A5038222792- Thyroid Cancer Diagnosis and Treatment
- Laser-Plasma Interactions and Diagnostics
- Nuclear Physics and Applications
- Ovarian cancer diagnosis and treatment
- Laser-induced spectroscopy and plasma
- Air Quality Monitoring and Forecasting
- Breast Lesions and Carcinomas
- Air Quality and Health Impacts
- Optical Imaging and Spectroscopy Techniques
- Atomic and Subatomic Physics Research
- Radiation Dose and Imaging
- Atmospheric aerosols and clouds
- Radiomics and Machine Learning in Medical Imaging
- Immunotherapy and Immune Responses
- Energetic Materials and Combustion
- Random lasers and scattering media
- Nuclear reactor physics and engineering
- Breast Cancer Treatment Studies
- Combustion and Detonation Processes
- Ion-surface interactions and analysis
- High-pressure geophysics and materials
- MRI in cancer diagnosis
- RNA Interference and Gene Delivery
- Atmospheric chemistry and aerosols
- Plasma Diagnostics and Applications
University of Chinese Academy of Sciences
2021-2023
Institute of Urban Environment
2023
Chinese Academy of Sciences
2022-2023
Zhejiang Cancer Hospital
2020-2023
China Academy of Engineering Physics
2011-2022
Cancer Hospital of Chinese Academy of Medical Sciences
2021-2022
Institute of Chemistry
2022
Institute of Applied Physics and Computational Mathematics
2020
Nanovaccines have emerged as promising alternatives or complements to conventional cancer treatments. Despite the progresses, specific co-delivery of antigen and adjuvant their corresponding intracellular destinations for maximizing activation antitumor immune responses remains a challenge. Herein, lipid-coated iron oxide nanoparticle is delivered nanovaccine (IONP-C/O@LP) that can co-deliver peptide (CpG DNA) into cytosol lysosomes dendritic cells (DCs) through both membrane fusion...
Although the fundamental mechanisms of atmospheric new particle formation events are largely associated with gaseous sulfuric acid monomer (SA), parameters affecting SA generation and elimination remain unclear, especially in coastal areas where certain sulfur-containing precursors abundant. In this study, we utilized machine learning (ML) combination field observations to map link between influencing parameters. The developed random forest (RF) model performed well creating simulations an...
To establish and validate a nomogram model, which can incorporate clinical data, imaging features of ultrasound (US) contrast-enhanced (CEUS), for improving the diagnostic efficiency solid breast lesions.A total 493 patients with lesions were randomly divided into training (n = 345) validation 148) cohorts ratio 7:3 and, data image US CEUS reviewed retrospectively analyzed. The in both analyzed using BI-RADS models.Five variables, including shape calcification conventional US, enhancement...
Abstract Background Primary thyroid lymphoma (PTL) and papillary carcinoma (PTC) are both malignancies, but their therapeutic methods prognosis different. This study aims to explore sonographic computed tomography(CT)features, improve the early diagnosis rate. Methods The clinical imaging data of 50 patients with non-diffuse PTL 100 PTC confirmed by pathology were retrospectively analysed. Results Of 150 patients, from perspective data, between existed significant difference in age, maximum...
Low-mode asymmetry is known to be a main source of yield degradation in implosion experiments performed at the National Ignition Facility Lawrence Livermore Laboratory. In this paper, we present theoretical model deceleration phase investigate low-mode asymmetries, which derived by considering fuel layer composed thin shell pieces and neglecting interaction between these longitudinal direction. The able characterize evolution asymmetries assess corresponding performance degradation, as...
To investigate ultrasound appearance and the survival outcomes for patients with primary thyroid lymphoma (PTL).Ultrasonic images clinical characteristics from pathologically confirmed 69 PTL (2008-2019) were retrospectively analyzed. The characteristics, ultrasonic characters, prognostic factors Survival curves plotted using Kaplan-Meier method. Univariate multivariate analyses performed.Of study patients, 23 indolent 46 aggressive PTL. Age (>70 years old) elevated lactate dehydrogenase...
Abstract The spherically convergent plasma fusion (SCPF) scheme is a robust approach to provide high-brightness pulsed neutron source. performance of the SCPF driven by long-pulsed laser investigated. experiments, with pulse duration in range 0.5 ns 3 ns, were implemented on ShenGuang-II Upgrade facility and 100 kJ level facility. intensity beam was about multiple 10 14 W cm −2 . measured D–D reaction yields 7.3 × 8 1.01 11 , while energies 2.1 100.5 kJ. temporal self-emitted x-ray flux...
We study stochastic radiation transport through random media in one dimension, particular for pure absorbing cases. The statistical model to calculate the ensemble-averaged transmission a binary mixture is derived based on cumulative probability density function (PDF) of optical depth, which numerically simulated both Markovian and non-Markovian mixtures by Monte Carlo calculations. present systematic results about influence mixtures' stochasticity transport. It found that mixing statistics...
Abstract Background Papillary thyroid carcinoma (PTC) is the most common carcinoma, which prone to cervical lymph node metastasis (CLNM). We aim analyze correlation between clinical information, ultrasonic (US) measurements of PTC and CLNM. Methods A total 1335 patients who underwent thyroidectomy had pathologically confirmed unifocal were enrolled in retrospective research. Univariate analysis logistic performed predict CLNM PTC. Receiver operating characteristic (ROC) curve was used...
The burst initiation time and emission rate of delayed neutrons for the Godiva I assembly in presence a weak neutron source, which is 5[c-slash] above prompt criticality, were calculated using an analog Monte Carlo method. simulation consistent with result experiment. included, extended probability model derived based on point kinetics, well explains experimental measurement.
In laser-driven fusion, determining the ignition margin is an important prerequisite for evaluating robustness of a target design. The threshold factor (ITF), defined as shell kinetic energy at time maximum implosion velocity divided by minimum capsule, widely adopted specific metric margin. this paper, in contrast to previous definitions ITF, additional quantity, i.e., aspect ratio (Ar) time, found have influence on With including quantity Ar, we obtained extended ITF through statistical...
Abstract Purpose: The current study aims to explore diagnostic value of the thyroid imaging, reporting and data system (TI-RADS) published by American College Radiology (ACR) on different-sized nodules. Methods: A total 1183 nodules were selected from 952 patients with confirmed surgical pathology January 2021 October 2022. Based maximum diameters nodules, they stratified into groups (≤ 10 mm), B (> mm, < 20 mm) C (≥ mm). ultrasonic features in each group evaluated scored based ACR...
In inertial confinement fusion, the ignition threshold factor (ITF), defined as ratio of available shell kinetic energy to minimum energy, is an important metric for quantifying how far implosion from its performance cliff. Traditional ITF research based on analytical theories with explicit scaling laws and parameters obtained by numerically fitting simulation data. This present study uses machine learning (ML) methods train implicit but more reliable expressions. One-dimensional numerical...
Abstract Objective Papillary thyroid carcinoma (PTC) is the most common carcinoma, and prone to cervical lymph node metastasis (CLNM). We aim analyze correlation between clinical information, ultrasonic parameters of PTC CLNM. Methods 1335 patients who had pathologically confirmed unifocal were enrolled. Univariate multivariate logistic analysis performed predict CLNM in patients. The receiver operating characteristic (ROC) curve was used evaluate diagnostic performance. Results showed that...