A5035786839- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- CRISPR and Genetic Engineering
- Viral Infections and Immunology Research
- Virology and Viral Diseases
- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- Vibrio bacteria research studies
- Hepatitis Viruses Studies and Epidemiology
- Identification and Quantification in Food
- Marine Bivalve and Aquaculture Studies
- Plant Virus Research Studies
- Viral Infections and Vectors
- Viral Infectious Diseases and Gene Expression in Insects
- Livestock and Poultry Management
- Vector-Borne Animal Diseases
- Food Supply Chain Traceability
- Veterinary medicine and infectious diseases
- Virus-based gene therapy research
- Agronomic Practices and Intercropping Systems
- Bacteriophages and microbial interactions
- Animal Disease Management and Epidemiology
- Salmonella and Campylobacter epidemiology
- Aquaculture Nutrition and Growth
- Aquatic Invertebrate Ecology and Behavior
University of Florida
2020-2023
Azienda-Unita' Sanitaria Locale Di Cesena
2017
University of Bologna
2009-2017
Ifremer
2012-2014
GNA University
2007
Abstract Background The COVID-19 pandemic has resulted in 275 million infections and 5.4 deaths as of December 2021. While effective vaccines are being administered globally, there is still a great need for antiviral therapies antigenically novel SARS-CoV-2 variants continue to emerge across the globe. Viruses require host factors at every step their life cycle, representing rich pool candidate targets drug design. Methods To identify that promote infection with potential broad-spectrum...
ABSTRACT Hepatitis E virus (HEV), an enteric pathogen of both humans and animals, is excreted by infected individuals therefore present in wastewaters coastal waters. As bivalve molluscan shellfish are known to concentrate viral particles during the process filter feeding, they may accumulate this virus. The bioaccumulation efficiencies oysters ( Crassostrea gigas ), flat Ostrea edulis mussels Mytilus clams Ruditapes philippinarum ) were compared at different time points year. Tissue...
Noroviruses are the leading cause of severe childhood diarrhea and foodborne disease worldwide. While they a major in all age groups, infections very young can be quite severe, with annual estimates 50,000-200,000 fatalities children under 5 years old. In spite remarkable burden associated norovirus infections, little is known about pathogenic mechanisms underlying diarrhea, principally because lack tractable small animal models. The development murine (MNV) model nearly two decades ago has...
Norovirus is the most common agent implicated in food-borne outbreaks and frequently detected environmental samples. These viruses are highly diverse, three genogroups (genogroup I [GI], GII, GIV) infect humans. Being noncultivable viruses, real-time reverse transcription-PCR (RT-PCR) only sensitive method available for their detection food or Selection of consensus sequences design assays has been challenging due to sequence diversity led development specific RT-PCR each genogroup. Thus,...
Noroviruses are a leading cause of gastroenteritis worldwide. Although infections in healthy individuals self-resolving, immunocompromised at risk for chronic disease and severe complications. Chronic norovirus hosts often characterized by long-term virus shedding, but it is unclear whether this shed remains infectious. We investigated the prevalence, genetic heterogeneity, temporal aspects 1140 patients treated during 6-year period pediatric research hospital. Additionally, we identified 20...
Noroviruses are the leading cause of severe childhood diarrhea and foodborne disease worldwide. While they a major in all age groups, infections very young can be quite with annual estimates 50,000-200,000 fatalities children under 5 years old. In spite remarkable burden associated norovirus people, little is known about pathogenic mechanisms underlying diarrhea, principally because lack tractable small animal models. We recently demonstrated that wild-type neonatal mice susceptible to...
Viral contamination in oyster and mussel samples was evaluated after a massive storm with hurricane wind named "Xynthia tempest" destroyed number of sewage treatment plants an area harboring many shellfish farms. Although up to 90% were found be contaminated 2 days the disaster, detected viral concentrations low. A 1-month follow-up showed rapid decrease positive samples, even for norovirus.
Betanodaviruses are small ssRNA viruses responsible for viral encephalopathy and retinopathy, otherwise known as nervous necrosis, in marine fish worldwide. These can be either horizontally or vertically transmitted have been sporadically detected invertebrates, which seem to one of the possible sources. Twenty-eight new betanodavirus strains were retrieved three molluscs species collected from different European countries between 2008 2015. The phylogenetic analyses revealed that bivalve...
Bivalve molluscs from Adriatic sea were analyzed for V. parahaemolyticus, cholerae e vulnificus presence. The isolates on TCBS Agar and m-CPC selected the basis of a new biochemical screening, that showed good performance, because among 2344 strains primary culture only 237 (10%) presumptively assigned to species interest. PCR analyses was performed target genes toxR hlyA, ctxA, tcpI (V. cholerae), toxR, tl, tdh, trh parahaemolyticus), vvhA viuB vulnificus). Among 9 confirmed belong...