- Lung Cancer Research Studies
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Anesthesia and Pain Management
- Management of metastatic bone disease
- Enhanced Recovery After Surgery
- Antimicrobial Resistance in Staphylococcus
- Anesthesia and Sedative Agents
- Neuroendocrine Tumor Research Advances
- Cerebrovascular and Carotid Artery Diseases
- Cancer Immunotherapy and Biomarkers
- Acute Ischemic Stroke Management
- Vector-borne infectious diseases
- Nausea and vomiting management
- Lung Cancer Treatments and Mutations
- Mycobacterium research and diagnosis
- Lung Cancer Diagnosis and Treatment
- Hemostasis and retained surgical items
- Bladder and Urothelial Cancer Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nanopore and Nanochannel Transport Studies
- Kidney Stones and Urolithiasis Treatments
- Groundwater flow and contamination studies
- Coronary Artery Anomalies
- Cholangiocarcinoma and Gallbladder Cancer Studies
Third Hospital of Hebei Medical University
2025
Hebei Medical University
2025
Sichuan University
2019-2025
West China Hospital of Sichuan University
2019-2025
Henan Cancer Hospital
2020-2024
Zhengzhou University
2022-2024
Shanghai Pulmonary Hospital
2023-2024
Tongji University
2023-2024
National Institute for Communicable Disease Control and Prevention
2024
Yuhuangding Hospital
2024
The resistance of commonly used clinical antibiotics, such as daptomycin (DAP), has become increasingly serious in the fight against Staphylococcus aureus (S. aureus) infection. It is essential to explore key pathogenicity-driven genes/proteins bacterial infection and antibiotics resistance, which contributes develop novel therapeutic strategies S. infections. nt5 gene aureus, encoding 5'-nucleotidase (NT5), nearly unknown for its function drug Herein, reveal role ability we performed...
Abstract Objective This study aims to systematically validate the reliability and applicability of Iliac Tilt (IT) as a parameter for sagittal balance assessment, explore its relationship with traditional parameters such Pelvic (PT) Pubic-Sacral Angle (PSA), analyze performance across different stages skeletal development. Methods A retrospective was conducted 118 healthy pediatric participants. Full-length radiographs were obtained using advanced EOS imaging system, relevant plane measured...
Aim: Hemorrhagic transformation is the major complication of intravenous thrombolysis. Calcification used widely as an imaging indicator atherosclerotic burden and cerebrovascular function. The relationship between intracranial calcification hemorrhagic has not been explored fully. We aimed to identify quantify in main cerebral vessels investigate correlations quantitative parameters, transformation, prognosis.
The prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) is rapidly increasing worldwide in recent decades and poses a challenge for today's clinical practice. Rapid detection CRKP can avoid inappropriate antimicrobial therapy save lives. Traditional methods are extremely time-consuming; PCR other sequencing too expensive technologically demanding, making it hard to meet the demands. Nanopore assay has been used screening biomarkers diseases recently because its high sensitivity,...
To evaluate the effect of dezocine combined with propofol on painless gastroscopy in patients suspect gastric carcinoma.Forty-three carcinoma who have underwent were retrospectively analyzed. For 43 patients, 21 received 1 mg/kg for (control group) and other 22 cases 20 µg/kg plus (experiment group). The vital indexes (heart rate [HR], respiratory [RR], mean arterial pressure [MAP], SpO2%), side effects, recovery time recorded at point T1 (before dosing), T2 (disappearance eyelash reflex),...
Abstract Introductions The spine is one of the most common sites metastasis for malignancies. This study aimed to compare predictive performance seven commonly used prognostic scoring systems surgically treated metastases. It expected assist surgeons in selecting appropriate support clinical decision‐making and better inform patients. Methods We performed a retrospective involving 268 patients with metastases between 2017 2020 at single regional oncology center China. revised Tokuhashi,...
