Jacek A Kopec
A5101665680- Global Health Care Issues
- Global Public Health Policies and Epidemiology
- Health disparities and outcomes
- Global Maternal and Child Health
- Climate Change and Health Impacts
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Reforms
- Musculoskeletal pain and rehabilitation
- Trauma and Emergency Care Studies
- Colorectal Cancer Treatments and Studies
- HIV/AIDS Research and Interventions
- Cancer Treatment and Pharmacology
- Vascular Malformations and Hemangiomas
- HIV, Drug Use, Sexual Risk
- Insurance, Mortality, Demography, Risk Management
- Global Cancer Incidence and Screening
- Colorectal Cancer Surgical Treatments
- Spine and Intervertebral Disc Pathology
- Injury Epidemiology and Prevention
- HIV/AIDS Impact and Responses
- Air Quality and Health Impacts
- Child Nutrition and Water Access
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal Disorders and Rehabilitation
- HIV Research and Treatment
University of British Columbia
2007-2024
The University of Sydney
2023-2024
Northern Sydney Local Health District
2024
Royal North Shore Hospital
2023-2024
Institute for Health Metrics and Evaluation
2023-2024
Institute for Musculoskeletal Health
2023-2024
Wenzhou Medical University
2024
Research Canada
2020-2023
Central Queensland University
2023
Medical University of Lodz
2020-2023
Alcohol and drug use can have negative consequences on the health, economy, productivity, social aspects of communities. We aimed to data from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2016 calculate global regional estimates prevalence alcohol, amphetamine, cannabis, cocaine, opioid dependence, estimate disease burden attributable alcohol between 1990 2016, for 195 countries territories within 21 regions, seven super-regions. also examine association Socio-demographic Index...
Low back pain is highly prevalent and the main cause of years lived with disability (YLDs). We present most up-to-date global, regional, national data on prevalence YLDs for low from Global Burden Diseases, Injuries, Risk Factors Study 2021.Population-based studies 1980 to 2019 identified in a systematic review, international surveys, US medical claims data, dataset contributions by collaborators were used estimate 1990 2020, 204 countries territories. was defined as between 12th ribs...
Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death disability due to musculoskeletal disorders, Global Burden of Diseases, Injuries, Risk Factors Study (GBD) includes a residual category for other osteoarthritis, rheumatoid arthritis, gout, low back pain, neck pain. This is called includes, example, systemic lupus erythematosus spondylopathies. We provide updated...
Background Neck pain is a highly prevalent condition that leads to considerable pain, disability, and economic cost.We present the most current estimates of neck prevalence years lived with disability (YLDs) from Global Burden Diseases, Injuries, Risk Factors Study (GBD) by age, sex, location, forecasted 2050. MethodsSystematic reviews identified population-representative surveys used estimate YLDs in 204 countries territories, spanning 1990 2020, additional data opportunistic review.Medical...
Background: Low back pain is highly prevalent and the number one cause of years lived with disability (YLDs). We present most up-to-date global, regional, national data on prevalence YLDs for low from Global Burden Diseases, Injuries, Risk Factors 2021 Study. Methods: Population-based studies 1980 to 2019 identified in a systematic review, international surveys, USA claims data, dataset contributions by collaborators were used estimate 1990 2021, 204 countries territories. was defined as...
<h2>Summary</h2><h3>Background</h3> Gout is an inflammatory arthritis manifesting as acute episodes of severe joint pain and swelling, which can progress to chronic tophaceous or erosive gout, both. Here, we present the most up-to-date global, regional, national estimates for prevalence years lived with disability (YLDs) due gout by sex, age, location from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2021, well forecasted 2050. <h3>Methods</h3> YLDs 1990 2020 were estimated...
Purpose The randomized, multicenter, phase III protocol C-07 compared the efficacy of adjuvant bolus fluorouracil and leucovorin (FULV) versus FULV with oxaliplatin (FLOX) in stage II or colon cancer. Definitive analysis revealed an increase 4-year disease-free survival from 67.0% to 73.2% favor FLOX. This study compares neurotoxicity between treatments. Patients Methods Neurotoxicity was recorded for all patients using standard adverse event reporting. at select institutions completed a...
Recent research has identified younger women as an "at-risk" population with rising prevalence of cardiac risk factors and excess mortality following acute myocardial infarction (AMI). However, population-based data on trends in AMI hospitalization early post among adults is scarce. We, therefore, aimed to provide a 10-year, descriptive analysis these Canadian setting.We assessed sex differences 30-day rates using negative binomial logistic regression, respectively. From 2000 2009, there...
