A5080431297- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Viral-associated cancers and disorders
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Homelessness and Social Issues
- Sex work and related issues
- Food Security and Health in Diverse Populations
- Hepatitis C virus research
- Adolescent Sexual and Reproductive Health
- Polyomavirus and related diseases
- Participatory Visual Research Methods
- Hepatitis B Virus Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Health Policy Implementation Science
- Medical Coding and Health Information
- Opioid Use Disorder Treatment
- Cytomegalovirus and herpesvirus research
- Syphilis Diagnosis and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Primary Care and Health Outcomes
- Community Health and Development
- Reproductive Health and Contraception
- Lymphoma Diagnosis and Treatment
AIDS Vancouver
2015-2025
University of British Columbia
2019-2025
Simon Fraser University
2016-2025
St. Paul's Hospital
2012-2024
St. Michael's Hospital
2022-2024
University of Toronto
2022-2024
Unity Health Toronto
2024
Public Health Ontario
2024
Ontario HIV Treatment Network
2022-2023
St Michaels Hospital
2023
Objective To establish the reliability and validity of a shortened (10-item) depression scale used among HIV-positive patients enrolled in Drug Treatment Program British Columbia, Canada. Methods The 10-item CES-D (Center for Epidemiologic Studies Depression Scale) was examined 563 participants who initiated antiretroviral therapy (ART) between August 1, 1996 June 30, 2002. Internal consistency measured by Cronbach’s alpha. Using original 20 as primary criteria, comparisons were made using...
Cancer remains an important cause of morbidity and mortality in people with human immunodeficiency virus (PWHIV) on effective antiretroviral therapy (ART). Estimates cancer-attributable can inform public health efforts.
Pregnancy incidence rates among women living with HIV (WLWH) have increased over time due to longer life expectancy, improved health status, and access prevention benefits of combination antiretroviral therapy (cART). However, it is unclear whether intended or unintended pregnancies are contributing observed increases.We analyzed retrospective data from the Canadian Women's Sexual Reproductive Health Cohort Study (CHIWOS). Kaplan-Meier methods GEE Poisson models were used measure cumulative...
The objective of this study is to evaluate the incidence non-AIDS defining malignancies (NADMs) among people living with HIV/AIDS (PLWHA) in British Columbia, focusing on clinical correlates, highly active antiretroviral therapy (HAART) use, and survival, order elucidate mechanisms for NADM development. A retrospective population based analysis was carried out individuals that began their treatment between 1996 2008. There were 145 (2.95%) NADMs 123 (2.50%) AIDS (ADMs) identified 4918 PLWHA...
SummaryBackgroundLife expectancy of people with HIV has increased considerably. We used data from the Comparative Outcomes And Service Utilization Trends (COAST) study to examine sex differences in life and mortality between 1996 2020 among British Columbia (BC), Canada.MethodsCOAST, a population-based cohort study, includes clinical administrative health on virtually all BC. calculated for at ages 20, 40, 55 years stratified by calendar period. Cox regression model associations all-cause...
Abstract Background Despite rolling out publicly-funded hepatitis C virus (HCV) treatment across the province of British Columbia (BC), Canada, 35% people returning positive HCV RNA results in 2020 did not initiate treatment. The epidemic Canada continues to disproportionately impact who use drugs and yet, this population has lowest proportional uptake Evidence suggests linkages healthcare after diagnosis is one key factors that impacts among priority population. Hep Connect pilot project...
Objective: We characterized sociodemographic and behavioural factors associated with mortality among people living HIV (PLWH) in British Columbia (BC), Canada. Design: used purposive sampling to recruit a representative cohort of PLWH aged ≥19 years from January 2016-September 2018. Participants completed survey consented link their data the BC Vital Statistics Agency, where deaths were recorded. Methods: conducted bivariate analyses compare characteristics between participants who died...
Abstract Background Hepatitis C virus (HCV) is a major health threat in Canada. In British Columbia (BC) province, 1.6% of the population had been exposed to HCV by 2012. Prevalence and incidence are very high populations people who use drugs (PWUD) sex workers (SW), may experience unique barriers healthcare. Consequently, they less likely be treated for HCV. Overcoming these critical elimination. This research sought explore healthcare experiences PWUD SW how impact their willingness engage...
