- Korean Peninsula Historical and Political Studies
- Health disparities and outcomes
- Global Health Care Issues
- Climate Change and Health Impacts
- Suicide and Self-Harm Studies
- Global Public Health Policies and Epidemiology
- Schizophrenia research and treatment
- Health and Wellbeing Research
- Global Cancer Incidence and Screening
- Attention Deficit Hyperactivity Disorder
- Health Systems, Economic Evaluations, Quality of Life
- Child Nutrition and Water Access
- Healthcare Systems and Reforms
- Global Maternal and Child Health
- Orthopedic Surgery and Rehabilitation
- COVID-19 and healthcare impacts
- Musculoskeletal pain and rehabilitation
- Injury Epidemiology and Prevention
- Bipolar Disorder and Treatment
- Acute Ischemic Stroke Management
- Diverse Approaches in Healthcare and Education Studies
- Smoking Behavior and Cessation
- Cardiac, Anesthesia and Surgical Outcomes
- Korean Urban and Social Studies
- Trauma and Emergency Care Studies
Korea University
2011-2025
Yonsei University
2009-2025
Electronics and Telecommunications Research Institute
2019-2025
The University of Sydney
2023-2024
Chonnam National University Hospital
2005-2024
Northern Sydney Local Health District
2024
Institute for Health Metrics and Evaluation
2021-2024
University of Washington
2021-2024
Institute for Musculoskeletal Health
2023-2024
Wenzhou Medical University
2024
Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death disability due to musculoskeletal disorders, Global Burden of Diseases, Injuries, Risk Factors Study (GBD) includes a residual category for other osteoarthritis, rheumatoid arthritis, gout, low back pain, neck pain. This is called includes, example, systemic lupus erythematosus spondylopathies. We provide updated...
Abstract Objectives This study aimed to examine changes in life expectancy (LE), health-adjusted (HALE), unhealthy years of life, and disease burden older people industrialised countries associations with health systems. Methods We used estimates LE HALE, loss (YLL), lived disability (YLD) for individuals aged 70 over 33 from 1990 2019 the Global Burden Disease Study 2019. A linear regression analysis was conducted association outcomes Healthcare Access Quality (HAQ) index. Results HALE...
Abstract α-Fetoprotein (AFP) is a self protein expressed by fetal liver at high levels, but transcriptionally repressed birth. AFP up-regulated in hepatocellular carcinomas, and patients with active disease could have plasma levels as 1 mg/mL. We previously identified four immunodominant HLA-A*0201-restricted peptides [hAFP137-145 (PLFQVPEPV), hAFP158-166 (FMNKFIYEI), hAFP325-334 (GLSPNLNRFL), hAFP542-550 (GVALQTMKQ)] derived from human that stimulate specific T cell responses healthy donor...
Meningiomas are one of the most common adult brain tumors. For patients, surgical excision is curative. However, up to 20% recur. Currently, molecular determinants predicting recurrence and malignant transformation lacking. We performed retrospective global genetic genomic analysis 85 meningioma samples various grades. Copy number alterations were assessed by 100K single-nucleotide polymorphism arrays correlated with gene expression, proliferation indices clinical outcome. In addition...
Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif (TAZ) identified as effector protein differentiation. However, detailed underlying mechanism regarding role TAZ in not yet fully understood. In this report, we showed that regulates fate ERK or JNK...
South Korea has one of the longest operating universal health coverage (UHC) systems. A comprehensive analysis long-term trajectories morbidity and mortality in Korean population after inception UHC is needed to inform health-care policy practice.We used data from Global Burden Disease Study (GBD) 2019 present estimates cause-specific mortality, incidence, prevalence, years life lost (YLLs), lived with disability, disability-adjusted life-years (DALYs) 1990 2019. We also examined forecasted...
Understanding the magnitude of economic impact an illness on society is fundamental to planning and implementing relevant policies. South Korea operates a compulsory universal health insurance system providing favorable conditions for evaluating nationwide burden illnesses. The aim this study was estimate costs asthma imposed Korean society. National Health Insurance claims database used determining care services provided patients defined as having at least one inpatient or outpatient...
The recent advancements in large language models (LLMs) have brought significant changes to the field of education, particularly generation and evaluation feedback. LLMs are transforming education by streamlining tasks like content creation, feedback generation, assessment, reducing teachers’ workload improving online efficiency. This study aimed verify consistency reliability as evaluators conducting automated evaluations using various based on five educational criteria. analysis revealed...
Abstract Background Understanding the health status of North Korean refugees (NKRs), and changes in during resettlement process, is important from both humanitarian standpoint scientific perspective. The NOrth Refugee iN South Korea (NORNS) study aims to document determinants refugees, observe various outcomes as they occur while adapting westernized lifestyle Korea, explain mechanisms how migrants context new environmental risks opportunities. Methods NORNS was composed an initial survey a...