The advantages of anterior surgery for severe ossification the posterior longitudinal ligament in cervical spine have been reported. However, it is more technically demanding and associated with a high risk surgery-related complications. purpose this study was to evaluate feasibility decompression techniques spine. Between June 2008 December 2011, twenty-two patients (16 men 6 women; average age, 58 years [range, 45–72 years]) who underwent corpectomy fusion were studied retrospectively....
Abstract Purpose The NCCN guidelines do not recommend surgery for T3–4N0M0/T1–4N1–2M0 small cell lung cancer (SCLC) due to a lack of evidence. Methods Data patients with SCLC were extracted from the Surveillance, Epidemiology, and End Results (SEER) database determine impact on this population. Kaplan–Meier method, univariable multivariable Cox proportional hazard regression, propensity score matching (PSM) used compare overall survival (OS) between non-surgery groups. In addition, we...
Background: To explore the impact of use vasoactive drugs in donation after cardiac death (DCD) donors on graft function, with an attempt to guide clinical practices organ preservation and DCD kidney transplantation.
Pasteurella multocida is a zoonotic pathogen causing serious diseases in humans and animals. Here, we report P. from wildlife on China's Qinghai-Tibet plateau with novel capsular serotype, forming single branch the core-genome phylogenetic tree: four strains isolated dead Himalayan marmot (Marmota himalayana) one genome assembled metagenomic sequencing of Woolly hare (Lepus oiostolus). Four were identified as subspecies was septica. The mouse model showed that challenge strain killed mice...
8044 Background: Chemoradiotherpay plus immunotherapy is recommended for unresectable locally-advanced non-small cell lung cancer (NSCLC) based on PACIFIC trial. However, it unclear whether surgery can provide survival benefit patients with tumors initially transformed into resectable ones after chemoimmunotherapy. This trial aims to investigate the efficacy and safety of therapeutic regimen chemoimmunotherapy or radiotherapy. Methods: Patients stage IIIB-IIIC NSCLC were enrolled receive 4...
Surveillance for animal plague was conducted in the
Patients with spinal metastases undergoing surgical treatment face challenges related to preoperative anemia, intraoperative blood loss, and frailty, emphasizing the significance of perioperative management. This retrospective analysis aimed assess correlation between hemoglobin-related parameters outcomes, identifying key markers aid in
A 56-year-old man with a 5-year history of paroxysmal palpitations, which have worsened over the past year, was diagnosed atrial fibrillation. During evaluation, transesophageal echocardiography revealed left atrium (LA) tumoral mass attached to septal fossa ovale, intra-tumoral blood flow and stream draining from mass. Both coronary computed tomography angiography demonstrated coro-cameral fistula connection between circumflex artery (LCX) branch LA. In addition, they showed feeding...
Introduction: The present study aimed to explore the potential effect of ulinastatin on renal function and long-term survival in patients receiving cardiac surgery with cardiopulmonary bypass (CPB). Methods: This prospective cohort was conducted at Fuwai Hospital, Beijing, China. Ulinastatin applied after induction anesthesia. primary outcome rate new-onset postoperative acute kidney injury (AKI). Moreover, a 10-year follow-up until January 2021. Results: AKI significantly lower group than...
We aimed to identify effective routinely collected laboratory biomarkers for predicting postoperative outcomes in surgically treated spinal metastases and attempted establish an prediction model.This study included 268 patients with at a single institution. evaluated patient determine trends predict survival. The markers white blood cell (WBC) count, platelet neutrophil lymphocyte hemoglobin, albumin, alkaline phosphatase, creatinine, total bilirubin, calcium, international normalized ratio...
Objectives: To our knowledge, no previous studies have investigated the impact of stroke severity on smoking paradox after intravenous thrombolysis (IVT). We aimed to explore contribution association between and prognosis IVT. Methods: enrolled consecutive patients who received IVT within 4.5 hours from onset. A logistic regression model was used estimate unadjusted adjusted odds ratios (ORs) with their 95% confidence intervals (CIs) for poor functional outcome mortality at 3 months....