A5114547021- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Sepsis Diagnosis and Treatment
- Sodium Intake and Health
- Eosinophilic Esophagitis
- Hepatitis Viruses Studies and Epidemiology
- Genetic factors in colorectal cancer
- Gastroesophageal reflux and treatments
- Colorectal Cancer Treatments and Studies
- Selenium in Biological Systems
- Tea Polyphenols and Effects
- Cancer Risks and Factors
- Mycobacterium research and diagnosis
- Immune Cell Function and Interaction
- Curcumin's Biomedical Applications
- HIV, Drug Use, Sexual Risk
- Breast Lesions and Carcinomas
- Neurological Disease Mechanisms and Treatments
- Animal Virus Infections Studies
- Traditional Chinese Medicine Analysis
- Breast Cancer Treatment Studies
- Phytochemistry and Biological Activities
- Dialysis and Renal Disease Management
Henan Agricultural University
2023
Zhejiang Center for Disease Control and Prevention
2022
Huazhong Agricultural University
2022
Guangdong Provincial People's Hospital
2022
Beijing YouAn Hospital
2019-2021
Capital Medical University
2019-2021
University of Electronic Science and Technology of China
2021
Nanjing University
2020
Chinese PLA General Hospital
2019
Zhejiang University
2019
The incidence of colorectal cancer (CRC) is rapidly increasing, and early detection plays a crucial role in improving the prognosis survival rates patients. This study aimed to assess diagnostic ability combined SDC2-KCNQ5-IKZF1 methylation levels plasma for CRC detection. A total 92 patients were recruited from Department General Surgery at Second Hospital Hebei Medical University, including 56 patients, 22 polyp adenoma 14 healthy controls. Plasma cfDNA was extracted test SDC2, KCNQ5,...
Triple-negative breast cancer (TNBC) is an aggressive malignancy with a poor prognosis. Data from the Surveillance, Epidemiology and End Results database (2010-2012) were used to identify 10,771 patients TNBC, we assessed effects of lymph node (LN) status on cancer-specific survival (BCSS) overall (OS). In our study, Kaplan-Meier plot showed that LN-negative (N0) had better outcomes than LN-positive ≥10 positive LNs (N3) exhibited worst regardless tumor size. A pairwise comparison no...
Recurrence is common for patients with chronic hepatitis B (CHB) who achieved virus (HBV) surface antigen (HBsAg) clearance after antiviral treatment. The aim of the study to explore possibility quantitative core antibody (Anti-HBc) level as a biomarker predict recurrence. A total 73 HBsAg were enrolled in this study, 16 cases recurrence and 57 non-recurrence. newly developed double-sandwich Anti-HBc immunoassay was used detect before therapy (baseline) at end therapy. Logistic regression...
Complement dependent cytotoxicity (CDC) significantly contributes to Rituximab (RTX) and Ofatumumab (OFA) efficacies in the treatment of B-cell non-Hodgkin's lymphoma (NHL) chronic lymphocytic leukemia (CLL).Human CD59 (hCD59) is a key complement regulatory protein that restricts formation membrane attack complex thereby inhibits CDC.hCD59 an important determinant sensitivity NHL CLL RTX OFA treatment.Recently, we developed specific potent hCD59 inhibitor, His-tagged ILYd4, which consists 30...
To explore the risk factors influencing short-term mortality of patients with sepsis in intensive care unit (ICU) and combined value predicting prognosis.A retrospective analysis was performed on 104 admitted to emergency ICU Jiangsu Provincial Hospital Traditional Chinese Medicine from January 2018 August 2019. Multiple general information containing gender, age, past history as well complications sequential organ failure assessment (SOFA) score, mean arterial pressure (MAP), blood routine...
To investigate postpartum hepatic flares and associated factors in highly viremic pregnant patients the immune tolerance phase who adopted telbivudine (LdT) treatment last trimester to reduce vertical transmission of hepatitis B virus.Hepatitis e antigen (HBeAg)-positive, women were recruited for this prospective study. Treatment with LdT was started from 28 weeks gestation. Virological biochemical markers examined before treatment, antepartum postpartum. Serial blood samples at same time...
Increasing evidence shows that selenium and polyphenols are two types of the most reported compounds in tumor chemoprevention due to their remarkable antitumor activity high safety profile. The cross-talk between is a hot research topic, combination valuable strategy for fighting cancer. current work investigated anti-peritoneal carcinomatosis (PC) effect nanoparticles (SeNPs) green tea (Camellia sinensis) polyphenol (-)-epigallocatechin-3-gallate (EGCG) mice bearing murine hepatocarcinoma...
妊娠期筛查HBV感染(简称筛查)可确定有无围产期母婴传播风险的妇女。制订本共识的目的是更新2009年美国预防医学工作组(USPSTF)关于孕妇HBV感染筛查的建议。USPSTF需要重新确认证据更新,以确定是否存在足够的新证据以改变先前建议。USPSTF通过文献复习以及临床病例管理对筛查的有效性和危害性进行了证据审查。最终USPSTF重申其先前的结论:有力证据表明,孕妇筛查HBV感染可带来实质性的益处。USPSTF建议为无明显相关症状或体征的育龄期妇女提供特定的临床预防服务。该建议是基于此服务的利弊端证据以
To determine whether deletion of TRPV1 exaggerates salt‐sensitive hypertension‐induced renal injury via activation chemokine receptor 2 (CCR2), wild type (WT) and TRPV1‐null mutant (TRPV1‐/‐) mice were subjected to uninephrectomy DOCA‐salt treatment for 4 weeks with or without selective CCR2 antagonist, RS504393. increased systolic blood pressure (SBP), urinary excretion albumin 8‐isoprostane, decreased creatinine clearance compared the control. also caused obvious glomerulosclerosis,...
Objective To investigate the clinical pattern,therapeutic principle and influencing factors of interstitial pneumonia in renal allograft recipients.Method The general information,clinical manifestation,treatment outcomes 30 recipients with after transplantation from Nov.2006 to Dec.2013 were analyzed retrospectively.Result Twenty-nine patients developed between 2 6 months post-transplant.The total course lasted for 34.9 ± 7.5 days on average.Chest CT scans used monitor severity each week.The...
Objective To investigate the safety and efficacy of pegylated interferon (PEG-IFN) ribavirin for chronic hepatitis C following renal transplantation.Method Nine adult transplant recipients ＞ 12-month duration,infected with virus (HCV),and stable graft function were recruited.All patients administered PEG-IFN-α 2b 50 μg/week,plus ribovirin 400-600 mg/day.HCV viral load was reexamined monthly.Consolidation therapy lasted 3-9 months after initial remission HCV-RNA.Viral response,adverse effects...