A5029790581- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Genomics and Rare Diseases
- Cerebrovascular and genetic disorders
- Restraint-Related Deaths
- Genomic variations and chromosomal abnormalities
- Injury Epidemiology and Prevention
- Traumatic Ocular and Foreign Body Injuries
- Genetics and Neurodevelopmental Disorders
Singapore Eye Research Institute
2021-2023
Singapore National Eye Center
2021-2023
Nethradhama Superspeciality Eye Hospital
2019
Sankara Nethralaya
2016-2017
To assess 5-year cumulative incidence and risk factors of fellow eye involvement in Asian neovascular age-related macular degeneration (nAMD) polypoidal choroidal vasculopathy.In a prospective cohort study nAMD vasculopathy, the eyes were evaluated for exudation. The exudation was compared between vasculopathy.A total 488 patients studied. 16.2% (95% confidence interval: 12.0-20.2). Polypoidal vasculopathy with first associated lower progression (9.8% [95% 5.1-14.3]) vs. 22.9% 15.8-29.3], P...
Abstract The aim of this study was to evaluate influence baseline imaging features on visual and anatomical outcomes in eyes with PCV treated anti-VEGF monotherapy. In prospective we enrolled participants treatment-naïve who followed a treat-and-extend protocol using intravitreal aflibercept (IVA) Baseline clinical evaluatedincluded best corrected acuity (BCVA), traditional such as lesion size, fluid-related OCT parameters novel automated software. This included quantitative qualitative...
Aim To describe the clinical characteristics in a cohort of patients with pachychoroid phenotype and to evaluate association ocular systemic factors type complications observed. Methods We report baseline findings from prospective observational study which recruited subjects subfoveal choroidal thickness (SFCT) ≥300 µm on spectral-domain optical coherence tomography (OCT). Multimodal imaging was used classify eyes as uncomplicated (UP) or disease pigment epitheliopathy (PPE), central serous...
To compare treatment outcomes for myopic choroidal neovascularisation (CNV) managed with verteporfin photodynamic therapy (vPDT), intravitreal antivascular endothelial growth factor (anti-VEGF, bevacizumab/ranibizumab) agents or combination thereof.Clinical data of 79 eyes CNV examined from March 2004 to July 2013 was retrospectively reviewed. Patients were vPDT, bevacizumab (1.25 mg/0.05 mL)/ranibizumab (0.5 mL) a vPDT and anti-VEGF. Outcome measures included complete regression (scarring)...
"Bilateral focal choroidal excavation in cone dystrophy." Clinical and Experimental Optometry, 99(2), pp. 198–199
Intact foveal bulge has been associated with good visual outcome in retinal diseases. The aim of this study was to the variation age.It an observational cross-sectional conducted between October 2014 and December 2015. Totally, 101 eyes healthy volunteers were studied a tertiary care center. All individuals had best corrected acuity 20/20 or better. High myopia (>6 D), high hyperopia (>4 unstable fixation, media opacities disorder like diabetic retinopathy, vein occlusion exclusion criteria....
To compare the efficacy and safety of intravitreal aflibercept (IVA) monotherapy versus combined with reduced-fluence photodynamic therapy (RF-PDT) (IVA+RF-PDT) for treatment polypoidal choroidal vasculopathy (PCV).Multicentred, double-masked, randomised controlled trial to two modalities. The primary outcome study is 52-week visual IVA IVA+RF PDT. One hundred sixty treatment-naïve patients macular PCV confirmed on indocyanine green angiography will be recruited from three centres in...
To evaluate whether optical coherence tomography (OCT) can determine polypoidal lesion (PL) perfusion in choroidal vasculopathy eyes after 12 months of aflibercept monotherapy. Polypoidal status, assessed by indocyanine green angiography, is an important anatomical outcome management.Post hoc data from a prospective randomized, open-label, study with undergoing monotherapy evaluated PL status based on angiography (gold standard) and OCT features baseline to months.Individual PLs (110 total)...