The purpose of this study was to investigate the clustering pattern four major lifestyle risk factors-smoking, heavy drinking, poor diet, and physical inactivity-among people with metabolic syndrome in South Korea. There were 2,469 adults aged 30 years or older available 5th Korean National Health Nutrition Examination Survey dataset. We calculated ratio observed expected (O/E) prevalence for 16 different combinations odds ratios (POR) factors. factors tended cluster specific multiple...
Demonstrating the value of spine care requires adequate outcomes assessment. Long-term are best measured as overall improvement in quality life (QOL) after surgical intervention. Present registries often require parallel data entry, introducing inefficiencies and limiting compliance. The authors detail methodology constructing an integrated electronic health record (EHR) system to collect QOL metrics demonstrate effect collection on routine clinical workflow. A streamlined approach...
In 2010, ischemic heart disease was the leading cause of disability-adjusted life-years (DALYs) worldwide. More specially, prevalence acute myocardial infarctions (AMI) is increasing in aged population as mortality decreases; South Korea no exception. This study aims to examine economic burden AMI Korean between 2007 and 2012. AMI-related costs were assessed from a societal perspective. A prevalence-based cost-of-illness framework used for this analysis. The subjects included all Koreans...
Purpose This study estimates the socioeconomic cost and burden for breast cancer patients in Korea between 2007 2010. Materials Methods used a prevalence-based approach to estimate of cancer. Breast were defined as those who hospitalized or have visited an outpatient clinic during period from The costs subdivided into two costs: direct indirect. Results From 2010, prevalence treated increased 7.9% 20.4%. total incurred by approximately 40.7% US $668.49 million $940.75 medical care 2010 1.4...
Even with a reduced burden of malaria in sub-Saharan Africa (SSA), differences remain the rate change among countries and sub-regions. We used data from Global Burden Disease Study 2019 to establish relationship between Development Assistance for Health (DAH) governance trends SSA. The trend was estimated using Joinpoint regression program Institute Metrics Evaluation's DAH database, World Bank Governance Indicators analyze respectively 2000 2017 two-way fixed effects their association...
The incidence of complications associated with cerebrovascular diseases in patients who receive hemodialysis for a long-term period is higher than that other complications. It known mortality due to cerebral hemorrhage two times compared non-dialysis patients. Anti-coagulants used are essential. Accordingly, cases which the occurred, selection anti-coagulants prevention further bleeding poses great challenge physicians. change hematoma and patient prognosis has direct relationship. Many...
This study aims to determine the effectiveness of paliperidone extended release (ER) on cognitive function in patients with schizophrenia comparison risperidone. was a 12-week, randomized, open-label who were receiving The randomized risperidone-continuation group or paliperidone-switch group. primary outcome measure neurocognitive function, which measured using computerized battery. Secondary efficacy measures included Positive and Negative Syndrome Scale, Social Occupational Functioning...
This study aimed to examine the degree of clinical and functional improvement after paliperidone long-acting injectable (LAI) administration according duration illness.Patients with schizophrenia diagnosed by ICD-10 criteria who were planned start once-monthly LAI recruited from 2010 2017. Clinical changes measured every 4 weeks using Global Impressions-Severity Illness scale (CGI-S) Personal Social Performance (PSP), respectively, for 6 months initiation. Improvements starting compared...
Objectives The incidence and survival rate of colorectal cancer in Korea are increasing because improved screening, treatment technologies, lifestyle changes. In this aging population, increases economic cost result. This study was conducted to estimate the burden utilizing claims data from Health Insurance Review Assessment Service. Methods Economic burdens were estimated using prevalence patients defined as those who received ambulatory medical institutions or had been hospitalized due...
This article evaluates the overall current disease burden of North Korea through recent databases international organizations. It is notable that as a nation exhibiting relatively low from deaths and there greater caused by non-communicable diseases than those communicable malnutrition. However, absolute magnitude problems like TB child malnutrition, which will increase in future, remains great. Korea, needs to handle both nutritional conditions, diseases, whose ever more increasing nation,...
Background: Serum selenium levels are lower in critically ill patients as compared with healthy controls. However, there is no data about the difference serum depending on severity of lung diseases. We aimed to identify factors associated low respiratory
Suicide in the working-age population is an important public health issue. This group heterogeneous regarding marital status, education level, and employment which are generally socioeconomic factors for suicide, has a wide age range. study aims to explore individual combined effect of these on suicide different groups among population.This utilized population-based case-control design South Korea. cases were identified Korean Governmental Death Registry from 2008 2017, eight controls Korea...