Dong‐Aolei An

ORCID: 0000-0002-6195-2246
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Advanced MRI Techniques and Applications
  • Cardiovascular Effects of Exercise
  • Cardiomyopathy and Myosin Studies
  • Acute Myocardial Infarction Research
  • Cardiac Structural Anomalies and Repair
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Sports injuries and prevention
  • Coronary Interventions and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Advanced X-ray and CT Imaging
  • Ultrasound and Hyperthermia Applications
  • Cardiovascular Disease and Adiposity
  • Advanced Neuroimaging Techniques and Applications
  • Viral Infections and Immunology Research
  • Cardiac Arrest and Resuscitation
  • Advancements in Semiconductor Devices and Circuit Design
  • Systemic Lupus Erythematosus Research
  • Iron Metabolism and Disorders
  • Cerebrovascular and Carotid Artery Diseases
  • Long-Term Effects of COVID-19
  • Erythropoietin and Anemia Treatment

Shanghai Jiao Tong University
2015-2024

Renji Hospital
2015-2024

Zero to Three
2018

In order to determine acute cardiac involvement in patients with COVID-19, we quantitatively evaluated tissue characteristics and mechanics by non-invasive magnetic resonance (CMR) a cohort of within the first 10 days onset COVID symptoms.Twenty-five reverse transcription polymerase chain reaction confirmed COVID-19 at least one marker [cardiac symptoms, abnormal electrocardiograph (ECG), or biomarkers] 25 healthy age- gender-matched control subjects were recruited study. Patients divided...

10.1093/ehjci/jeab042 article EN other-oa European Heart Journal - Cardiovascular Imaging 2021-02-26

The prognostic value of left ventricular (LV) myocardial trabecular complexity on cardiovascular magnetic resonance (CMR) in dilated cardiomyopathy (DCM) remains unknown. This study aimed to evaluate the LV using fractal analysis patients with DCM. Consecutive DCM who underwent CMR between March 2017 and November 2021 at two hospitals were prospectively enrolled. primary endpoints defined as combination all-cause death heart failure hospitalization. events cardiac alone secondary...

10.1016/j.jocmr.2024.101005 article EN cc-by-nc-nd Journal of Cardiovascular Magnetic Resonance 2024-01-01

BACKGROUND: Late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) is a standard technique for diagnosing myocardial infarction (MI), which, however, poses risks due to contrast usage. Techniques enabling MI assessment based on contrast-free CMR are desirable overcome the limitations associated with enhancement. METHODS: We introduce novel deep generative learning method, termed cine-generated (CGE), which transforms cine into LGE-equivalent images assessment. CGE features...

10.1161/circimaging.124.016786 article EN Circulation Cardiovascular Imaging 2024-09-10

Objective: In this paper, we propose a fully automatic framework for myocardium segmentation of delayed-enhancement (DE) MRI images without relying on prior patient-specific information. Methods: We employ multicomponent Gaussian mixture model to deal with the intensity heterogeneity caused by infarcts. To differentiate from other tissues similar intensities, while at same time maintain spatial continuity, introduce coupled level set (CLS) regularize posterior probability. The CLS, as...

10.1109/tbme.2017.2657656 article EN IEEE Transactions on Biomedical Engineering 2017-01-24

Background Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive myocardial fibro‐fatty infiltration accompanied trabecular disarray. Traditionally, two‐dimensional (2D) instead of 3D fractal dimension (FD) analysis has been used to evaluate However, the prognostic value disorder assessed FD measurement remains unclear. Purpose To investigate right ventricular complexity in ACM patients using based on cardiac MR cine images. Study Type Retrospective. Population 85 (mean age: 45...

10.1002/jmri.29237 article EN Journal of Magnetic Resonance Imaging 2024-01-23

In arrhythmogenic cardiomyopathy (ACM), left ventricle-dominant presentation has poorer outcomes than right-dominant presentation, suggesting that interventricular functional disparity might play a role in patients' prognosis. However, the prognostic impact of ventricular discordance ACM patients remains unknown.

10.1002/jmri.29699 article EN Journal of Magnetic Resonance Imaging 2024-12-30

Increased pericardial adipose tissue (PEAT) is associated with a series of cardiovascular diseases (CVDs) and metabolic syndromes. Quantitative analysis PEAT by means image segmentation great significance. Although magnetic resonance (CMR) has been utilized as routine method for non-invasive non-radioactive CVD diagnosis, in CMR images challenging laborious. In practice, no public datasets are available validating automatic segmentation. Therefore, we first release benchmark dataset, MRPEAT,...