Community-based participatory research (CBPR) has a long history within HIV research, yet little work focused on facilitating team-based data analysis CBPR. Our team adapted Thorne's interpretive description (ID) for CBPR analysis, using color-coded "sticky notes" system to conduct fragmentation and synthesis. Sticky notes were used record, visualize, communicate emerging insights over the course of 11 in-person sessions. Data strategies employed in an iterative four-step process that was...
Abstract Background Informed by recent studies demonstrating the central role of plasma HIV-1 RNA viral load (VL) on HIV transmission, interventions to employ antiretroviral treatment as prevention (TasP) are underway. To optimize these efforts, evidence is needed identify factors associated with both non-suppressed VL and risk behaviours. Thus, we sought assess possible played exposure correctional facilities non-suppression used syringe lending among HIV-seropositive people who use...
This study examined the prevalence and correlates associated with lifetime recent violence among a sample of harder-to-reach human immunodeficiency virus (HIV)-positive women living in British Columbia (BC), Canada. Interviewer-led surveys 1000 participants gathered quantitative data on social, economic, structural characteristics such as housing status, relationship family structure, history drug use, sexual behavior. Logistic regression analysis modeled associations between independent...
Purpose The Comparative Outcomes And Service Utilization Trends (COAST) Study in British Columbia (BC), Canada, was designed to evaluate the determinants of health outcomes and care services use among people living with HIV (PLHIV) as they age period following introduction combination antiretroviral therapy (cART). study also assesses how age-associated comorbidities PLHIV may differ from those observed general population. Participants COAST established through a data linkage between two...
The effectiveness of highly active antiretroviral therapy (HAART) in preventing disease progression can be negatively influenced by the high prevalence substance use among patients. Here, we quantify effect history injection drug and alcoholism on virologic immunologic response to HAART. Clinical survey data, collected at start HAART interview date, were based study Longitudinal Investigations into Supportive Ancillary Health Services (LISA) British Columbia, Canada. Substance was a...
The United States National HIV/AIDS Strategy established goals to reduce disparities in retention human immunodeficiency virus (HIV) care, antiretroviral therapy (ART) use, and viral suppression. impact of sex, age, sexual HIV acquisition risk (ie, heterosexual vs same-sex contact) on the magnitude HIV-related racial/ethnic is not well understood.We estimated age-stratified differences 5-year restricted mean percentage person-time spent ART, virally suppressed among 19 521 women (21.4%), men...
Cisgender women with HIV experience an elevated risk of cervical cancer compared HIV-negative women, but this can be prevented through regular screening. Our study objective was to measure adherence current national screening guidelines among in 3 Canadian provinces and identify factors associated delays.We conducted a cross-sectional using the baseline questionnaire Women's Sexual Reproductive Health Cohort Study (CHIWOS). Participants were recruited clinics, peers community organizations...
People living with HIV (PLWHA) adequate access to modern combination antiretroviral therapy (cART) are longer and experiencing reduced AIDS-related morbidity mortality. However, increases in non-AIDS related conditions, such as certain cancers, have accompanied these therapeutic advances over time. As such, our study objective was determine the impact of on all-cause lung cancer-specific mortality amongst PLWHA diagnoses non-small-cell cancer (NSCLC) HIV-negative individuals NSCLC. This...
Abstract Objective: Food insecurity, or self-reports of inadequate food access due to limited financial resources, remains prevalent among people living with HIV (PLHIV). We examined the impact insecurity on combination antiretroviral therapy (cART) adherence within an integrated care programme that provides services PLHIV, including two meals per day. Design: Adjusted OR (aOR) were estimated by generalized estimating equations, quantifying relationship between (exposure) and cART (outcome)...
Abstract Introduction The COVID‐19 pandemic has changed healthcare service delivery. We examined the overall impact of on people living with HIV in British Columbia (BC), Canada, a special focus potential antiretroviral treatment interruptions (TIs). Methods Purposive sampling was used to enrol aged ≥19 years across BC into STOP HIV/AIDS Program Evaluation study between January 2016 and September 2018. Participants completed surveys at baseline enrolment 18 36 months later. Additional...
People with HIV are at higher risk of infection-related cancers than the general population, which could be due, in part, to immune dysfunction. Our objective was examine associations between 4 CD4 count measures as indicators function and infection-unrelated cancer risk.