- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Advanced Neuroimaging Techniques and Applications
- Pharmacological Effects and Toxicity Studies
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- RNA regulation and disease
- Advanced MRI Techniques and Applications
- Vestibular and auditory disorders
- Tensor decomposition and applications
- Influenza Virus Research Studies
- Biochemical effects in animals
- FinTech, Crowdfunding, Digital Finance
- Cancer Diagnosis and Treatment
- Language Development and Disorders
- Cancer and Skin Lesions
- Sustainable Finance and Green Bonds
- Neurobiology of Language and Bilingualism
- Traditional Chinese Medicine Studies
- Hedgehog Signaling Pathway Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Neuroscience and Neural Engineering
- Diagnosis and treatment of tuberculosis
- Uterine Myomas and Treatments
First Affiliated Hospital of Guangzhou Medical University
2024
Guangzhou Medical University
2024
Capital Medical University
2009-2023
Beijing Friendship Hospital
2022
Beijing Chao-Yang Hospital
2015-2020
Beijing Institute of Neurosurgery
2014
Objective: We propose an improved automated high frequency oscillations (HFOs) detector that could not only be applied to various intracranial electrodes, but also automatically remove false HFOs caused by high-pass filtering. proposed a continuous resection ratio of order HFO channels and compared this with each patient's post-surgical outcomes determine the quantitative threshold distribution delineate epileptogenic zone (EZ). Methods: enrolled total 43 refractory epilepsy patients. They...
This study investigated the texture features and volumes of bilateral hippocampus medial temporal lobe (MTL) in magnetic resonance imaging (MRI) patients with Alzheimer's disease (AD). Texture were extracted using gray level co-occurrence matrix (GLCM) 29 elderly AD patients, 19 age-matched non-demented controls (EC) 18 young healthy (YC). The correlation between corresponding was analyzed. Significant differences found both HF MTL EC group (p<;0.001) (p<;0.01). In addition, markedly...
Objective: To investigate the differences of texture features among macroscopic lesion white matter (LWM), normal appearing (NAWM) in magnetic resonance images (MRI) from patients with multiple sclerosis (MS) and (NWM) controls by gray-level difference statistics, to detect hidden abnormality NAWM. Methods: T2-weighted MRI 26 MS healthy subjects were selected, regions interests (ROI) chosen patient subject for LWM, NAWM NWM respectively. All ROI analyzed contrast, angular second moment, mean...
Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse parameters for terminating cortical electrical stimulation-induced remain unclear. In present study, we examined effects of different brief-pulse frequencies (5, and 100 Hz) on 10 patients with refractory epilepsy. Results demonstrated that could conclusion, (1) a was more effective when afterdischarge did not extend surrounding brain area. (2) A higher...
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which leads to focal plaques demyelination and axonal impairment in system. occurred brain tissue, optic nerve spinal cord, mainly severe progressive neurological dysfunction, such as blindness, paralysis death. There are about 65,000 patients with MS China, recently incidence rate increasing, most familiar factor for non-traumatic deformity third or fourth decade life. In this paper, regions interesting...
In the 21st century, technology and financial innovation are inseparable. The industry is undergoing a new change: Internet, "green digital finance" which follows pace of world's also beginning to appear in front public.
Abstract Background Surgical treatment for patients with adult-onset Rasmussen’s encephalitis (A-RE) is rarely reported. We investigated the clinical and surgical features of two A-RE who underwent functional hemispherectomy. Case presentation The data manifestations, neuroimaging, outcomes was reviewed. initially presented recurrent partial seizures or secondly generalized tonic clonic seizures. Gradually, showed unilateral limb paralysis as well chronic focal epileptic status. Both...
Accurate localization of brain regions responsible for language and cognitive functions in epilepsy patients is important. Electrocorticography (ECoG)-based real-time functional mapping (RTFM) has been shown to be a safer alternative electrical cortical stimulation (ESM), which currently the clinical/gold standard. Conventional methods analyzing RTFM data mostly account ECoG signal certain frequency bands, especially high gamma. Compared ESM, they have limited accuracy when assessing channel...
Objective: To evaluatethe clinical efficacy and complications of skin graft flap plastic technique covered the defect in perineal Paget's disease postoperatively. Methods: The study comprised 6 patients diagnosed with at Beijing Chao-Yang Hospital from June 2017 to July 2019, all available data reviewed. defects after resection lesions were reconstructed graft, advancement during operation, respectively. operation time, or survival situation, intraoperative postoperative recorded. Results:...
Objective To describe the characteristics of electroclinical manifestations in patients with hypermotor seizures (HMSs) originating from temporal lobe. Methods The data 12 who had HMSs origin and underwent surgical treatment April 2001 to February 2015 Beijing Institute Functional Neurosurgery were retrospectively reviewed, including seizure histories, imaging reports, video-electroencephalogram (EEG) monitoring, operative records pathological findings. Results Ten reported...
Objective To investigate the knowledge and recognition of middle aged elderly cognitive normal people in clock drawing test (CDT) determine items CDT. Methods Two hundred sixty four from community were involved cross-sectional study. The questionnaire was comprised 26 scoring CDT literature. Each item rated by subjects as complete agreement, partial agreement or disagreement. Pearson correlation analysis used to analyze related age education degree. Results There 5 significantly...
Objective To summarize the epileptogenic localizations, pathological findings and long-term surgical outcomes of patients with refractory epilepsy at a single center during past 15 years. Methods A total 2 424 who underwent surgeries Department Functional Neurosurgery between April 2001 December 2016 were included in this retrospective study. The traits localization analyzed. Outcomes all followed up longer than 1 year post studied two stages, rate seizure free was...
Objective: To investigate the clinicopathological features of angioimmunoblastic T-cell lymphoma pattern Ⅰ (AITL Pattern Ⅰ). Methods: The data 11 AITL cases that were diagnosed at Beijing Friendship Hospital Affiliated to Capital Medical University (10 cases) and Lu Daopei (1 from January 2019 October 2021 retrospectively collected. Immunophenotype, Epstein-Barr virus infection status T cell receptor (TCR) clonality tumor cells tested, analyzed. Results: Among cases, male female ratio was...