A5083249439- Parasitic Infections and Diagnostics
- Tuberculosis Research and Epidemiology
- Natural product bioactivities and synthesis
- Bee Products Chemical Analysis
- Mycobacterium research and diagnosis
- Essential Oils and Antimicrobial Activity
- Insect and Pesticide Research
- Phytochemistry and Biological Activities
- vaccines and immunoinformatics approaches
- Phytochemical Studies and Bioactivities
- Amoebic Infections and Treatments
- Phytochemistry and Bioactive Compounds
- Immunodeficiency and Autoimmune Disorders
- Immunotherapy and Immune Responses
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Bioactive natural compounds
- Trace Elements in Health
- Ethnobotanical and Medicinal Plants Studies
- Healthcare and Venom Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Viral gastroenteritis research and epidemiology
- Toxin Mechanisms and Immunotoxins
- Immune Cell Function and Interaction
Universidad de Las Américas
2024
Universidad de Sonora
2014-2023
Universidad de Hermosillo
2012-2022
Instituto de Química y Fisicoquímica Biológicas
2016
El Colegio de Sonora
2016
Centro de Investigación en Alimentación y Desarrollo
2016
Centers for Disease Control and Prevention
2016
Instituto Politécnico Nacional
2003-2004
Hospital General Dr. Manuel Gea Gonzalez
2004
Mexican Social Security Institute
2004
Abstract Background The aim of this study, is to investigate the in vitro antioxidant activity, total phenols content, flavonoids content and antiproliferative activity methanolic extracts plants: Krameria erecta , Struthanthus palmeri Phoradendron californicum Senna covesii Stegnosperma halimifolium used by different ethnic groups from northwestern Mexico treatment cure various diseases. Methods was measured 2,2-diphenyl-1-picrylhydrazyl (DPPH) Ferric Reducing/Antioxidant Power assay...
Biological properties of Sonoran propolis (SP) are influenced by harvest time. Caborca showed cellular protective capacity against reactive oxygen species, which might be implicated in anti-inflammatory effects. However, the activity SP has not been investigated so far. This study previously characterized seasonal extracts (SPE) and some their main constituents (SPC). The SPE SPC was evaluated measuring nitric oxide (NO) production, protein denaturation inhibition, heat-induced hemolysis...
Chagas disease is a neglected caused by the parasite Trypanosoma cruzi, public health problem in both endemic and non-endemic countries. In Mexico, southern region considered endemic, cases are frequently reported; however, northwestern region, only few confirmed annually. This study describes, for first time, Discrete Typing Unit (DTU) of cruzi volunteer blood donor rejected being reactive Mexico. Seroreactivity was using “in-house” ELISAs which employed three different antigens: total...
Helicobacter pylori is the major etiologic agent of such gastric disorders as chronic active gastritis and carcinoma. Over past few years, appearance antibiotic-resistant bacteria has led to development better treatments, use natural products. This study evaluated anti-H. activity 17 Mexican plants used mainly in northwestern part Mexico (Sonora) for empirical treatment gastrointestinal disorders. The methanolic extracts was determined by using broth microdilution method. 50% minimum...
Cryptosporidiosis is a parasitic disease caused by Cryptosporidium spp. In immunocompetent individuals, it usually causes an acute and self-limited diarrhea; in infants, infection with can cause malnutrition growth retardation, declined cognitive ability. this study, we described for the first time distribution of C. parvum hominis subtypes 12 children Mexico sequence characterization 60-kDa glycoprotein (GP60) gene Cryptosporidium. Altogether, 7 belonging to 4 subtype families (Ia, Ib, Id...
Infectious diseases have consistently served as pivotal influences on numerous civilizations, inducing morbidity, mortality, and consequently redirecting the course of history. Their impact extends far beyond acute phase, characterized by majority symptom presentations, to a multitude adverse events sequelae that follow viral, parasitic, fungal, or bacterial infections. In this context, myriad related various infectious been identified, spanning short long-term durations. Although these are...
We report the synthesis of hollow Au–Ag bimetallic nanoparticles with high photothermal stability under NIR irradiation.
