Gang Fu

ORCID: 0000-0003-2183-965X
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About
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Research Areas
  • Plant Pathogens and Fungal Diseases
  • Banana Cultivation and Research
  • Plant-Microbe Interactions and Immunity
  • Yeasts and Rust Fungi Studies
  • Plant Pathogenic Bacteria Studies
  • Plant Pathogens and Resistance
  • Machine Learning in Bioinformatics
  • Scientific Computing and Data Management
  • Semantic Web and Ontologies
  • Mycorrhizal Fungi and Plant Interactions
  • Computational Drug Discovery Methods
  • Research Data Management Practices
  • Gene expression and cancer classification
  • Plant tissue culture and regeneration
  • Bioinformatics and Genomic Networks
  • Crop Yield and Soil Fertility
  • Advanced Graph Neural Networks
  • Biomedical Text Mining and Ontologies
  • Fungal Plant Pathogen Control
  • Plant Disease Management Techniques
  • Medicinal Plants and Neuroprotection
  • Mycotoxins in Agriculture and Food
  • Chemical Synthesis and Analysis
  • Nematode management and characterization studies
  • Soil Carbon and Nitrogen Dynamics

Guangxi University
2007-2025

Ministry of Agriculture and Rural Affairs
2022-2025

Guangxi Academy of Agricultural Science
2013-2024

Institute of Plant Protection
2021-2022

Ruijin Hospital
2022

Shanghai Jiao Tong University
2022

National Center for Biotechnology Information
2015-2020

National Institutes of Health
2020

Yidu Central Hospital of Weifang
2020

Microsoft (United States)
2019

PubChem is an open repository for chemical structures, biological activities and biomedical annotations. Semantic Web technologies are emerging as increasingly important approach to distribute integrate scientific data. Exposing data services may help enable automated integration management, well facilitate interoperable web applications.This work, one of a series covering the PubChemRDF project, describes translate Substance Compound information into Resource Description Framework (RDF)...

10.1186/s13321-015-0084-4 article EN cc-by Journal of Cheminformatics 2015-07-13

Banana is the most popular and exported fruit also a major food crop for millions of people around world. Despite its importance, research into this limited hence, it suffers from disease threats. One those Panama or Fusarium wilt. In previous century wilt wiped out "Gros Michel" based banana industry in Central America. The epidemic was eventually quenched by planting "Cavendish" bananas. However, 50 years ago recurred, but now on Since then has spread across South-East Asia, to Middle-East...

10.3389/fpls.2018.00457 article EN cc-by Frontiers in Plant Science 2018-04-09

Bacillus subtilis B47 is an endophytic bacterium of tomato, and produces substance that strongly inhibits the growth Bipolaris maydis, pathogen southern corn leaf blight (SCLB), as well several other phytopathogenic fungi. The antifungal was purified from broth culture using acid precipitation, methanol extraction, three-step chromatography. Based on FT-IR spectrometry, amino composition, MALDI-TOF-MS/MS CID analyses, identified iturin A2, a cyclic lipopeptide antibiotic. To evaluate...

10.1016/s1671-2927(12)60786-x article EN cc-by-nc-nd Journal of Integrative Agriculture 2012-01-01

Representation learning provides new and powerful graph analytical approaches tools for the highly valued data science challenge of mining knowledge graphs. Since previous methods have mostly focused on homogeneous graphs, an important current is extending this methodology richly heterogeneous graphs domains. The biomedical sciences are such a domain, reflecting complexity biology, with entities as genes, proteins, drugs, diseases, phenotypes, relationships gene co-expression, biochemical...

10.1186/s12859-019-2914-2 article EN cc-by BMC Bioinformatics 2019-06-10

Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4) causes wilt of banana, the most devastating disease on a banana plant. The genome Foc TR4 encodes many candidate effector proteins. However, little is known about functions these proteins their contributions to development and virulence. Here, we discovered secreted metalloprotease, FocM35_1, which an essential virulence TR4. FocM35_1 was highly upregulated during early stages infection progress in bananas. knockout mutant...

