- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Genetic factors in colorectal cancer
- Cancer-related gene regulation
- Glioma Diagnosis and Treatment
- Genetic Syndromes and Imprinting
- Kruppel-like factors research
- Pancreatic function and diabetes
- HER2/EGFR in Cancer Research
- Occupational and environmental lung diseases
- Metabolism, Diabetes, and Cancer
- Esophageal and GI Pathology
- Lung Cancer Treatments and Mutations
- Diabetes Treatment and Management
- Hip disorders and treatments
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
Northwest University
2015-2024
Ministry of Education of the People's Republic of China
2016-2024
Xizang Minzu University
2020
University of Nottingham Ningbo China
2015
First Affiliated Hospital of Xi'an Jiaotong University
2015
AIM:To investigate the association between colorectal cancer (CRC) genetic susceptibility variants and esophageal in a Chinese Han population. METHODS:A case-control study was conducted including 360 patients 310 healthy controls.Thirty-one single-nucleotide polymorphisms (SNPs) associated with CRC risk from previous genome-wide studies were analyzed.SNPs genotyped using Sequenom Mass-ARRAY technology, genotypic frequencies controls tested for departure Hardy-Weinberg equilibrium Fisher's...
// Jing Li 1, * , Jiachen Wei 2, Pengcheng Xu 3 Mengdan Yan 4 Jingjie Zhengshuai Chen Tianbo Jin 1 Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry Education, School Life Sciences, Northwest University, Xi'an, Shaanxi 710069, 2 Department Endocrinology, Xi'an NO.1 Hospital, 710002, Inner Mongolia Medical Mongolia, Hohhot 010010, Tiangen Precision Institute, Shaanxi, 710075, These authors have contributed equally to this work...
Single nucleotide polymorphisms (SNPs) in TERT may be associated with susceptibility to esophageal cancer. In this study, we analyzed the association between SNPs and risk of cancer 386 patients 495 healthy subjects from Xi'an area China. Of four examined, rs10069690 rs2242652 were correlated risk. Additionally, after adjusting for age gender, "Trs10069690Ars2242652", "Trs10069690Grs2242652" haplotypes an increased cancer, while "Crs10069690Grs2242652" haplotype was a decreased These...
// Bin Li 1, 2, * , Wenhui Zhao 3, Jingjie 2 Mengdan Yan Zhilan Xie Yuanyuan Zhu Chao Chen Tianbo Jin 4 1 School of Life Sciences, Northwest University, Xi'an, Shaanxi, 710069, China National Engineering Research Center for Miniaturized Detection Systems, 3 Department Anesthesiology, Shaanxi Provincial Tumor Hospital, 710061, Xi'an Tiangen Precision Medical Institute, 710075, These authors have contributed equally to this work Correspondence to: Jin, email: jintianbo@gmail.com Chen,...
Previous studies showed an association between the ZNF208 gene and gastric cancer. In this study, we investigated single nucleotide polymorphisms (SNPs) in risk of esophageal cancer a Chinese Han population. We conducted case-control study that included 386 cases 495 controls. Five SNPs were selected from previous genome-wide genotyped using Sequenom MassARRAY platform. Unconditional logistic regression was used to calculate odds ratios 95% confidence intervals after adjustment for age...
<b><i>Introduction:</i></b> <i>SMG5</i> is involved in tumor cell development and viewed as a potential target for immunotherapy. The purpose of this study was to systematically analyze the expression level, function, prognostic value pan-cancers. <b><i>Methods:</i></b> Differential normal tissues analyzed using Cancer Genome Atlas (TCGA) Genotype-Tissue Expression Database (GTEx) data. Survival analysis performed by Kaplan-Meier...
Esophageal carcinoma (EC) is a common malignancy worldwide. Previous studies indicated that gastrointestinal gland cancer and EC share some susceptibility loci. Our aim was to identify new single nucleotide polymorphisms (SNPs) associated with by investigating whether known cancers loci are found in patients. A Chinese Han population case-control study conducted assess SNP associations risk. Twenty-six SNPs were selected from loci, 360 patients 310 controls genotyped for these using Sequenom...
Abstract Background The present study investigated whether 16 single nucleotide polymorphisms (SNPs), selected based on minor allele frequencies, Hardy–Weinberg equilibrium and reported SNPs related to the susceptibility of certain gastrointestinal cancer, were associated with esophageal cancer (EC) risk in a Chinese Han population. Methods We genotyped among 506 cases 507 controls using Agena MassARRAY (Agena, San Diego, CA, USA). association between EC was analyzed by chi‐squared test...
Objectives Krüppel‑like factors (KLFs) are implicated in the progression of endometrial cancer (EC). This present study explored correlation between variants KLF5, KLF12 and EC risk Chinese population.