A5100385831- Healthcare Systems and Reforms
- Alcoholism and Thiamine Deficiency
- Health Systems, Economic Evaluations, Quality of Life
- Enzyme Production and Characterization
- Pharmaceutical Economics and Policy
- Tissue Engineering and Regenerative Medicine
- Studies on Chitinases and Chitosanases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pharmaceutical Practices and Patient Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Biofuel production and bioconversion
- Biochemical Acid Research Studies
- Cytokine Signaling Pathways and Interactions
- Esophageal and GI Pathology
- Frequency Control in Power Systems
- Ferroptosis and cancer prognosis
- Psychological and Educational Research Studies
- Synthesis and Biological Activity
- Treatment of Major Depression
- Health disparities and outcomes
- S100 Proteins and Annexins
- Marine Sponges and Natural Products
- Digital Imaging for Blood Diseases
- Autism Spectrum Disorder Research
- Bipolar Disorder and Treatment
Zhejiang Chinese Medical University
2025
Fuzhou University
2024-2025
Huazhong University of Science and Technology
2018-2024
Tongji Hospital
2024
Wuhan Donghu University
2023-2024
Wuhan University
2023-2024
Southeast University
2023
University of International Business and Economics
2023
Shenyang Ligong University
2022
Tianjin Medical University General Hospital
2022
Three new dihydroisocoumarin penicimarins G–I (1–3), together with one known (4) and three meroterpenoids (5–7), were obtained from a fungus Penicillium citrinum isolated the mangrove Bruguiera sexangula var. rhynchopetala collected in South China Sea. Their structures elucidated by detailed analysis of spectroscopic data. The absolute configuration 1 was determined X-ray diffraction using Cu Kα radiation. configurations 2 3 comparison their circular dichroism (CD) spectra literature. All...
Abstract: The increasing prevalence of brain injuries resulting in cognitive and motor function impairments poses a substantial global medical challenge. Nerve repair therapies offer promise for addressing injury-related disorders. Ferroptosis, as cell death mechanism associated with oxidative stress inflammation. Certain ferroptosis inhibitors, such iron chelators antioxidants, exhibit therapeutic potential conditions. This review explores the fundamental processes mechanisms that regulate...
Scaffolds mimicking hierarchical features of native extracellular matrices may facilitate cell growth and anatomical tissue regeneration. In our previous study, esophageal basement membrane (BM) was shown to be composed interwoven fibers with mean diameter 66 ± 24 nm (range 28–165 nm) abundant pores unequal sizes. The main matrix (ECM) contents found in porcine BM were collagen IV, laminin, entactin, proteoglycans. this work, biodegradable polycaprolactone (PCL) silk fibroin (SF) spun...
Abstract Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in the treatment of hematological malignancies. Based on immunomodulatory capability CAR-T cells, efforts have turned toward exploring their potential treating autoimmune diseases. Bibliometric analysis 210 records from 128 academic journals published by 372 institutions 40 countries/regions indicates a growing number publications for diseases, covering range subtypes such as systemic lupus erythematosus,...
Objectives Optimizing the pharmaceutical industrial structure is key mission of China’s healthcare reform. From perspective, this study empirically evaluated impact national volume-based procurement (NVBP) policy on market concentration in hospital-end drug market. Methods This used data public medical institutions which obtained from database. A quasi-natural experiment was designed involving eleven pairs matched treatment-control region combinations, with NVBP as intervention measure. The...
Objectives In order to understand the influencing factors of medication-taking behaviour in patients with chronic diseases, reveal deep-seated causes underlying phenomenon polypharmacy, explore formation rules risk perception polypharmacy and how affect medication decision-making diseases. Design A qualitative descriptive design was used. Study data were collected through semi-structured interviews physicians. We used grounded theory approach refine factors, followed by interpretative...
<title>Abstract</title> <bold>Background: </bold>Exploring the relationship between polypharmacy behaviors and depressive symptoms in patients with chronic diseases is crucial for public health. The purpose of this study was to explore depression diseases. <bold>Methods:</bold><italic> </italic>A cluster sampling survey initially conducted March-April 2019 8 administrative districts Wuhan. Depressive were measured using Center Epidemiological Studies-Depression Scale (CES-D10). To reduce...
Purpose Given the increasing organizational need for having a thriving workforce due to fast-growing and competitive knowledge-based service economy growing demand explore new factors that may benefit individuals excel at work. Drawing upon intrinsic motivation perspective, with Chinese sample ( N = 309), authors aimed investigate whether work-related curiosity (WRC) create conditions indirectly promote employees' workplace via task focus this mediation was moderated by an individual's...
Lytic polysaccharide monooxygenases (LPMOs) have the potential to improve recalcitrant hydrolysis by oxidizing cleavage of glycosidic bond. Streptomyces species are major chitin decomposers in soil ecological environments and encode multiple lpmo genes. In this study, we demonstrated that transcription gene, Sclpmo10G, coelicolor A3(2) (ScA3(2)) strain is strongly induced chitin. The ScLPMO10G protein was further expressed Escherichia coli characterized vitro. showed oxidation activity...
Background With the accelerated ageing of population and growing prevalence various chronic diseases in China, self-medication plays an increasingly important role complementing health care system due to its convenience economy. Objective This study aimed investigate incidence amount expenditure among middle-aged older adults explore factors associated with them. Methods A total 10,841 respondents aged 45 years from China Health Retirement Longitudinal Study (CHARLS) wave 4 which conducted...
Abstract Background Adult child are used to taking the responsibility of care their older parents in Chinese culture. However, migration adult is not uncommon now context urbanization China. The purpose this study explore impact child’s on health status and utilization with chronic diseases left behind. Methods data 2015 nationally representative longitudinal survey aged population China were study. Binary logistic regression was evaluate Results About a quarter respondents (25.5%) had at...
Introduction: The increasing mortality in patients with sepsis-induced pulmonary fibrosis owes to a lack of effective treatment options. This study aims explore the possibility and possible targets Reduning prevention sepsis-related fibrosis. Methods: active components were searched screened from database analysis platform traditional Chinese medicine (TCM) system pharmacology. GeneCards, human genome database, DisGeNET OMIM checked determine associated DAVID Bioinformatics Resources 6.8 was...
Introduction: This study evaluated quantitatively the impact of first batch catalog Key Monitoring and Rational Use Drugs (KMRUD) in Hubei Province on policy-related drug use expenditures. Methods: is aimed to provide a basis for successful implementation subsequent catalogs KMRUD, which may promote standardization clinical application related drugs effectively reduce expenses patients. Data procurement records from January 2018 June 2021 were obtained Drug Centralized Procurement Platform...
We suggested using an Azure Kinect sensor to evaluate the dynamic balance ability of children with autism spectrum disorder (ASD). Two metrics, i.e., body mass center fluctuation (BMCF) and upper limb swing (ULS), were extracted from trajectories 32 joints' movement during beam test. Findings showed that ASD had lower BMCF ULS than typically developing (TD) children. Furthermore, prediction achieved a maximal accuracy 79% AUC value 0.69.
Abstract Carbon nanotubes (CNTs) have increasingly been used in a wide variety of applications. However, because their needle-shape morphology, biopersistence and mode exposure similar to those asbestos which is known carcinogen causing lung mesothelioma, there has great concern about potential carcinogenicity. In this study, we investigated the effect long-term CNT on proliferative invasive properties human pleural mesothelial cells. We found that chronic Met5A cells low-dose non-cytotoxic...