10.3390/pathogens10060670 article EN cc-by Pathogens 2021-05-29

Melon (Cucumis melo L.) is an important economic crop in China, with a planting area of about 500,000 hectares, ranking first the world. In May 2024, anthracnose symptoms were found on melon plants, particularly severe mature fruits, Binyang County, Guangxi, China. Disease incidence was between 30% to 60% four surveyed areas. The fruits initially appeared as water-soaked lesions, gradually turning into dark brown sunken sometimes cracks. Additionally necrotic lesions yellowish edges leaves....

10.1094/pdis-11-24-2432-pdn article EN Plant Disease 2025-02-09

Pear (Pyrus pyrifolia) is an economically important fruit and widely planted in China. In September 2023, soft rot disease was observed on more than 20% of pear fruits (cv. Jinghua) a plantation approximately 1.0 ha Shilin County, Kunming City, Yunnan Province, The initial symptoms manifested as water-soaked lesions. Then, they rapidly expanded covered the whole fruit, which necrotic. At severe stage, infected turned brown dropped prematurely. To isolate identify causal pathogen, two...

10.1094/pdis-10-24-2204-pdn article EN Plant Disease 2025-03-03

Abstract Continuous cropping of bananas leads to Fusarium wilt, affecting crop health, yet employing biocontrol bacteria modulate rhizosphere microbial communities may offer effective disease suppression. This study revealed the secondary succession characteristics microbiota in banana fields after more than 5‐year continuous and assessed suppressive effects induced by strain Bacillus subtilis R31. Through high‐throughput sequencing, we observed a convergent enrichment core bacterial genera...

10.1002/imo2.70006 article EN cc-by iMetaOmics. 2025-03-18

Fusarium oxysporum f. sp. cubense (Foc) causes wilt, a devastating epidemic disease that has caused widespread damage to banana crops worldwide. We report the draft genomes of Foc race 1 (16117) and tropical 4 (Fusarium odoratissimum) (CNSD1) isolates from China, assembled using PacBio HiFi sequencing reads, with functional annotation performed. The strains group in distinct lineages within species complex. This genetic resource will contribute towards understanding pathogenicity...

10.20944/preprints202503.1789.v1 preprint EN 2025-03-25

In the context of drug discovery and development, much effort has been exerted to determine which conformers a given molecule are responsible for observed biological activity. this work we aimed predict bioactive using variant supervised learning, named multiple-instance learning. A single molecule, treated as bag conformers, is biologically active if only at least one its an instance, bioactivity; inactive none bioactivity. The implementation requires instance-based embedding, joint feature...

10.1186/1471-2105-13-s15-s3 article EN cc-by BMC Bioinformatics 2012-09-01

In drug discovery and development, it is crucial to determine which conformers (instances) of a given molecule are responsible for its observed biological activity at the same time recognize most representative subset features (molecular descriptors). Due experimental difficulty in obtaining bioactive conformers, computational approaches such as machine learning techniques much needed. Multiple Instance Learning (MIL) method capable tackling this type problem. MIL framework, each instance...

10.1186/1471-2105-14-s14-s16 article EN cc-by BMC Bioinformatics 2013-10-01

10.1016/j.physa.2018.02.142 article EN Physica A Statistical Mechanics and its Applications 2018-03-26

Banana wilt caused by Fusarium oxysporum f. sp. cubense has devastated a large number of banana plantations worldwide. Biological control is possible method to conquer this disease. However, the effect was often low and unstable while single biocontrol strain had been applied in field. Therefore, study aimed construct an effective compound microbial agent (FWB) In addition it, compounding strategy combining strains for improving investigated. Based on compatibility test, five representative...

10.3389/fmicb.2022.1066807 article EN cc-by Frontiers in Microbiology 2022-12-20

HomePlant DiseaseVol. 108, No. 3First Report of Bulb Rot Disease Banana Caused by Klebsiella variicola in China PreviousNext DISEASE NOTE OPENOpen Access licenseFirst ChinaShangbo Jiang, Di Yang, Chanjuan Du, Jin Zhang, Yunfeng Ye, Lianfu Pan, and Gang FuShangbo JiangPlant Protection Research Institute, Guangxi Academy Agricultural Sciences/Key Laboratory Green Prevention Control on Fruits Vegetables South Ministry Agriculture Rural Affairs/Guangxi Key Biology for Crop Diseases Insect Pests,...