We used findings from the Global Burden of Disease Study 2013 to report burden musculoskeletal disorders in Eastern Mediterranean Region (EMR).The was calculated for EMR's 22 countries between 1990 and 2013. A systematic analysis performed on mortality morbidity data estimate prevalence, death, years live lost, lived with disability disability-adjusted life (DALYs).For disorders, crude DALYs rate per 100 000 increased 1297.1 (95% uncertainty interval (UI) 924.3-1703.4) 1606.0 UI...
Neurotoxicity from adjuvant treatment with oxaliplatin has been studied in patients colorectal carcinoma short-term studies, but, to the authors' knowledge, current article is first long-term assessment which reports National Surgical Adjuvant Breast and Bowel Project (NSABP) investigation of whether excess neurotoxicity persists beyond 4 years.As part a cancer survivor study (LTS-01), was assessed 353 on NSABP Protocol C-07 (cross-sectional sample). Ninety-two these LTS-01 also had...
Following the economic crisis in Greece 2010, country's ongoing austerity measures include a substantial contraction of health-care expenditure, with reports subsequent negative health consequences. A comprehensive evaluation mortality and morbidity is required to understand current challenges public Greece.We used results Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2016 describe patterns death disability among those living from 2000 2010 (pre-austerity) (post-austerity),...
Systematic collection of mortality/morbidity data over time is crucial for monitoring trends in population health, developing health policies, assessing the impact programs. In Poland, a comprehensive analysis describing disease burden major conditions has never been published. The Global Burden Diseases, Injuries, and Risk Factors Study (GBD) provides on 300 diseases 195 countries since 1990. We used GBD database to undertake an assessment evaluate changes between 1990-2017, compare Poland...
Abstract Background We described the impact of different lengths lookback window (LW), a retrospective time period to observe diagnoses in administrative data, on prevalence and incidence eight chronic diseases. Methods Our study populations included people living with HIV ( N = 5151) 1:5 age-sex-matched HIV-negative individuals 25,755) British Columbia, Canada, complete follow-up between 1996 2012. measured diseases 2012 using LWs ranging from 1 16 years. Cases were deemed prevalent if...
The burden of ischemic heart disease (IHD) is high. There limited information on the IHD in identified high risk areas like Central Asia (CA) which comprised Armenia, Azerbaijan, Georgia, Kazakhstan, Kyrgyzstan, Turkmenistan, Mongolia, Uzbekistan and Tajikistan. This study addresses CA at regional country levels.Using data from latest iteration Global Burden Disease Study (GBD), this provides age-adjusted mortality, prevalence, Disability Adjusted Life Years (DALYs) by sex region, national...
8080 Background: The NSABP C-06 trial demonstrated that adjuvant therapy with oral uracil/ftorafur (UFT) + leucovorin (LV) is equivalent to standard intravenous regimen of 5-fluorouracil (5-FU) LV in terms disease-free survival and overall patients stage II III carcinoma the colon. This study compared health-related quality life (HRQL), convenience care (COC) symptoms two arms C-06. Methods: HRQL was measured Functional Assessment Cancer Therapy, Colon (FACT-C) questionnaire, plus SF-36...
<b><br>Aim:</b> The aim of this retrospective study was to evaluate our treatment for pilonidal disease in adolescent patients, which uses ultrasonography, minimally invasive pit-picking, and Nd:YAG laser therapy.</br> <b><br>Material methods:</b> We included 52 147 patients treated between June 2017 December 2020. underwent pit-picking procedures 6–10 treatments. remnants the cysts were removed by therapy, provided easy epilation. Each patient...
Vascular anomalies often result in aesthetic flaws, pain, and impair the quality of life. They require challenging treatments that frequently do not provide desired results. The mammalian target rapamycin (mTOR) is directly involved development these malformations. However, exact mechanism behind mTOR dysregulation has been unambiguously defined. purpose this study to investigate activation selected substrates partially assess its involvement disease process.
Advances in laser techniques used medicine significantly expanded the pool of procedures as well increased frequency and ease their use.Paediatric surgery is one branches open to use dynamically developing technologies.Based on current literature our own experiences, we present a cross-sectional review modern applications therapy paediatric population.Laser often complementary other treatment methods and, many cases, it becomes main approach variety conditions.It an indispensable element...