Enterobius vermicularis in neighboring countries Norway show large variation. goal this study was to investigate the among Norwegian children and possible risk factors.The were participants "Environmental Triggers Type 1 Diabetes: MIDIA study." involved 2 groups with different genetic risks type diabetes: A high-risk group carries Human Leukocyte Antigen genotype conferring highest for diabetes a nonhigh-risk consisting without genotype. Scotch tape samples collected on 3...
Using individual-level national registry data, we conducted a cohort study to estimate differences in the length of hospital stay, and risk admission an intensive care unit in-hospital death among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant, compared Delta variant Norway. We included 409 (38%) 666 (62%) who were hospitalised disease 2019 (COVID-19) as main cause hospitalisation between 6 December 2021 February 2022. had 48% lower...
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of respiratory tract illness in young children and major hospital admissions globally. Methods Here we fit age-structured transmission models with immunity propagation to data from the Netherlands (2012–2017). Data included nationwide hospitalizations confirmed RSV, general practitioner (GP) on attendance for care acute infection, virological testing infections at GP. The models, equipped key parameter estimates, were...
Bronchiolitis is the commonest cause of respiratory related hospital admissions in young children. This study aimed to describe temporal trends bronchiolitis for children under 2 years age Scotland by patient characteristics, socioeconomic deprivation, and duration admission.The national database was used extract data on all (International Classification Disease, Tenth Revision, code J21) <2 from 2001 2016. Deprivation quintiles were classified using 2011 Scottish Index Multiple...