Nobuyuki P. Aoki

ORCID: 0000-0002-5928-5931
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About
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Research Areas
  • Glycosylation and Glycoproteins Research
  • Genomics and Phylogenetic Studies
  • Carbohydrate Chemistry and Synthesis
  • Advanced Proteomics Techniques and Applications
  • Enzyme Production and Characterization
  • Scientific Computing and Data Management
  • Biomedical Text Mining and Ontologies
  • Nanofabrication and Lithography Techniques
  • Visual perception and processing mechanisms
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Orbital Angular Momentum in Optics
  • Nanocluster Synthesis and Applications
  • Genetics, Bioinformatics, and Biomedical Research
  • Research Data Management Practices
  • Molecular Biology Techniques and Applications
  • Ion-surface interactions and analysis
  • Near-Field Optical Microscopy
  • Advanced Nanomaterials in Catalysis
  • Electron and X-Ray Spectroscopy Techniques
  • Skin Protection and Aging
  • Impact of Light on Environment and Health

Soka University
2015-2024

Chiba University
2000-2024

Soka University of America
2020

University of Tokyo Hospital
2007

Rapid and continued growth in the generation of glycomic data has revealed need for enhanced development basic infrastructure presenting interpreting these datasets a manner that engages broader biomedical research community. Early their growth, genomic proteomic fields implemented mechanisms assigning unique gene protein identifiers were essential organizing presentation enhancing bioinformatic approaches to extracting knowledge. Similar are currently absent from data. In order facilitate...

10.1093/glycob/cwx066 article EN Glycobiology 2017-07-07

Glycans are known as the third major class of biopolymers, next to DNA and proteins. They cover surfaces many cells, serving 'face' whereby other biomolecules viruses interact. The structure glycans, however, differs greatly from proteins in that they branched, opposed linear sequences amino acids or nucleotides. Therefore, storage glycan information databases, let alone their curation, has been a difficult problem. This caused duplicated efforts when integration is attempted between...

10.1093/nar/gkv1041 article EN cc-by-nc Nucleic Acids Research 2015-10-17

Abstract Glycans serve important roles in signaling events and cell-cell communication, they are recognized by lectins, viruses bacteria, playing a variety of many biological processes. However, there was no system to organize the plethora glycan-related data literature. Thus GlyTouCan (https://glytoucan.org) developed as international glycan repository, allowing researchers assign accession numbers glycans. This also aided integration across various databases. assigns glycans which defined...

10.1093/nar/gkaa947 article EN cc-by Nucleic Acids Research 2020-10-09

Accurate representation of structural ambiguity is important for storing carbohydrate structures containing varying levels in the literature and databases. Although many representations carbohydrates have been developed past, a generalized but discrete format did not exist. We had previously Web3 Unique Representation Carbohydrate Structures (WURCS) an attempt to define generalizable unique linear structures. However, it lacked sufficient rules uniquely describe ambiguous In this work, we...

10.1021/acs.jcim.6b00650 article EN cc-by Journal of Chemical Information and Modeling 2017-03-06

GlyTouCan version 1.0 was released in 2015 as the international glycan structure repository, and a new sequence format called WURCS (Web3 Unique Representation of Carbohydrate Structures) proposed during early stages project. uses its base representation for glycans because existing formats were insufficient their flexibility to represent any all universally. Therefore, order obtain strings or structures, conversion tools editors that can export became necessary. GlycanBuilder an obvious...

10.1016/j.carres.2017.04.015 article EN cc-by Carbohydrate Research 2017-04-19

We demonstrate high-definition, direct-printing of micron-scale metallic dots, comprised close-packed gold nanoparticles, by utilizing the optical vortex laser-induced forward transfer technique. observe that spin angular momentum vortex, associated with circular polarization, assists in close-packing nanoparticles within printed dots. The dots exhibit excellent electrical conductivity without any additional sintering processes. This technique applying to is an innovative approach metal...

10.1063/5.0187189 article EN cc-by APL Photonics 2024-03-01

<ns3:p>We report on the activities of 2015 edition BioHackathon, an annual event that brings together researchers and developers from around world to develop tools technologies promote reusability biological data. We discuss issues surrounding representation, publication, integration, mining reuse data metadata across a wide range biomedical types relevance for life sciences, including chemistry, genotypes phenotypes, orthology phylogeny, proteomics, genomics, glycomics, metabolomics....

10.12688/f1000research.18236.1 preprint EN cc-by F1000Research 2020-02-24

The effect of the properties photographic materials on preparation gold clusters in a gelatin layer using film was examined. cluster are formed by reducing gold(I)–thiocyanate complex solution latent image specks emulsion grains. Gold marked as non-linear optical material, and it necessary for this purpose to condense layer. This attempted two methods. first increase grains layer, second number grain. An ultrafine grain applied former, while high-intensity exposure chemically sensitized...

10.1179/136821904225011663 article EN The Imaging Science Journal 2004-09-01

ABSTRACT Glycomics targets released glycans from proteins, lipids and proteoglycans. High throughput glycomics is based on mass spectrometry (MS) that increasingly depends exchange of data with databases the use software. This requires an agreed format for accurately recording experiments, developing consistent storage modules granting public access to glycomic MS data. The introduction MIRAGE (Mimimum Requirement A Experiment) reporting standards was first step towards automating recording....

10.1101/401141 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2018-08-27

The Integrated Life Science Database Project of Japan funded a group glycoscientists to carry out project integrate glycoscience databases using Semantic Web technologies. As continuation the previous period, Consortium for Glycobiology and Glycotechnology (JCGGDB) developed several glycoscience-related databases. GlycoProtDB database is among those being integrated, providing an important resource understand protein glycosylation. Another integrated GlycoEpitope, comprehensive carbohydrate...

10.1016/j.pisc.2016.05.012 article EN cc-by Perspectives in Science 2016-10-20

10.1016/s0168-9002(01)01516-9 article EN Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2002-04-01

The dispersion of latent image specks (LISs) on reduction-sensitized octahedral grain (Oct) and cubic (Cub) emulsions that were exposed to light various intensity levels or a radiation was studied. number distribution LISs determined with arrested development gold deposition techniques. sensitized Oct sensitive extra-low-intensity (24 48 h) exposure. This exposure displayed narrow one-speck-per-grain pattern. changed broad for 1 s exposure, which obeyed the Poisson law at highest...

10.1080/13682199.2000.11784351 article EN The Imaging Science Journal 2000-01-01

The object of this research is to develop and evaluate the Online Abstract Paper Entry System (OAPES) that collects delivers medical academic meeting information online in Japan.CGI technology semi-automated program generation method are employed for OAPES software development accommodate various data collected by many meetings a common format achieve both flexibility efficiency.Using OAPES, an abstract, or paper, its related can be submitted via Internet. After contributions have been...

10.1055/s-0038-1625427 article EN Methods of Information in Medicine 2007-01-01
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