- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Brain Metastases and Treatment
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Vascular Tumors and Angiosarcomas
- Urinary Bladder and Prostate Research
- Prostate Cancer Treatment and Research
- Meningioma and schwannoma management
- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Welding Techniques and Residual Stresses
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Dental Radiography and Imaging
- Nonmelanoma Skin Cancer Studies
The University of Tokyo
2023-2025
Osaka International Cancer Institute
2017-2025
Tokyo Metropolitan University
2024-2025
Osaka University
2015-2024
University of Tokyo Hospital
2023-2024
Kawasaki Medical School
2011-2022
Osaka Medical Center for Cancer and Cardiovascular Diseases
2014-2017
Erasmus MC Cancer Institute
2016
Shinshu University
2004-2013
Ōtani University
2013
The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared dosimetric parameters HA-VMAT plan with those conventional (C-VMAT).For 23 patients (1-4 metastases), C-VMAT and plans a prescription 20-24 Gy were retrospectively generated, PTV (homogeneity index, HI; conformity CI; gradient GI) tissue (V2Gy-V16Gy) evaluated. Subsequently, physical characteristics (modulation complexity score...
In stereotactic radiosurgery (SRS) with single-isocentric treatments for brain metastases, rotational setup errors may cause considerable dosimetric effects. We assessed the effects on HyperArc plans single and multiple metastases.For 29 patients (1-8 metastases), a prescription dose of 20-24 Gy that covers 95% (D95% ) planning target volume (PTV) were retrospectively generated (Ref-plan). Subsequently, computed tomography (CT) used Ref-plan cone-beam CT acquired during (Rot-CT) registered....
Background/Aim: This study investigated the survival outcomes of patients with head and neck squamous cell carcinoma (HNSCC) undergoing palliative radiotherapy, particularly focusing on challenges factors associated older age, providing insights into appropriate radiotherapy use in this demographic. Patients Methods: A retrospective was conducted using electronic medical records 73 HNSCC who were deemed unsuitable for curative therapy. Palliative involved a uniform dose 30 Gy 10 fractions....
A novel linac-bases radiosurgery (SRS) system, HyperArc, applied to the non-coplanar volume-modulated arc therapy (VMAT) technique, was developed and released in clinical practice. The aim of study evaluate dosimetric performance brain sparing single-target three-target cases, for two types SRS systems: GammaKnife HyperArc. total 83 patients treated with (35 single, 24 double, triple metastases) were retrospectively analyzed. Treatment plans recalculated using Dosimetric parameters,...
Abstract Purpose This study aims to quantify and compare the dosimetric effects of varying thicknesses StrataXRT, a silicone‐based gel, other topical agents on skin surface during volumetric modulated arc therapy (VMAT) for breast cancer. Methods A VMAT plan was created cancer treatment using female RANDO phantom with prescription dose 50 Gy in 25 fractions. The planning target volume (PTV) encompassed left regional lymph nodes. Irradiation performed 6 MV photon beam. Three (StrataXRT,...
Abstract Background The breath‐hold radiotherapy has been increasingly used to mitigate interfractional and intrafractional breathing impact on treatment planning beam delivery. Previous techniques include body surface measurements or radiopaque metal markers, each having known disadvantages. Purpose We recently proposed a new markerless technique without the disadvantages, where diaphragm was registered between DRR fluoroscopic x‐ray projection images every 180 ms during VMAT An initial...
Health literacy (HL) plays a vital role in an individual's ability to make informed health decisions. Japan faces several challenges cervical cancer control, including low human papillomavirus (HPV) vaccination and screening rates, underutilization of radiotherapy, limited HL. This study explored the association between HL knowledge particularly among young Japanese women. We conducted web-based survey users LunaLuna, popular women's healthcare application, assess their about radiotherapy...
We report a case of extramammary Paget's disease with underlying adenocarcinoma simulating breast carcinoma the vulva. An 82-year-old woman was found to have 5 x 3-cm bulky tumor located in left labium major, infiltrating clitoris, minor, and lateral tissue Small biopsy vulva showed intraepidermal proliferation Paget cells. The patient underwent wide local excision vulvar dissection inguinal lymph nodes. Histopathological examination resected specimens revealed that cells were distributed...
Abstract Purpose This study investigated the intra‐fractional motion (IM) of patients immobilized using QFix Encompass Immobilization System during HyperArc (HA) treatment. Method HA treatment was performed on 89 Encompass. The IM (including megavoltage (MV) registration) analyzed for six degrees freedom including three axes translation (anterior‐posterior, superior‐inferior (SI) and left‐right (LR)) rotation (pitch, roll, yaw). Then, no corrected (IM NC ) retrospectively simulated...
Abstract Background and Purpose Few reports include volumetric measurements as endpoints after stereotactic radiotherapy (SRT) despite the importance of such measurements. This study aimed to (1) investigate impact response (specifically, an over 65% 90% volume reduction in brain metastases) at 6 months post‐SRT on local control (2) identify predictive factors for a 90%. Materials Methods included 250 unresected metastases (>0.3 cc) treated with SRT. Doses were stratified according...
The purpose of the study is to investigate variation in Hounsfield unit (HU) values calculated using dual-energy computed tomography (DECT) scanners. A tissue characterization phantom inserting 16 reference materials were scanned three times DECT scanners [dual-layer CT (DLCT), dual-source (DSCT), and fast kilovoltage switching (FKSCT)] changing scanning conditions. single-energy images (120 or 140 kVp), virtual monochromatic at 70 keV (VMI70) (VMI140) reconstructed, HU each material...
Abstract Purpose To compare the intrafractional motion error (IME) during stereotactic irradiation (STI) in patients with brain metastases immobilized using open‐ (Encompass) and full‐face (DSPS) clamshell‐style immobilization devices. Methods Encompass (38 patients) DSPS were used for patient immobilization, HyperArc plans three to four non‐coplanar beams generated deliver 25 35 Gy five fractions. Cone‐beam computed tomography (CBCT) was performed on before after treatment. Moreover,...
Background: This study aimed to evaluate knowledge-based volume modulated arc therapy (VMAT) plans for oesophageal cancers using a model trained with optimised different treatment planning system (TPS) and compare lung dose sparing in two TPSs, Eclipse RayStation.Materials methods: A total of 64 patients stage I-III were treated hybrid VMAT (H-VMAT) RayStation. Among them, 40 used training the (KBP) RapidPlan. The remaining 24 recalculated RapidPlan validate KBP model. H-VMAT calculated...