10.1094/pdis-12-23-2693-pdn article EN Plant Disease 2024-02-05

There are a vast number of biology related research problems involving combination multiple sources data to achieve better understanding the underlying problems. It is important select and interpret most information from these sources. Thus it will be beneficial have good algorithm simultaneously extract rules features for interpretation predictive model. We propose an efficient algorithm, Combined Rule Extraction Feature Elimination (CRF), based on 1-norm regularized random forests. CRF...

10.1109/tnb.2012.2213264 article EN IEEE Transactions on NanoBioscience 2012-09-01

In February 2014, the National Library of Medicine formed Linked Data Infrastructure Working Group to investigate potential for publishing linked data, determine best practices and prioritize data projects, beginning with transforming Medical Subject Headings as a pilot. This article will review pilot project convert from XML RDF. It examine collaborative process, technical organizational issues tackled, future at library.

10.1080/19386389.2015.1099967 article EN Journal of Library Metadata 2015-10-02

Bacillus spp. is effective biocontrol agents for Fusarium wilt of banana (FWB), tropical race 4 (TR4). This study explores the colonization by subtilis , velezensis and amyloliquefaciens host plants elucidates mechanism antagonistic TR4 biocontrol. The authors selected one B. strain, three strains, strains that are proven to significantly inhibit in vitro optimized genetic transformation conditions explored their process plants. results showed we successfully constructed an fluorescent...

10.3389/fmicb.2021.754918 article EN cc-by Frontiers in Microbiology 2021-10-13

ECM33, a glycosylphosphatidylinositol (GPI)-anchored protein, is important for fungal development and infection through regulating cell wall integrity, however, the functions of its orthologs in pathogenesis have not been characterized Fusarium oxysporum. Here, we discovered GPI-anchored FocECM33, which required vegetative growth virulence Fusasium oxysporum f. sp. cubense tropical race 4 (Foc TR4). FocECM33 was highly upregulated during early process Foc TR4 banana roots. The targeted...

10.1016/j.funbio.2021.12.005 article EN cc-by-nc-nd Fungal Biology 2022-01-04

Fusarium wilt of banana (FWB), caused by oxysporum f. sp. cubense (Foc), is the most important constraint industry globally. In Nepal, epidemics resembling FWB have been increasingly observed on Malbhog cultivar in past several years. However, disease has not officially reported yet, and consequently, little known about pathogen present across country. this study, we characterized 13 fungal strains isolated from plants (Silk, AAB) showing symptoms similar to plantations Nepal. All were typed...

10.3390/jof9020208 article EN cc-by Journal of Fungi 2023-02-05

Abstract Glycogen synthase kinase‐3 (GSK‐3) is a multifunctional serine/threonine protein kinase which engaged in variety of signaling pathways, regulating wide range cellular processes. GSK‐3β, also known as tau I (TPK‐I), one the most important kinases implicated hyperphosphorylation that leads to neurodegenerative diseases. Hence, GSK‐3β has emerged an therapeutic target. To identify compounds are structurally novel and diverse compared previously reported ATP‐competitive inhibitors, we...

10.1002/minf.201400044 article EN Molecular Informatics 2014-09-01

Abstract Healthy, well‐rooted planting stocks are important for profitable fruit production of strawberry ( Fragaria × ananassa Duch.). Adequate nutrient inputs and crop‐rotation practices among the most measures to insure a successful, rapid development nursery plants. However, relationships between macronutrient use strawberry‐nursery‐plant formation in different rotation environments not well understood. Our objectives were assess plant P : N nutrition under various limited unlimited...

10.1002/jpln.201200654 article EN Journal of Plant Nutrition and Soil Science 2014-02-11
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