A5068005983- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Vestibular and auditory disorders
- Climate Change and Health Impacts
- Biochemical Analysis and Sensing Techniques
- Health disparities and outcomes
- Global Public Health Policies and Epidemiology
- Hearing, Cochlea, Tinnitus, Genetics
- Viral Infections and Vectors
- Olfactory and Sensory Function Studies
- Neurobiology and Insect Physiology Research
- Neural dynamics and brain function
- Global Health Care Issues
- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- Global Health and Epidemiology
- Animal Disease Management and Epidemiology
- Neuroscience of respiration and sleep
- Virology and Viral Diseases
- Neonatal and fetal brain pathology
- Vector-borne infectious diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Healthcare Systems and Reforms
- COVID-19 and healthcare impacts
Dartmouth College
2015-2024
Institute for Health Metrics and Evaluation
2024
University of Washington
2024
Deakin University
2023
Marine Biological Laboratory
2018
University of New Hampshire
2015
<h2>Summary</h2><h3>Background</h3> Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from Global Burden of Disease, Injuries, Risk Factor Study estimated burden 15 neurological conditions in 2015 2016, but these analyses did not defined by International Classification Diseases (ICD)-11, or a subset cases congenital,...
A comprehensive understanding of temporal trends in the disease burden Australia is lacking, and these are required to inform health service planning improve population health. We explored diseases their risk factors from 1990 2019 through a analysis Global Burden Disease Study (GBD) 2019.In this systematic for GBD 2019, we estimated all-cause mortality using standardised methodology. Data sources included primarily vital registration systems with additional data sample registrations,...
BackgroundBangladesh has made substantial progress in improving socioeconomic and health indicators over the past 50 years, but data on national disease burden are scarce. We used from Global Burden of Diseases, Injuries, Risk Factors Study (GBD) 2019 to estimate diseases risk factors Bangladesh 1990 2019.MethodsFor this systematic analysis, we analysed vital registration systems, surveys, censuses using multistage modelling processes life expectancy at birth, mortality rate, years lost...
The restrosplenial cortex (RSC) has a well-established role in contextual and spatial learning memory, consistent with its known connectivity visuo-spatial association areas. In contrast, RSC appears to have little involvement delay fear conditioning an auditory cue. However, all previous studies examined the contribution of recently acquired memories. Since neocortical regions been implicated permanent storage remote memories, we remotely Experiment 1, retrieval memory was impaired when...
South Korea has one of the longest operating universal health coverage (UHC) systems. A comprehensive analysis long-term trajectories morbidity and mortality in Korean population after inception UHC is needed to inform health-care policy practice.We used data from Global Burden Disease Study (GBD) 2019 present estimates cause-specific mortality, incidence, prevalence, years life lost (YLLs), lived with disability, disability-adjusted life-years (DALYs) 1990 2019. We also examined forecasted...
Abstract Head direction (HD) cells, which fire persistently when an animal's head is pointed in a particular direction, are widely thought to underlie sense of spatial orientation and have been identified several limbic brain regions. Robust HD cell firing observed throughout the thalamo‐parahippocampal system, although recent studies report that parahippocampal cells exhibit distinct properties, including conjunctive aspects with other parameters, suggest they play specialized role...
Head direction (HD) cells fire as a function of the animal’s directional heading and provide animal with sense direction. In rodents, these neurons are located primarily within limbic system, but small populations HD found in two extralimbic areas: medial precentral cortex (PrCM) dorsal striatum (DS). cell activity structures could be driven by output from circuit or generated intrinsically. We examined possibilities recording PrCM DS control rats anterodorsal thalamic nucleus (ADN) lesions,...
Head direction (HD) cells, which fire action potentials whenever an animal points its head in a particular direction, are thought to subserve the animal's sense of spatial orientation. HD cells found prominently several thalamo-cortical regions including anterior thalamic nuclei, postsubiculum, medial entorhinal cortex, parasubiculum, and parietal cortex. While number methods neural decoding have been developed assess dynamics signals within regions, studies conducting quantitative...
In mammals, a complex array of oral sensors assess the taste, temperature and haptic properties food. Although representation taste has been extensively studied in gustatory cortex, it is unclear how somatosensory cortex encodes information about stimuli. Moreover, poorly understood different sensory modalities are integrated responses translated into motor actions. To investigate whether processes food-related sensations movements, we performed vivo whole-cell recordings mapping experiments...
An animal’s directional heading within its environment is encoded by the activity of head direction (HD) cells. In rodents, these neurons are found primarily limbic system in interconnected structures that form HD circuit. our accompanying report this issue, we describe two cell populations located outside circuit medial precentral cortex (PrCM) and dorsal striatum (DS). These extralimbic areas receive their signals from but do not provide critical input or feedback to cells (Mehlman ML,...
In a seminal paper in the cognitive sciences, Chun and Jiang (1998) described contextual cueing paradigm which they used artificial stimuli showed that people became faster to locate target when background predicted location of compared it did not. Here we examined pigeons for first time using procedures similar those Jiang. test, had search among display seven distractors; during one condition, position distractors target, second there was no relationship between two. presented with...
Specialized circuitry in the brain processes spatial information to provide a sense of direction used for navigation. The dorsal tegmental nucleus (DTN) is core component this and utilizes vestibular inputs generate neural activity encoding animal's directional heading. Projections arising from prepositus hypoglossi (NPH) medial (MVe) are thought transmit critical signals DTN other areas, including abducens (ABN), eye movement circuitry. Here, we utilized dual retrograde tracer approach rats...