10.1109/tmi.2023.3251368 article EN IEEE Transactions on Medical Imaging 2023-03-02

This study assessed the extent of fibrosis and relationship between ADC value systolic strain in hypertensive patients with left ventricular hypertrophy (HTN LVH) without LVH non-LVH) using cardiac diffusion-weighted imaging T1 mapping. mapping was performed 13 HTN (mean age, 56.23 ± 3.30 years), 17 non-LVH 56.41 2.78 12 normal control subjects 55.67 3.08 years) 3.0 T MRI had higher native (1233.12 79.01) compared controls (1133.88 27.40) (p < 0.05). ECV (0.28 0.03) (0.26 0.02) or (0.24...

10.1038/s41598-017-00627-5 article EN cc-by Scientific Reports 2017-03-28

Background Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide places significant financial burden on our society. Purpose To determine the feasibility cardiac intravoxel incoherent motion (IVIM) in consecutive evaluation perfusion patients postpercutaneous coronary intervention (PCI) to investigate dynamic biological phenomena after AMI. Study Type Prospective observational study. Population Twenty ST‐segment elevation (STEMI) reperfusion therapy 12...

10.1002/jmri.26179 article EN Journal of Magnetic Resonance Imaging 2018-05-07

Abstract Aims The prognostic implication of left ventricular (LV) torsion on ST-elevation myocardial infarction (STEMI) is unclear. Methods and results We analysed cardiovascular magnetic resonance (CMR) findings 420 patients from a registry study (NCT03768453). These received CMR examination within 1 week after timely primary percutaneous coronary intervention. LV other indexes were measured. Compared with healthy control subjects, STEMI significantly decreased patients’ (1.04 vs. 1.63°/cm,...

10.1093/ehjci/jeac177 article EN European Heart Journal - Cardiovascular Imaging 2022-09-03

Abstract Objectives Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited characterized by progressive fibrofatty infiltration of atrial and myocardium resulting in adverse cardiac events. Atrial function has been increasingly recognized as prognostically important for cardiovascular disease. As the (RA) strain a sensitive parameter to describe RA function, we aimed analyze prognostic value ARVC. Methods parameters were derived from magnetic resonance (CMR) images 105...

10.1186/s13244-024-01630-x article EN cc-by Insights into Imaging 2024-02-27

Background Previous studies have shown that diffusion‐weighted imaging (DWI) is sensitive to myocardial fibrosis in ischemic and nonischemic cardiomyopathy. Purpose To explore the prognostic value of apparent diffusion coefficient (ADC) for detecting its relationship contractile function hypertrophic cardiomyopathy (HCM). Study Type Prospective. Population A total 45 HCM patients 20 controls. Field Strength/Sequence 3.0T cardiac MRI. The MR sequences included cine, T 1 mapping, DWI....

10.1002/jmri.26016 article EN Journal of Magnetic Resonance Imaging 2018-03-30

Background Left ventricular global function index (LVGFI) integrates LV volumetric and functional parameters. In patients with end‐stage renal disease (ESRD), cardiac injury manifests as hypertrophy dysfunction. However, the prognostic value of LVGFI in this population remains unclear. Purpose To investigate association major adverse events (MACE) ESRD. Study Type Prospective. Population One hundred fifty‐eight ESRD (mean age: 54.1 ± 14.4 years; 105 male) on maintenance dialysis. Filed...

10.1002/jmri.28979 article EN Journal of Magnetic Resonance Imaging 2023-09-05

Background The relationship between dynamic changes of myocardial injury in ST‐elevation infarction (STEMI) patients and long‐term prognosis is still unclear. Purpose To evaluate the extracellular volume fraction (ECV) differentiation reversible from irreversible prediction value left ventricular adverse remodeling with STEMI after reperfusion. Study Type Prospective. Population Twenty‐four reperfusion were included Field Strength/Sequence 3.0 T, T 1 mapping, ECV, 2 ‐STIR, late gadolinium...

10.1002/jmri.27047 article EN Journal of Magnetic Resonance Imaging 2020-01-14

Background The impact of left ventricular mechanical dyssynchrony (LVMD) on the long‐term prognosis ST‐segment elevation myocardial infarction (STEMI) is unclear. Hypothesis MR uniformity ratio estimates (URE) can detect LVMD and assess STEMI prognosis. Study Type Retrospective analysis a prospective multicenter registry (EARLY‐MYO trial, NCT 03768453). Population Overall, 450 patients (50 females) with first‐time were analyzed, as well 40 participants without cardiovascular disease...

10.1002/jmri.28998 article EN Journal of Magnetic Resonance Imaging 2023-10-13
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