A5072929298- Nutritional Studies and Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Risk Factors
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Vitamin D Research Studies
- Birth, Development, and Health
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Health disparities and outcomes
- Genetic Associations and Epidemiology
- Sleep and related disorders
- Sodium Intake and Health
- Diet, Metabolism, and Disease
- Nutrition, Genetics, and Disease
- Heavy Metal Exposure and Toxicity
- Peripheral Artery Disease Management
- Diabetes and associated disorders
- Vitamin C and Antioxidants Research
- Diabetes Management and Research
- Heart Rate Variability and Autonomic Control
- Alcohol Consumption and Health Effects
- Cerebrovascular and Carotid Artery Diseases
- Gestational Diabetes Research and Management
Huazhong University of Science and Technology
2021-2025
Nanjing Maternity and Child Health Care Hospital
2024
Nanjing Medical University
2024
Fudan University
2023-2024
Nantong University
2024
Tulane University
2021-2022
National University Health System
2017-2021
National University of Singapore
2017-2021
Chinese Academy of Agricultural Sciences
2020
Institute of Food Science and Technology
2020
OBJECTIVE Although carotenoids have been suggested to exhibit antioxidant properties, some experimental studies reported that β-carotene may show pro-oxidant effects under certain conditions. Current evidence regarding the cardiovascular of among patients with type 2 diabetes (T2D) is scarce. This study aimed prospectively examine associations individual serum carotenoid concentrations mortality adults T2D. RESEARCH DESIGN AND METHODS analysis included 3,107 individuals T2D from Third...
Importance The associations of serum folate and vitamin B 12 levels with cardiovascular outcomes among patients type 2 diabetes (T2D) remain unclear. Objective To investigate the risk disease (CVD) mortality individuals T2D. Design, Setting, Participants This prospective cohort study included 8067 T2D who participated in National Health Nutrition Examination Survey (NHANES) from 1999 through 2014 NHANES III (1988-1994). American Diabetes Association criteria were used to define Data analyzed...
Background The influence of overall lifestyle behaviors on diabetic microvascular complications remains unknown. In addition, the potential mediating biomarkers underlying association is unclear. This study aimed to examine associations combined factors with risks total and individual among patients type 2 diabetes (T2D) explore mediation effects metabolic biomarkers. Methods findings retrospective cohort included 15,104 T2D free macro- at baseline (2006 2010) from UK Biobank. Healthy...
Importance Improved understanding of trends in the proportion individuals with metabolically healthy obesity (MHO) may facilitate stratification and management inform policy efforts. Objectives To characterize prevalence MHO among US adults obesity, overall by sociodemographic subgroups. Design, Setting, Participants This survey study included 20 430 adult participants from 10 National Health Nutrition Examination Survey (NHANES) cycles between 1999-2000 2017-2018. The NHANES is a series...
To test the causal effect of childhood BMI on adult cardiometabolic diseases using a Mendelian randomization analysis.We used 15 single nucleotide polymorphisms as instrumental variables for to summary-level data from consortia.We found that 1-SD increase in (kg/m2) was associated with an 83% risk type 2 diabetes (odds ratio [OR] 1.83 [95% CI 1.46, 2.30]; P = 2.5 × 10-7) and 28% coronary artery disease (CAD) (OR 1.28 1.17, 1.39]; 2.1 10-8) at Bonferroni-adjusted level significance (P <...
<h3>Importance</h3> The joint association of antihypertensive medication use and healthy lifestyle with mortality among individuals hypertension is unclear. <h3>Objective</h3> To examine the factors combined use, as well changes in lifestyle, all-cause cause-specific hypertension. <h3>Design, Setting, Participants</h3> This cohort study used data from Dongfeng-Tongji cohort, a long-term, prospective including employees at manufacturer China, baseline 2008 to 2010. Participants were followed...
OBJECTIVE Evidence is limited regarding the associations between vitamin D status and microvascular complications in individuals with type 2 diabetes (T2D), among whom deficiency or insufficiency particularly common. In this study we aimed to prospectively investigate of serum 25-hydroxyvitamin [25(OH)D] receptor (VDR) polymorphisms risk diabetic complications. RESEARCH DESIGN AND METHODS This analysis included 14,709 participants T2D who were free from UK Biobank. Incidence was ascertained...
Several epidemiological studies have suggested that vitamin D status is associated with risk of dementia in general populations. However, due to the synergistic effect between diabetic pathology and neuroinflammation, prothrombotic profile patients diabetes, whether among diabetes unclear. This study aimed investigate associations circulating levels risks all-cause dementia, Alzheimer disease (AD), vascular (VD) adults type 2 (T2D).This included 13,486 individuals (≥60 years) T2D free at...
Importance Adherence to a healthy lifestyle is associated with lower risks of adverse outcomes. However, trends in multiple factors and overall status among US adults recent years are unknown. Objective To examine adults. Design, Setting, Participants This serial cross-sectional study used nationally representative data from 10 National Health Nutrition Examination Survey (NHANES) cycles (nine 2-year 1999 2016 1 combined cycle 2017 March 2020) 20 or older. Data were analyzed December 10,...
Abstract Aims The relationship between uric acid (UA) concentrations and the risk of cardiovascular disease (CVD), especially for subtypes CVD among individuals with chronic kidney (CKD), is not well understood. This study aimed to investigate whether UA concentration was associated all-cause mortality CKD. Methods results A total 27 707 CKD, free at recruitment from Kailuan Study, were included. Cox proportional hazards regression models used compute hazard ratios (HRs) 95% confidence...
Abstract Parkinson disease (PD) has become one of the most rapidly growing causes disability among older population and social isolation is a major concern in PD community. However, relationship between future risk remains unclear. This study included 192,340 participants aged 60 or who were free dementia at baseline from UK Biobank study. Social was measured using composite score derived three questions on number household, frequency friend/family visits, leisure/social activities. Incident...
Importance Although the EAT-Lancet Commission has recently proposed a planetary health diet (PHD) to promote human and environmental health, little is known about how PHD affects environment mortality risk among an Asian population. Objective To investigate whether score associated with impacts outcomes in Chinese cohort living Singapore. Design, Setting, Participants This study used data from Singapore Health Study. Eligible participants were without cardiovascular disease cancer at...
Inadequate calcium intake is common in the US. Trends among US population have been less studied, especially more recent years. We used data from National Health and Nutrition Examination Survey (NHANES) 1999–2000 to 2017–2018 study trends derived diet dietary supplements aged 2 years, stratified by sex, age group, race, ethnicity. Among 80,880 participants included our study, a substantial portion consistently lacked sufficient intake, even when considering supplements. Concerning were...
Scope Among patients with diabetes, who have modified nutritional behavior and a higher risk of cardiovascular disease (CVD), the influence ultraprocessed foods (UPFs) on CVD remains unknown. The study aims to evaluate association between UPF intake among individuals type 2 diabetes (T2D) further examine potential biological pathways linking association. Methods results This includes 5405 participants T2D provided at least one 24‐h dietary recall from UK Biobank study. In fully adjusted...