Propolis is a cereus resin with complex chemical composition that possesses wide range of biological activities. The aim this study was to evaluate the <i>in vitro</i> anti-<i>Giardia lamblia</i> activity Sonoran propolis collected from three different areas Desert in northwestern Mexico (Caborca, Pueblo de Alamos, and Ures) some its constituents. Additionally, we also analyzed seasonal effect on anti-<i>G. propolis. <i>G. trophozoite cultures were treated concentrations or compounds during...
In Mexico about 4,000 plant species have some medicinal use. The aim of this work was to evaluate the antimicrobial activity six Mexican plants against fungi and Gram-positive Gram-negative bacteria. Methanolic extracts were prepared from Amphypteringium adstrigens, Castella tortuosa, Coutarea latiflora, Ibervillea sonorae, Jatropha cuneata, Selaginella lepidophylla. antibacterial antifungal activities determined by broth microdilution method radial growth inhibition assay, respectively. All...
Cancer is one of the leading causes death worldwide. Natural products have been regarded as important sources potential chemotherapeutic agents. In this study, we evaluated anti-proliferative activity Argemone gracilenta's methanol extract and its fractions. We identified those compounds most active fractions that displayed activity.The on different cancerous cell lines (M12.C3F6, RAW 264.7, HeLa) was in vitro using MTT colorimetric method. Identification present with highest achieved by...
Abstract Background Sonoran ethnic groups (Yaquis, Mayos, Seris, Guarijíos, Pimas, Kikapúes and Pápagos) use mainly herbal based preparations as their first line of medicinal treatment. Among the plants used are those with anti-tuberculosis properties; however, no formal research is available. Methods Organic extracts were obtained from nine traditionally by to treat different kinds diseases; three them tuberculosis. All tested against Mycobacterium tuberculosis H37Rv using Alamar Blue redox...
Context: Tuberculosis is primarily caused by Mycobacterium tuberculosis (Mtb). Previous studies have shown that the dichloromethanic extract of Ambrosia confertiflora DC (Asteraceae) inhibited Mtb.Objective: To isolate compounds responsible for mycobactericidal activity against clinical Mtb strains.Materials and methods: The aerial parts A. was separated using chromatography columns. Mycobactericidal isolated evaluated Alamar Blue bioassay (128–16 μg/mL, 7 days). Cytotoxicity tested normal...
Breast cancer mortality rates in Latin America (LA) are higher than those the United States, possibly because of advanced disease presentation, health care disparities, or unfavorable molecular subtypes. The American Cancer Research Network was established to address these challenges and promote collaborative clinical research. Molecular Profiling Study (MPBCS) aimed evaluate characteristics treatment outcomes LA participants with locally breast (LABC).
The cellular immune response plays a critical role in the containment of persistent Mycobacterium tuberculosis infection; however, immunological mechanisms that lead to its control are not completely identified. goal this study was evaluate B (CD19+) and T (CD3+) peripheral blood lymphocyte profiles T-cell subsets (CD4+ CD8+) patients with pulmonary (TB). Percentages (p = 0.02) absolute numbers 0.005) cells were significantly lower TB than healthy donors. In contrast, percentages 0.12) 0.14)...
Asclepias subulata Decne. (Apocynaceae) is a shrub used in the Mexican traditional medicine for treatment of cancer.The objective this study was to evaluate antiproliferative activity methanol extract aerial parts A. and its fractions against different cancer cell lines. Additionally, we analyzed mechanism action active fractions.Methanol were prepared by serial extraction with n-hexane, ethyl acetate, ethanol. The evaluated, several murine (M12.C3.F6, RAW 264.7, L929) human (HeLa, A549,...
Vibrio parahaemolyticus ( Vp ), a typical microorganism inhabiting marine ecosystems, uses pathogenic virulence molecules such as hemolysins to cause bacterial infections of both human and animals. The thermolabile hemolysin TLH lyses erythrocytes by phospholipase B/A2 enzymatic activity in egg-yolk lecithin. However, few studies have been characterized the biochemical properties use molecular target for natural compounds an alternative control infection. Here, we evaluated inhibition...