A5106942460- Adipose Tissue and Metabolism
- Stress Responses and Cortisol
- Fatty Acid Research and Health
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Antioxidant Activity and Oxidative Stress
- Liver Disease Diagnosis and Treatment
- Cholesterol and Lipid Metabolism
- Urinary Bladder and Prostate Research
- Nutritional Studies and Diet
- Neuroendocrine regulation and behavior
- Adrenal Hormones and Disorders
- Edible Oils Quality and Analysis
- Metabolomics and Mass Spectrometry Studies
- Peroxisome Proliferator-Activated Receptors
- Muscle metabolism and nutrition
- Lipid metabolism and biosynthesis
- Pelvic floor disorders treatments
- Neuroscience and Neuropharmacology Research
- Nanoparticles: synthesis and applications
- Phytochemicals and Antioxidant Activities
- Paraoxonase enzyme and polymorphisms
- Exercise and Physiological Responses
- Cannabis and Cannabinoid Research
- Heavy Metal Exposure and Toxicity
Dynamique Musculaire et Métabolisme
2016-2023
Physiologie de la Nutrition et du Comportement Alimentaire
2013-2023
Université de Montpellier
2004-2021
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2021
Institut de Recherche pour le Développement
2012-2020
Hôpital de la Conception
2018-2020
Aix-Marseille Université
2016-2019
Institut National de la Recherche Agronomique
2019
John Wiley & Sons (United Kingdom)
2017
Institut Agro Montpellier
2012-2015
Understanding the mechanisms involved in biogenesis of N-arachidonoylethanolamine (anandamide) and N-palmitoylethanolamine is important view possible role these lipids as endogenous cannabinoid substances. Anandamide (which activates CB1 receptors) a CB2-like receptor subtype mast cells) may both derive from cleavage precursor phospholipid, N-acylphosphatidylethanolamine (NAPE), catalyzed by Ca(2+)-activated D-type phosphodiesterase activity. We report here that de novo biosynthesis NAPE...
The bioavailability in rats orally treated with silver nanoparticles is studied through the analysis of their content liver, kidney, feces and urine.
Inflammation and oxidative stress are thought to be involved in, or associated with, the development of obesity, dyslipidemia, hepatic steatosis, insulin resistance. This work was designed determine evolution inflammation during onset progression steatosis glucose intolerance. Seventy-five male Wistar rats were divided control high-fat high-fructose (HFHFr) groups. A subgroup each group sacrificed at 4, 8, 12, 16, 20 weeks. HFHFr-fed exhibited overweight, intolerance, with increased contents...
The effects of various stressors (restraint, ether, histamine and insulin-induced hypoglycemia stress) on the early time course activation different catecholaminergic (CA) cell groups A1/C1, A2/C2 locus ceruleus (LC) from brainstem were studied. activity central noradrenergic neurons was assessed by measuring in tissue punches 3,4-dihydroxyphenylacetic acid (DOPAC) level, a side metabolite noradrenaline (NA) adrenaline biosynthesis that is thought to reflect NA cells. Short 5 min restraint...
This study explored plasma levels and urinary fecal excretion of metabolites microbial-derived catabolites over a 24 h period following the ingestion red wine (RWP) or grape seed (GSP) proanthocyanidin-rich extracts by rats.
We evaluated the effect of intake a grapevine-shoot phenolic extract (Vineatrol 30) on early atherosclerosis in hamsters fed hyperlipidic diet. Golden Syrian received for 13 weeks either standard diet, high-fat (HF) or HF diet plus Vineatrol 30 at 0.04, 0.2, 1.0 mg/(kg body weight/d). measured plasma lipids and glucose, insulin, leptin adiponectin, as well liver TNF-α IL-6 levels. Oxidative stress was assessed by measuring paraoxonase activity (PON) superoxide anion production (O(2)(•-))....
Abstract The incidence of obesity and its metabolic complications are rapidly increasing become a major public health issue. This trend is associated with an increase in the prevalence non-alcoholic fatty liver disease (NAFLD), insulin resistance diabetes. sequence events leading to NAFLD progression mitochondrial dysfunction their interrelation remains be elucidated. study aimed explore installation association structure activity changes rats fed obesogenic diet up 20 weeks. Male Wistar...
Workout capacity is energy-production driven. To produce peak metabolic power outputs, the organism predominantly relies more on anaerobic metabolism, but this undoubtedly has a negative and limiting impact muscle function performance. The aim of study was to evaluate if an innovative polyphenol-based food supplement, PerfLoad®, able improve homeostasis physical performance during high-intensity exercises under conditions. effect supplementation been investigated fifteen...
Stereotaxic deletion of selected areas the ventral noradrenergic ascending bundle (VNAB-X) by discrete bilateral injections 6-hydroxydopamine (6-OHDA; 4 µg in 0.2 µl saline) was used to explore role brain catechol-amines (CA) and their interaction with corticosteroid feedback stress responses ACTH-corticosterone (CORT) axis. The stereotaxic coordinates for 6-OHDA lesions optimization postlesion delays were determined (a) radioautographic labeling VNAB axons after tracer into dorsal A2/C2, or...
This study explored major systems of reactive oxygen species (ROS) production and their consequences on oxidative stress, mitochondriogenesis muscle metabolism in aged rats, evaluated the efficiency 30-day oral supplementation with a moderate dose red grape polyphenol extract (RGPE) these parameters. In liver NADPH oxidase activity was increased mitochondrial respiratory chain complex activities were altered, while xanthine remained unchanged. muscles, only modified aging. The intake RGPE...
Scope High-fat (HF) diets contribute to the development of cardiovascular diseases and metabolic syndrome. This study was undertaken investigate beneficial effects Vineatrol®-enriched red wines on blood lipids, oxidative stress inflammation, role some pathway regulatory proteins. Methods results Golden Syrian hamsters received an HF diet for 13 wk, in presence or absence supplemented with Vineatrol® (RWV) not. The increased plasma cholesterol, triglycerides, glucose, insulin, which were...
Overweight and obesity adversely affect health-related quality of life (HRQOL) through day-to-day impairments both mental physical functioning. It is assumed that polyphenols within the Mediterranean diet may contribute to improving HRQOL. This investigation aimed at studying effects a polyphenol-rich ingredient on HRQOL in overweight obese but otherwise healthy individuals. A randomized, double-blind, placebo-controlled study including 72 volunteers was conducted. Subjects were randomly...
High‐intensity exercises are known to provoke delayed onset muscle soreness (DOMS). Delayed typically occurs within the first 24 h, peaks between and 72 can last as long 5–7 days post‐exercise. is a multifactorial process involving both mechanical biochemical components, associated with clinical features that may limit range of motion, athletes seek for effective recovery strategies optimize future training sessions. TensLess ® food supplement developed help manage post‐exercise recovery....
A number of recent studies have suggested that interleukin-1β (IL-1β) is a major mediator contributing to the recruitment hypothalamo-pituitary-adrenal (HPA) axis following infectious aggressions. Central catecholamines modulate response HPA axis. To investigate importance afferent catecholaminergic pathways in pathophysiological situation, we used intraperitoneal (i.p.) IL-1β injection (mimicking peripheral infections) and investigated effects on responses bilateral neurotoxic (6-OHDA)...