- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Acute Ischemic Stroke Management
- Hip and Femur Fractures
- Cardiac Arrhythmias and Treatments
- Emergency and Acute Care Studies
- Cerebrovascular and Carotid Artery Diseases
- Organ Transplantation Techniques and Outcomes
- Lipoproteins and Cardiovascular Health
- Advanced battery technologies research
- Aortic aneurysm repair treatments
- Pelvic and Acetabular Injuries
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Chronic Disease Management Strategies
- Pituitary Gland Disorders and Treatments
- Health Promotion and Cardiovascular Prevention
- Advanced Battery Technologies Research
- Hemodynamic Monitoring and Therapy
Aarhus University Hospital
2015-2024
Aarhus University
1993-2022
Aalborg University Hospital
2010-2018
Vetenskap I Skolan
2018
University of Copenhagen
1993-2018
University of Southern Denmark
2018
Rigshospitalet
2018
University of Alberta
2002-2017
Odense University Hospital
2012-2016
Danish Diabetes Academy
2016
Background Quantitative flow ratio ( QFR ) is a novel modality for physiological lesion assessment based on 3‐dimensional vessel reconstructions and contrast velocity estimates. We evaluated the value of online during routine invasive coronary angiography procedural feasibility, diagnostic performance, agreement with pressure‐wire–derived fractional reserve FFR as gold standard in an international multicenter study. Methods Results FAVOR II E‐J (Functional Assessment by Various Flow...
BackgroundRemote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown reduce myocardial infarct size in patients ST-elevation infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote could incidence of cardiac death hospitalisation for heart failure at 12 months.MethodsWe did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) 33...
Abstract Objective To investigate the association between SARS-CoV-2 vaccination and myocarditis or myopericarditis. Design Population based cohort study. Setting Denmark. Participants 4 931 775 individuals aged 12 years older, followed from 1 October 2020 to 5 2021. Main outcome measures The primary outcome, myopericarditis, was defined as a combination of hospital diagnosis pericarditis, increased troponin levels, stay lasting more than 24 hours. Follow-up time before compared with...
Background— Among drug-eluting stents released to date, the sirolimus-eluting stent has demonstrated least amount of late lumen loss, but its efficacy and safety have not been compared head-to-head with next-generation everolimus-eluting stent. Methods Results— The Scandinavian Organization for Randomized Trials Clinical Outcome IV (SORT OUT IV) trial was a randomized multicenter, single-blind, all-comer, 2-arm, noninferiority comparing in patients coronary artery disease. primary end point...
Coronary drug-eluting stents with biodegradable polymers have been designed to improve safety and efficacy.The Scandinavian Organization for Randomized Trials With Clinical Outcome (SORT OUT) VII trial-a large-scale registry-based randomized, multicenter, single-blind, 2-arm, noninferiority trial-compared 2 polymer stents: the thin-strut cobalt-chromium sirolimus-eluting Orsiro stent stainless steel biolimus-eluting Nobori in an all-comer patient population. The primary end point target...
Background: Pneumonia may be a major contributor to hospitalizations for chronic obstructive pulmonary disease (COPD) exacerbation and influence their outcomes. Methods: We examined hospitalization rates, health resource utilization, 30-day mortality, risk of subsequent COPD exacerbations with without pneumonia in Denmark during 2006–2012. Results: identified 179,759 exacerbations, including 52,520 first-time (29.2%). was frequent (36.1%), but declined successive 25.6% by the seventh or...
Percutaneous coronary intervention in complex bifurcation lesions is prone to suboptimal implantation results and associated with increased risk of subsequent clinical events. Angiographic ambiguity high during stenting, but it unknown if procedural guidance by intravascular optical coherence tomography (OCT) improves outcome. OCTOBER a randomized, investigator-initiated, multicenter trial aimed show superiority OCT-guided stent compared standard angiographic-guided lesions. The primary...
Background and Purpose— Recent studies indicate a possible beneficial effect on neuroregeneration vascular protection of selective serotonin reuptake inhibitors after stroke. We conducted national multicentre study to explore these effects. Methods— The TALOS (The Efficacy Citalopram Treatment in Acute Stroke) is Danish placebo-controlled, randomized, double-blind citalopram started within 7 days symptom onset detect improvement functional outcomes cardiovascular nondepressed, first-ever...
Background and Purpose- Diabetes mellitus (DM) non-DM patients without coronary artery disease (CAD) have a similar low risk of myocardial infarction after angiography. The ischemic stroke in DM dependent on CAD status is less explored. We examined whether to that with neither nor CAD. Methods- conducted cohort study who underwent angiography between 2004 2012 Western Denmark. Patients diagnosed previous or transient attack were excluded. stratified according the presence Follow-up started...
OBJECTIVE The risk of myocardial infarction (MI) in patients with diabetes is greater than for without diabetes. Consequently, prophylactic treatment recommended and factors ischemic heart disease. We aimed to estimate the adverse cardiac events coronary artery disease (CAD) after angiography (CAG). RESEARCH DESIGN AND METHODS A population-based cohort registered Western Denmark Heart Registry who underwent CAG between 1 January 2003 31 December 2012 was stratified according presence or...
Stent thrombosis is a serious complication of percutaneous coronary intervention (PCI). We examined the incidence stent and other outcomes in patients treated with PCI paclitaxeleluting stents (PES), sirolimus-eluting (SES) or bare-metal (BMS).